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Publikováno v:
Journal of the American Academy of Dermatology. 78(6)
Autor:
Alyx C. Rosen, Emily C. Case, Felipe Bochnia Cerci, Mario E. Lacouture, Shenhong Wu, Marigdalia K. Ramirez-Fort
Publikováno v:
American Journal of Clinical Oncology. 37:266-271
Everolimus is a mammalian target of rapamycin (mTOR) inhibitor approved for treatment of renal cell carcinoma, subependymal giant cell astrocytoma, breast cancer, and progressive neuroendocrine tumors of pancreatic origin. Its use may be hindered bec
Publikováno v:
Dermatologic Therapy. 26:135-148
In the past decade, the expanded use of targeted anticancer drugs has significantly prolonged survival in patients treated for a variety of cancers. Despite their increased specificity, agents such as epidermal growth factor receptor inhibitors (EGFR
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 97:1125-1133
Vandetanib is an oral inhibitor of vascular endothelial growth factor receptor, epidermal growth factor receptor, and rearranged during transfection tyrosine kinases. It is approved for the treatment of unresectable or metastatic medullary thyroid ca
Autor:
Diane Reidy-Lagunes, Patricia L. Myskowski, Mario E. Lacouture, Jason A. Konner, Melissa Pulitzer, Yevgeniy Balagula, Darren R. Feldman, Klaus J. Busam, Robert J. Motzer, Alyx C. Rosen, Belinda H. Tan
Publikováno v:
Cancer. 118:5078-5083
BACKGROUND: Dermatologic adverse events stemming from anticancer therapies have become an increasingly frequent clinical problem. Inhibitors of mammalian target of rapamycin (mTOR), such as temsirolimus and everolimus, have been associated with a hig
Autor:
Evangelos V. Badiavas, Robert S. Kirsner, Wellington Guzman, Wasif N. Khan, Tim Ioannides, Anna J. Nichols, Emily S. Clark, Alyx C. Rosen, Adrianna Gonzalez, Harold S. Rabinovitz
Publikováno v:
JAMA Dermatology. 154:927
Importance Squamous cell carcinoma (SCC) is the second most common form of skin cancer, and its incidence is increasing. When surgical management is not an option, finding a safe and efficacious treatment is a challenge. Mounting evidence suggests th
Autor:
Viswanath Reddy, Belum, Alyx C, Rosen, Natalia, Jaimes, George, Dranitsaris, Melissa P, Pulitzer, Klaus J, Busam, Ashfaq A, Marghoob, Richard D, Carvajal, Paul B, Chapman, Mario E, Lacouture
Publikováno v:
Cancer. 121(1)
The use of BRAF inhibitors may lead to the development of cutaneous toxicities such as rashes, photosensitivity, alopecia, palmoplantar erythrodysesthesia, and proliferative skin lesions, including keratoacanthomas (KAs) and cutaneous squamous cell c
Publikováno v:
Dermatologic Principles and Practice in Oncology: Conditions of the Skin, Hair, and Nails in Cancer Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44cc26b2b3bde9bf545bd38e57390e99
https://doi.org/10.1002/9781118590638.ch33
https://doi.org/10.1002/9781118590638.ch33
Autor:
Jennifer Sorrell, Yevgeniy Balagula, Dennis W. Raisch, Nicole E. Larsen, Beatrice Nardone, Milan J. Anadkat, Alyx C. Rosen, Dennis P. West, Vishvas Garg, Mario E. Lacouture
Publikováno v:
Anti-cancer drugs. 25(2)
The incidences of life-threatening toxicities such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are inconsistently reported. The potential association of anticancer agents with SJS or TEN has not been systematically investig