Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Alyssa R Merkel"'
Autor:
David B Vaught, Alyssa R Merkel, Conor C Lynch, James Edwards, Mohammed Noor Tantawy, Timothy Hilliard, Shan Wang, Todd Peterson, Rachelle W Johnson, Julie A Sterling, Dana Brantley‐Sieders
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
ABSTRACT EphA2 receptor tyrosine kinase (RTK) is highly expressed in breast tumor cells across multiple molecular subtypes and correlates with poor patient prognosis. In this study, the potential role of EphA2 in this clinically relevant phenomenon i
Externí odkaz:
https://doaj.org/article/e50828c08fb84f00868df19ee24dc038
Autor:
Nazanin S Ruppender, Alyssa R Merkel, T John Martin, Gregory R Mundy, Julie A Sterling, Scott A Guelcher
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15451 (2010)
Nearly 70% of breast cancer patients with advanced disease will develop bone metastases. Once established in bone, tumor cells produce factors that cause changes in normal bone remodeling, such as parathyroid hormone-related protein (PTHrP). While en
Externí odkaz:
https://doaj.org/article/12d271a4478f4658aec14a037015e14e
Autor:
David C. Florian, Natalie E. Bennett, Mateusz Odziomek, Jessalyn J. Baljon, Mohamed Wehbe, Alyssa R. Merkel, Melissa A. Fischer, Michael R. Savona, Julie A. Rhoades, Scott A. Guelcher, John T. Wilson
Publikováno v:
Cancer Research Communications. 3:223-234
When breast cancer metastasizes to bone, treatment options are limited. Failure to treat bone metastases is thought to be due to therapy-resistant features of the bone marrow microenvironment. Using a murine model of bone metastatic mammary carcinoma
Autor:
John T. Wilson, Scott A. Guelcher, Julie A. Rhoades, Michael R. Savona, Melissa A. Fischer, Alyssa R. Merkel, Mohamed Wehbe, Jessalyn J. Baljon, Mateusz Odziomek, Natalie E. Bennett, David C. Florian
Supplementary Figure 6: Concentration of CD11B+ cells in healthy STING NP-treated BM over time.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0903ee5eaabb5f50c94e47a316e5bac6
https://doi.org/10.1158/2767-9764.22546368
https://doi.org/10.1158/2767-9764.22546368
Autor:
John T. Wilson, Scott A. Guelcher, Julie A. Rhoades, Michael R. Savona, Melissa A. Fischer, Alyssa R. Merkel, Mohamed Wehbe, Jessalyn J. Baljon, Mateusz Odziomek, Natalie E. Bennett, David C. Florian
When breast cancer metastasizes to bone, treatment options are limited. Failure to treat bone metastases is thought to be due to therapy-resistant features of the bone marrow microenvironment. Using a murine model of bone metastatic mammary carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629d67c1b0a0ef59a15cd822683fc8fa
https://doi.org/10.1158/2767-9764.c.6551166.v1
https://doi.org/10.1158/2767-9764.c.6551166.v1
Autor:
Julie A. Sterling, Gregory R. Mundy, Lynn M. Matrisian, Babatunde O. Oyajobi, Alyssa R. Merkel, Barry G. Grubbs, Susan S. Padalecki, Mai P. Nguyen, Rachelle W. Johnson
Supplementary Figure 1 from TGF-β Promotion of Gli2-Induced Expression of Parathyroid Hormone-Related Protein, an Important Osteolytic Factor in Bone Metastasis, Is Independent of Canonical Hedgehog Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2aed51d09435bdf2338c70602d63f6
https://doi.org/10.1158/0008-5472.22391259.v1
https://doi.org/10.1158/0008-5472.22391259.v1
Autor:
Julie A. Sterling, Gregory R. Mundy, Lynn M. Matrisian, Babatunde O. Oyajobi, Alyssa R. Merkel, Barry G. Grubbs, Susan S. Padalecki, Mai P. Nguyen, Rachelle W. Johnson
Supplementary Figure Legends 1-2 from TGF-β Promotion of Gli2-Induced Expression of Parathyroid Hormone-Related Protein, an Important Osteolytic Factor in Bone Metastasis, Is Independent of Canonical Hedgehog Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3096a58fb4330f4481bab120c2453114
https://doi.org/10.1158/0008-5472.22391256.v1
https://doi.org/10.1158/0008-5472.22391256.v1
Autor:
Julie A. Sterling, Gregory R. Mundy, Lynn M. Matrisian, Babatunde O. Oyajobi, Alyssa R. Merkel, Barry G. Grubbs, Susan S. Padalecki, Mai P. Nguyen, Rachelle W. Johnson
Breast cancer frequently metastasizes to bone, in which tumor cells receive signals from the bone marrow microenvironment. One relevant factor is TGF-β, which upregulates expression of the Hedgehog (Hh) signaling molecule, Gli2, which in turn increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6db509590ea2e6a8d50c7e66f3d56f59
https://doi.org/10.1158/0008-5472.c.6503202.v1
https://doi.org/10.1158/0008-5472.c.6503202.v1
Autor:
Richard d'Arcy, Julie A. Rhoades, Jordan L. Hill, Scott A. Guelcher, Craig L. Duvall, Joseph P. Vanderburgh, Alyssa R. Merkel, Kathleen Moyer, Kristin A. Kwakwa, Sean K. Bedingfield, Sean K. Wang, Mukesh K. Gupta
Publikováno v:
ACS Nano
Breast cancer patients are at high risk for bone metastasis. Metastatic bone disease is a major clinical problem that leads to a reduction in mobility, increased risk of pathologic fracture, severe bone pain, and other skeletal-related events. The tr
Autor:
Julie A. Sterling, Milene N O Moritz, Alyssa R. Merkel, Heloisa S. Selistre-de-Araujo, Ean G. Feldman
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6906, p 6906 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6906, p 6906 (2021)
Integrins participate in the pathogenesis and progression of tumors at many stages during the metastatic cascade. However, current evidence for the role of integrins in breast cancer progression is contradictory and seems to be dependent on tumor sta