Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alyssa N. Russ"'
Autor:
Qiuchen Zhao, Megi Maci, Morgan R. Miller, Heng Zhou, Fang Zhang, Moustafa Algamal, Yee Fun Lee, Steven S. Hou, Stephen J. Perle, Hoang Le, Alyssa N. Russ, Eng H. Lo, Dmitry Gerashchenko, Stephen N. Gomperts, Brian J. Bacskai, Ksenia V. Kastanenka
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Background Alzheimer’s disease (AD) patients exhibit memory disruptions and profound sleep disturbances, including disruption of deep non-rapid eye movement (NREM) sleep. Slow-wave activity (SWA) is a major restorative feature of NREM slee
Externí odkaz:
https://doaj.org/article/1e5e4e5bc1d94426a2b8318ad4669b2b
Autor:
Yee Fun Lee, Alyssa N. Russ, Qiuchen Zhao, Stephen J. Perle, Megi Maci, Morgan R. Miller, Steven S. Hou, Moustafa Algamal, Zhuoyang Zhao, Hanyan Li, Noah Gelwan, Zhe Liu, Stephen N. Gomperts, Alfonso Araque, Elena Galea, Brian J. Bacskai, Ksenia V. Kastanenka
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Patients with Alzheimer’s disease (AD) exhibit non-rapid eye movement (NREM) sleep disturbances in addition to memory deficits. Disruption of NREM slow waves occurs early in the disease progression and is recapitulated in transgenic mouse
Externí odkaz:
https://doaj.org/article/ab1d3dd5af70461fa37743a95753e2eb
Autor:
Moustafa Algamal, Alyssa N. Russ, Morgan R. Miller, Steven S. Hou, Megi Maci, Leon P. Munting, Qiuchen Zhao, Dmitry Gerashchenko, Brian J. Bacskai, Ksenia V. Kastanenka
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Interneuron-specific lines reveal that somatostatin interneurons are hyperactive whereas pyramidal neurons and PV interneurons are ‘hypoactive’ in the APP/PS1 mouse model of Alzheimer’s Disease.
Externí odkaz:
https://doaj.org/article/9442891c7a3244869aae495ba0e754c4
Autor:
Maria Calvo-Rodriguez, Steven S. Hou, Austin C. Snyder, Elizabeth K. Kharitonova, Alyssa N. Russ, Sudeshna Das, Zhanyun Fan, Alona Muzikansky, Monica Garcia-Alloza, Alberto Serrano-Pozo, Eloise Hudry, Brian J. Bacskai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Calvo-Rodriguez et al. show elevated calcium levels in neuronal mitochondria in a mouse model of cerebral β-amyloidosis after plaque deposition, which precede rare neuron death events in this model. The mechanism involves toxic extracellular Aβ oli
Externí odkaz:
https://doaj.org/article/638a348449c44bb59f38a1bc9201bb6b
Autor:
Moustafa Algamal, Alyssa N. Russ, Morgan R. Miller, Steven S. Hou, Megi Maci, Leon P. Munting, Qiuchen Zhao, Dmitry Gerashchenko, Brian J. Bacskai, Ksenia V. Kastanenka
Alzheimer’s disease (AD) is characterized by synaptic loss and neuronal network dysfunction. These network deficits are mediated by early alterations in neuronal firing rates that coincide with amyloid plaque accumulation. Mounting evidence support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35b681277b73f949d1adcccc58f21714
https://doi.org/10.1101/2022.04.27.489759
https://doi.org/10.1101/2022.04.27.489759
Autor:
Yee Fun Lee, Brian J. Bacskai, Alyssa N. Russ, Sang-Zin Choi, Ksenia V. Kastanenka, Lavender Lariviere
Publikováno v:
eNeuro
Alzheimer’s disease (AD) is an incurable neurodegenerative disorder and a major cause of dementia. Some of the hallmarks of AD include presence of amyloid plaques in brain parenchyma, calcium dysregulation within individual neurons, and neuroinflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4d3b4ea73bb394b99d543586b190d2
https://pubmed.ncbi.nlm.nih.gov/33926907
https://pubmed.ncbi.nlm.nih.gov/33926907
Autor:
Elizabeth K. Kharitonova, Alyssa N. Russ, Eloise Hudry, Alona Muzikansky, Austin Snyder, Sudeshna Das, Maria Calvo-Rodriguez, Monica Garcia-Alloza, Brian J. Bacskai, Zhanyun Fan, Alberto Serrano-Pozo, Steven S. Hou
Publikováno v:
Nature Communications (2020) 11:2146
RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz
instname
RODIN: Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz
Universidad de Cádiz
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz
instname
RODIN: Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz
Universidad de Cádiz
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Mitochondria contribute to shape intraneuronal Ca2+ signals. Excessive Ca2+ taken up by mitochondria could lead to cell death. Amyloid beta (A beta) causes cytosolic Ca2+ overload, but the effects of A beta on mitochondrial Ca2+ levels in Alzheimer's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26b55b79ff36c7a4f5e2e60b93236be
http://hdl.handle.net/10498/23328
http://hdl.handle.net/10498/23328
Autor:
Maria, Calvo-Rodriguez, Steven S, Hou, Austin C, Snyder, Elizabeth K, Kharitonova, Alyssa N, Russ, Sudeshna, Das, Zhanyun, Fan, Alona, Muzikansky, Monica, Garcia-Alloza, Alberto, Serrano-Pozo, Eloise, Hudry, Brian J, Bacskai
Publikováno v:
Cell Stress
Alzheimer's disease (AD), the most common cause of dementia, affects millions of people worldwide. Suggested mechanisms of neurotoxicity in AD include impaired calcium (Ca2+) homeostasis and mitochondrial dysfunction, both contributing to neuronal da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::934e81241483e0dea069cbf1e79c3161
https://pubmed.ncbi.nlm.nih.gov/32656500
https://pubmed.ncbi.nlm.nih.gov/32656500