The influence of deoxygenation on Caribbean coral larval settlement and early survival

Autor: Jennifer E. Mallon, Alyssa M. Demko, Jennifer M. Sneed, Lilyana Newman, Carle Dugan, Andrew H. Altieri, Valerie Jean Paul, Maggie D. Johnson

Publikováno v: Frontiers in Marine Science, Vol 10 (2023)

Deoxygenation is emerging as a major threat to coral reefs where it can have catastrophic effects, including mass coral mortality. Some coral species cannot survive more than a few days of exposure to low oxygen conditions, while others can tolerate

Externí odkaz: https://doaj.org/article/ab45b728257e465e81710dd9e35b7d17

Biogeographic patterns of biosynthetic potential and specialized metabolites in marine sediments

Autor: Alexander B. Chase, Alexander Bogdanov, Alyssa M. Demko, Paul R. Jensen

Publikováno v: The ISME Journal.

While the field of microbial biogeography has largely focused on the contributions of abiotic factors to community patterns, the potential influence of biotic interactions in structuring microbial communities, such as those mediated by the production

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd29caa0b461263b693b793824a984b6
https://doi.org/10.1038/s41396-023-01410-3

The Natural Product Domain Seeker version 2 (NaPDoS2) webtool relates ketosynthase phylogeny to biosynthetic function

Autor: Leesa J. Klau, Sheila Podell, Kaitlin E. Creamer, Alyssa M. Demko, Hans W. Singh, Eric E. Allen, Bradley S. Moore, Nadine Ziemert, Anne Catrin Letzel, Paul R. Jensen

Publikováno v: Journal of Biological Chemistry
The Journal of biological chemistry, vol 298, iss 10

The Natural Product Domain Seeker (NaPDoS) webtool detects and classifies ketosynthase (KS) and condensation domains from genomic, metagenomic, and amplicon sequence data. Unlike other tools, a phylogeny-based classification scheme is used to make br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866d4dfc73fdc66467e6b35c9667eb3f
https://doi.org/10.1016/j.jbc.2022.102480

A community resource for paired genomic and metabolomic data mining

Autor: Lars Ridder, Tim S. Bugni, Jamshid Amiri Moghaddam, Florian Huber, Elke Dittmann, Kelly C. Weldon, Louis-Félix Nothias, Douglas Sweeney, Mingxun Wang, Paul R. Jensen, Letícia V. Costa-Lotufo, Christine Beemelmanns, Katherine R. Duncan, Nadine Ziemert, Xuanji Li, Dulce G. Guillén Matus, Chao Du, Neha Garg, Jae Seoun Hur, Elizabeth I. Parkinson, Raphael Reher, Nicholas J. Tobias, Alex A. Blacutt, Emily C Pierce, Michelle Schorn, J. Michael Beman, Simon Rogers, María Victoria Berlanga-Clavero, Martin Baunach, Fan Zhang, Deepa D. Acharya, Harald Gross, Hamada Saad, M. Caroline Roper, Anna Edlund, Jason M. Crawford, Daniel Petras, Alexandra Calteau, Benjamin-Florian Hempel, Seoung Rak Lee, Max Crüsemann, Neil L. Kelleher, Hosein Mohimani, David P. Fewer, Shaurya Chanana, Carmen Saenz, Lena Gerwick, Ki-Hyun Kim, Roderich D. Süssmuth, Jörn Piel, Diego Romero, Marnix H. Medema, Anelize Bauermeister, Christopher Drozd, Regan J. Thomson, Anne Boullie, Michael W. Mullowney, Karine Pires, Andrew C. McAvoy, Alexander A. Aksenov, Saefuddin Aziz, Raquel Castelo-Branco, Julia M. Gauglitz, Mitchell N. Muskat, Bart Cuypers, Emily C. Gentry, Yi Yuan Lee, Eric J. N. Helfrich, Tam Dang, Pieter C. Dorrestein, Liu Cao, Rachel J. Dutton, Gilles P. van Wezel, Helge B. Bode, Margherita Sosio, Asker Daniel Brejnrod, Gajender Aleti, Leonard Kaysser, Amaro E. Trindade-Silva, Willam W. Metcalf, Irina Koester, Tiago Leao, Katherine D. Bauman, Jessica C. Little, Evgenia Glukhov, Ellis C. O’Neill, Justin J. J. van der Hooft, Alyssa M. Demko, Alexander B. Chase, Marc G. Chevrette, Bradley S. Moore, Christian Martin H, Kapil Tahlan, Cameron R. Currie, Allegra T. Aron, Muriel Gugger, Kyo Bin Kang, Víctor J. Carrión, Michael J. Rust, Gabriele M. König, Carlos Molina-Santiago, Søren J. Sørensen, Marianna Iorio, Jean-Claude Dujardin, Daniel Männle, Chung Sub Kim, Laura M. Sanchez, Katherine N. Maloney, Stefan Verhoeven, Tristan de Rond

Publikováno v: Nature Chemical Biology
Nature Chemical Biology, Nature Publishing Group, 2021, ⟨10.1038/s41589-020-00724-z⟩
Nature Chemical Biology 17 (2021) 4
Nature Chemical Biology, 17(4), 363-368
Nature Chemical Biology, 17(4), 363-368. Nature Publishing Group
Nat Chem Biol
Schorn, M A, Verhoeven, S, Ridder, L, Huber, F, Acharya, D D, Aksenov, A A, Aleti, G, Moghaddam, J A, Aron, A T, Aziz, S, Bauermeister, A, Bauman, K D, Baunach, M, Beemelmanns, C, Beman, J M, Berlanga-Clavero, M V, Blacutt, A A, Bode, H B, Boullie, A, Brejnrod, A, Bugni, T S, Calteau, A, Cao, L, Carrión, V J, Castelo-Branco, R, Chanana, S, Chase, A B, Chevrette, M G, Costa-Lotufo, L V, Crawford, J M, Currie, C R, Cuypers, B, Dang, T, de Rond, T, Demko, A M, Dittmann, E, Du, C, Drozd, C, Dujardin, J-C, Dutton, R J, Edlund, A, Fewer, D P, Garg, N, Gauglitz, J M, Gentry, E C, Gerwick, L, Glukhov, E, Gross, H, Gugger, M, Matus, D G G, Helfrich, E J N, Hempel, B-F, Hur, J-S, Iorio, M, Jensen, P R, Kang, K B, Kaysser, L, Kelleher, N L, Kim, C S, Kim, K H, Koester, I, König, G M, Leao, T, Lee, S R, Lee, Y-Y, Li, X, Little, J C, Maloney, K N, Männle, D, Martin H., C, McAvoy, A C, Metcalf, W W, Mohimani, H, Molina-Santiago, C, Moore, B S, Mullowney, M W, Muskat, M, Nothias, L-F, O'Neill, E C, Parkinson, E I, Petras, D, Piel, J, Pierce, E C, Pires, K, Reher, R, Romero, D, Roper, M C, Rust, M, Saad, H, Saenz, C, Sanchez, L M, Sørensen, S J, Sosio, M, Süssmuth, R D, Sweeney, D, Tahlan, K, Thomson, R J, Tobias, N J, Trindade-Silva, A E, van Wezel, G P, Wang, M, Weldon, K C, Zhang, F, Ziemert, N, Duncan, K R, Crüsemann, M, Rogers, S, Dorrestein, P C, Medema, M H & van der Hooft, J J J 2021, ' A community resource for paired genomic and metabolomic data mining ', Nature Chemical Biology, vol. 17, no. 4, pp. 363-368 . https://doi.org/10.1038/s41589-020-00724-z
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Chemical Biology, 2021, ⟨10.1038/s41589-020-00724-z⟩
Nature chemical biology

International audience; Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to systematically document links between metabolome and (meta)genome data, aiding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bab3cd944ad174c6905009e2841f0d
https://hal-pasteur.archives-ouvertes.fr/pasteur-03153704/document

Detection of Natural Products and Their Producers in Ocean Sediments

Autor: Paul R. Jensen, Robert N. Tuttle, Pieter C. Dorrestein, Nastassia V. Patin, Clifford A. Kapono, Alyssa M. Demko, Mohamed S. Donia

Publikováno v: Applied and environmental microbiology. 85(8)

Thousands of natural products have been identified from cultured microorganisms, yet evidence of their production in the environment has proven elusive. Technological advances in mass spectrometry, combined with public databases, now make it possible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916b25f7b83d1641ad8ab2fdfc9aab3d
https://pubmed.ncbi.nlm.nih.gov/30737349