Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alyssa M. Blaise"'
Autor:
Alessandra Dall’Agnese, Jesse M. Platt, Ming M. Zheng, Max Friesen, Giuseppe Dall’Agnese, Alyssa M. Blaise, Jessica B. Spinelli, Jonathan E. Henninger, Erin N. Tevonian, Nancy M. Hannett, Charalampos Lazaris, Hannah K. Drescher, Lea M. Bartsch, Henry R. Kilgore, Rudolf Jaenisch, Linda G. Griffith, Ibrahim I. Cisse, Jacob F. Jeppesen, Tong I. Lee, Richard A. Young
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
The authors find that the insulin receptor forms dynamic clusters during insulin signaling and that these clusters become dysfunctional in insulin resistance. This dysfunction is partially rescued by metformin, a drug used to treat type 2 diabetes.
Externí odkaz:
https://doaj.org/article/b6a27a393d354ad08dc4d2e2cdc0f034
Autor:
Alyssa M Blaise, Ellen E Corcoran, Eve S Wattenberg, Yan-Ling Zhang, Jeffrey R Cottrell, Anthony J Koleske
Publikováno v:
Biology Methods & Protocols
Guanine nucleotide exchange factors (GEFs) are enzymes that promote the activation of GTPases through GTP loading. Whole exome sequencing has identified rare variants in GEFs that are associated with disease, demonstrating that GEFs play critical rol
Autor:
Joaquin Camara-Quintana, Julio D Montejo, Jeannine M Rockefeller, Daniel Duran, Sierra B Conine, Michael L. DiLuna, Alyssa M Blaise, Kristopher T. Kahle
Publikováno v:
Journal of neurosurgery. Pediatrics. 21(5)
OBJECTIVELumbar disc herniation (LDH) in the pediatric population is rare and exhibits unique characteristics compared with adult LDH. There are limited data regarding the safety and efficacy of minimally invasive surgery (MIS) using tubular retracto