Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alyssa Lesko"'
Autor:
Ann Sutherland, Alyssa Lesko
Publikováno v:
F1000Research, Vol 9 (2020)
Cell and tissue shape changes are the fundamental elements of morphogenesis that drive normal development of embryos into fully functional organisms. This requires a variety of cellular processes including establishment and maintenance of polarity, t
Externí odkaz:
https://doaj.org/article/fa2d0fb1087746abbd9b72a0713f4e69
Autor:
Jenifer R. Prosperi, Alyssa Lesko
Publikováno v:
Experimental Cell Research. 350:190-198
Adenomatous Polyposis Coli (APC) plays a critical role in cell motility, maintenance of apical-basal polarity, and epithelial morphogenesis. We previously demonstrated that APC loss in Madin Darby Canine Kidney (MDCK) cells increases cyst size and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997f4ad7600f47f7cec0c4c42ba1a8c8
https://doi.org/10.1016/j.yexcr.2016.11.021
https://doi.org/10.1016/j.yexcr.2016.11.021
Autor:
Adam Schwertner, Frank F. Yang, Jenifer R. Prosperi, Alyssa Lesko, Kathleen H. Goss, Imge Hulur, Kenan Onel
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853(3):711-723
The Adenomatous Polyposis Coli (APC) tumor suppressor has been previously implicated in the control of apical–basal polarity; yet, the consequence of APC loss-of-function in epithelial polarization and morphogenesis has not been characterized. To t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886259e67dbe3acc46999b9962890fbd
Publikováno v:
Cancer Research. 78:4466-4466
Adenomatous Polyposis Coli (APC) is a well-known negative regulator of the Wnt pathway; however, it also regulates polarity proteins. Loss of apical-basal polarity disrupts several cellular processes including epithelial structure and intracellular s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdbf89750dd966cf977ea8670ca2a541
https://doi.org/10.1158/1538-7445.am2018-4466
https://doi.org/10.1158/1538-7445.am2018-4466
Autor:
Seth S. Martin, Jenn Quinn, Vasanth Sathiyakumar, Steven Jones, Alyssa Lesko, Robert Green, Kathleen Byrne, Emily Brown
Publikováno v:
Journal of Clinical Lipidology. 11:803
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b31bee23469fb774d748d8a01f6df2c
https://doi.org/10.1016/j.jacl.2017.04.052
https://doi.org/10.1016/j.jacl.2017.04.052
Publikováno v:
CLEO: 2014.
A graphene-based biopolymer is developed which exhibits saturable absorption and optical limiting behavior in the femtosecond and nanosecond regime respectively. Further this composite film when irradiated with nanosecond pulses indicates a damage th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d913496a62878b1abe2bb3fab2d9ce48
https://doi.org/10.1364/cleo_si.2014.sm3h.7
https://doi.org/10.1364/cleo_si.2014.sm3h.7
Autor:
Lewis E. Johnson, Stephanie J. Benight, Narayanan Venkat, Perry P. Yaney, Emily M. Heckman, Alyssa Lesko, Fahima Ouchen, James G. Grote
Publikováno v:
SPIE Proceedings.
This study highlights some of the effects of UV crosslinking of DNA-CTMA on its electrical and optical characteristics. The crosslinking of DNA-CTMA occurs via the photodimerization of attached coumarin moieties under UV irradiation. An exposure time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f45172fce11c0ef799392999679d793
https://doi.org/10.1117/12.2028361
https://doi.org/10.1117/12.2028361
Publikováno v:
Current drug targets. 15(1)
The Adenomatous Polyposis Coli (APC) tumor suppressor is most commonly mutated in colorectal cancers such as familial adenomatous polyposis (FAP); as well as many other epithelial cancers like breast, pancreatic, and lung cancer. APC mutations usuall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efb39877745b7409121cb34e7f02d98
https://pubmed.ncbi.nlm.nih.gov/24200292
https://pubmed.ncbi.nlm.nih.gov/24200292
Publikováno v:
Cancer Research. 76:3671-3671
The process of epithelial polarity is tightly regulated by multiple complexes including aPKC, PAR, and Crumbs proteins. Our laboratory has recently investigated loss of Adenomatous Polyposis Coli (APC) in the MDCK 3D culture system. We have observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb32490b97a04effc9dbc556faafaf51
https://doi.org/10.1158/1538-7445.am2016-3671
https://doi.org/10.1158/1538-7445.am2016-3671
Autor:
Brian A. Telek, Emily M. Fehrman Cory, Jack P. Lombardi, Alyssa Lesko, Fahima Ouchen, Emily M. Heckman, James G. Grote, Roberto S. Aga, Carrie M. Bartsch
Publikováno v:
SPIE Proceedings.
In this paper we present our current research in exploring a DNA biopolymer for photonics applications. A new processing technique has been adopted that employs a modified soxhlet-dialysis (SD) rinsing technique to completely remove excess ionic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8686d0de268ecb14d15a5e37e00fa0fa
https://doi.org/10.1117/12.930873
https://doi.org/10.1117/12.930873