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pro vyhledávání: '"Alyssa L. Crowder"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
The Forkhead box (FOX) family consists of at least 19 subgroups of transcription factors which are characterized by the presence of an evolutionary conserved ‘forkhead’ or ‘winged-helix’ DNA-binding domain. Despite having a conserved core DNA
Autor:
Rende Gu, Tegy J. Vadakkan, Andrew K. Groves, Tiantian Cai, Mary E. Dickinson, Alyssa L. Crowder, Victor G. Piazza, Rogers M. Brown, Chih-Wei Hsu
Publikováno v:
Developmental Biology. 414:72-84
The transcription factor Sox2 is both necessary and sufficient for the generation of sensory regions of the inner ear. It regulates expression of the Notch ligand Jag1 in prosensory progenitors, which signal to neighboring cells to up-regulate Sox2 a