Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alyssa K. Hartmann"'
Autor:
Tyler D Gavitt, Jessica L. Rouge, Steven M. Szczepanek, Arlind B Mara, Alyssa K. Hartmann, Shraddha S. Sawant
Publikováno v:
ACS Nano. 15:11192-11201
Allergic asthma is one of the leading chronic lung diseases of both children and adults worldwide, resulting in significant morbidity and mortality in affected individuals. Many patients have severe asthma, which is refractory to treatment, illustrat
Publikováno v:
Bioconjugate Chemistry. 31:1063-1069
Using a recently developed nucleic acid delivery platform, we demonstrate the effective delivery of metallodrug [AuIIIBr2(SSC-Inp-OEt)] (AP228; Inp = isonipecotic moiety), a hydrophobic, low solubility gold complex cytotoxic to cancer cells. It is sh
Publikováno v:
RSC Advances. 10:42349-42353
Intracellular trafficking and delivery of nucleic acids is an area of growing interest, particularly as it relates to therapeutic applications. Spectroscopic methods have been used to observe and quantitatively measure the delivery of oligonucleotide
Publikováno v:
Journal of materials chemistry. B. 8(26)
This work highlights a multifunctional nanoscale material which can effectively compartmentalize small molecules and biomolecules into a single, micellar structure with programmable degradation properties resulting in highly controllable release prop
Autor:
Jessica L. Rouge, Dominic F. Cairns-Gibson, Mark Q. Tolentino, Halle M. Barber, Joshua J. Santiana, Alyssa K. Hartmann
Publikováno v:
ChemBioChem. 19:1734-1739
Herein, we describe the characterization of a novel self-assembling and intracellular disassembling nanomaterial for nucleic acid delivery and targeted gene knockdown. By using a recently developed nucleic acid nanocapsule (NAN) formed from surfactan
Autor:
Joseph K. Awino, Joshua J. Santiana, Saketh Gudipati, Alyssa K. Hartmann, Dominic F. Cairns-Gibson, Jessica L. Rouge, Nicole Gomez
Publikováno v:
Journal of the American Chemical Society. 139:6278-6281
Herein we describe a nucleic acid functionalized nanocapsule in which nucleic acid ligands are assembled and disassembled in the presence of enzymes. The particles are fully degradable in response to esterases due to an embedded ester cross-linker in
Publikováno v:
ACS Symposium Series ISBN: 9780841233836
ACS Symposium Series
ACS Symposium Series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86711ccaf3f93ca037a49accd2eeb139
https://doi.org/10.1021/bk-2019-1309.ch003
https://doi.org/10.1021/bk-2019-1309.ch003
Autor:
Kazuo Sakurai, Marc A. Ilies, Jessica A. Kretzmann, David C. Luther, Marck Norret, Vincent M. Rotello, K. Swaminathan Iyer, Mathieu Berchel, Paul-Alain Jaffrès, Tony Le Gall, Tristan Montier, Joshua J. Santiana, Saketh Gudipati, Alyssa K. Hartmann, Jessica L. Rouge, Noriko Miyamoto, Shinichi Mochizuki, M. Rachèl Elzes, Guoying Si, Johan F. J. Engbersen, Jos M. J. Paulusse, Guoqing Wang, Yoshitsugu Akiyama, Naoki Kanayama, Tohru Takarada, Mizuo Maeda, Hung-Li Wang, De-Hao Tsai, Ajmeeta Sangtani, Megan E. Muroski, James B. Delehanty, Rajesh K. K. Sanku, Ozlem O. Karakus, Monica Ilies, Ahmed M. Shabana, Gurusamy Saravanakumar, Won Jong Kim, Long Binh Vong, Yukio Nagasaki, Safa Cyrus Fassihi, Rahmat Talukder, Reza Fassihi
Autor:
Yehia Mechref, Parvin Mirzaei, Alyssa K. Hartmann, Jingfu Zhao, Rui Zhu, Lauren G. Zacharias, Ehwang Song
Aberrant glycosylation has been linked to many different cancer types. The blood-brain barrier (BBB) is a region of the brain that regulates the entrance of ions, diseases, toxins, and so on. However, in breast cancer metastasis, the BBB fails to pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde883404b3b96572ad368c3a16a8a05
https://europepmc.org/articles/PMC5748158/
https://europepmc.org/articles/PMC5748158/
Autor:
Dominic F. Cairns-Gibson, Jessica L. Rouge, Halle M. Barber, Mark Q. Tolentino, Alyssa K. Hartmann, Joshua J. Santiana
Publikováno v:
ChemBioChem. 19:1664-1664