Výsledky vyhledávání - "Alyssa J. Weber"

Akademický článek

Enhancing endogenous levels of GLP1 dampens acute olanzapine induced perturbations in lipid and glucose metabolism

Autor: Kyle D. Medak, Alyssa J. Weber, Hesham Shamshoum, Greg L. McKie, Margaret K. Hahn, David C. Wright

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Olanzapine is a second-generation antipsychotic (SGA) used in the treatment of schizophrenia and several on- and off-label conditions. While effective in reducing psychoses, acute olanzapine treatment causes rapid hyperglycemia, insulin resistance, a

Externí odkaz: https://doaj.org/article/0448274fd60e464b8b6683d703bc0b97

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Reactive oxygen species-dependent regulation of pyruvate dehydrogenase kinase-4 in white adipose tissue

Autor: Pierre-Andre Barbeau, David C. Wright, Graham P. Holloway, Alyssa J. Weber, Logan K. Townsend

Publikováno v: Am J Physiol Cell Physiol

Reactive oxygen species (ROS) are important signaling molecules mediating the exercise-induced adaptations in skeletal muscle. Acute exercise also drives the expression of genes involved in reesterification and glyceroneogenesis in white adipose tiss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014058409b1ff63ebfc7a01d910ed5fe
https://doi.org/10.1152/ajpcell.00313.2019

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CHOP is dispensable for exercise-induced increases in GDF15

Autor: Logan K. Townsend, Kyle Medak, Alyssa J. Weber, Hana Dibe, Hesham Shamshoum, David C. Wright

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985). 132(2)

Growth differentiating factor-15 (GDF15) is expressed, and secreted, from a wide range of tissues and serves as a marker of cellular stress. A key transcriptional regulator of this hormone is the endoplasmic reticulum stress protein, CHOP (C/EBP homo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3f48858995b4cc715dbbb5a8206875
https://pubmed.ncbi.nlm.nih.gov/34913737

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What's up with WAT: attempting to mimic adipose tissue in vitro

Autor: Kyle D. Medak, Alyssa J. Weber, Logan K Townsend

Publikováno v: The Journal of Physiology. 600:725-726

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1b6b2502a4f0174a0b4dc564128afe
https://doi.org/10.1113/jp282344

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AMPK mediates energetic stress-induced liver GDF15

Autor: Bruce E. Kemp, Emily A. Day, Logan K Townsend, David C. Wright, Gregory R. Steinberg, Hesham Shamshoum, Alyssa J. Weber, Christopher G. R. Perry, Simon J. Shaw

Growth differentiating factor-15 (GDF15) is an emerging target for the treatment of obesity and metabolic disease partly due to its ability to suppress food intake. GDF15 expression and secretion are thought to be regulated by a cellular integrated s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c446c4d28df1f838cdac7d24f5e24da7
https://acuresearchbank.acu.edu.au/item/8w43z/ampk-mediates-energetic-stress-induced-liver-gdf15