Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alyssa J. Block"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Synthetic prions, generated de novo from minimal, non-infectious components, cause bona fide prion disease in animals. Transmission of synthetic prions to hosts expressing syngeneic PrPC results in extended, variable incubation periods and i
Externí odkaz:
https://doaj.org/article/4b8aefa4aa9b4019a521dd10acf81e9e
Autor:
Alyssa J Block, Ronald A Shikiya, Thomas E Eckland, Anthony E Kincaid, Ryan W Walters, Jiyan Ma, Jason C Bartz
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009765 (2021)
Prions are comprised solely of PrPSc, the misfolded self-propagating conformation of the cellular protein, PrPC. Synthetic prions are generated in vitro from minimal components and cause bona fide prion disease in animals. It is unknown, however, if
Externí odkaz:
https://doaj.org/article/2bb711d9194349748584815d38fb507f
Autor:
Alyssa J. Block, Jason C. Bartz
Publikováno v:
Cell and Tissue Research. 392:113-133
Autor:
Ryan W. Walters, Alyssa J. Block, Anthony E. Kincaid, Ronald A. Shikiya, Jason C. Bartz, Jiyan Ma, Thomas E. Eckland
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 7, p e1009765 (2021)
PLoS Pathogens, Vol 17, Iss 7, p e1009765 (2021)
Prions are comprised solely of PrPSc, the misfolded self-propagating conformation of the cellular protein, PrPC. Synthetic prions are generated in vitro from minimal components and cause bona fide prion disease in animals. It is unknown, however, if
Publikováno v:
Prog Mol Biol Transl Sci
Prions are a self-propagating misfolded conformation of a cellular protein. Prions are found in several eukaryotic organisms with mammalian prion diseases encompassing a wide range of disorders. The first recognized prion disease, the transmissible s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcddd0f66bf2b00878b0911803d99ff
https://doi.org/10.1016/bs.pmbts.2020.07.001
https://doi.org/10.1016/bs.pmbts.2020.07.001
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011632 (2023)
Prion diseases are a group of inevitably fatal neurodegenerative disorders affecting numerous mammalian species, including Sapiens. Prions are composed of PrPSc, the disease specific conformation of the host encoded prion protein. Prion strains are o
Externí odkaz:
https://doaj.org/article/d0be852e849b414c812358735bc2fef9