Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alyssa J Lawler"'
Autor:
Alyssa J Lawler, Easwaran Ramamurthy, Ashley R Brown, Naomi Shin, Yeonju Kim, Noelle Toong, Irene M Kaplow, Morgan Wirthlin, Xiaoyu Zhang, BaDoi N Phan, Grant A Fox, Kirsten Wade, Jing He, Bilge Esin Ozturk, Leah C Byrne, William R Stauffer, Kenneth N Fish, Andreas R Pfenning
Publikováno v:
eLife, Vol 11 (2022)
Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations within heterogeneous tissue. Available approaches for engineering-targeted technologies for new neuron subtype
Externí odkaz:
https://doaj.org/article/95df1d9dbb294e8484fc20dc51bd5aec
Autor:
Irene M. Kaplow, Daniel E. Schäffer, Morgan E. Wirthlin, Alyssa J. Lawler, Ashley R. Brown, Michael Kleyman, Andreas R. Pfenning
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-23 (2022)
Abstract Background Evolutionary conservation is an invaluable tool for inferring functional significance in the genome, including regions that are crucial across many species and those that have undergone convergent evolution. Computational methods
Externí odkaz:
https://doaj.org/article/7743500a21774d7b96b13f84255422c2
Autor:
Ashley R. Brown, Grant A. Fox, Irene M. Kaplow, Alyssa J. Lawler, BaDoi N. Phan, Morgan E. Wirthlin, Easwaran Ramamurthy, Gemma E. May, Ziheng Chen, Qiao Su, C. Joel McManus, Andreas R. Pfenning
Genetic studies are rapidly identifying non-protein-coding human disease-associated loci. Understanding the regulatory mechanisms underlying these loci remains a challenge because the causal variants and the tissues in which they act are often unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20d3fd569187d296363d78bc2809699e
https://doi.org/10.1101/2022.11.23.517755
https://doi.org/10.1101/2022.11.23.517755
Autor:
Michael Kleyman, Andreas R. Pfenning, Alyssa J. Lawler, Easwaran Ramamurthy, Irene M. Kaplow, Ashley R. Brown, Morgan Wirthlin, BaDoi N. Phan, Chaitanya Srinivasan
Publikováno v:
The Journal of Neuroscience
Recent large genome-wide association studies (GWAS) have identified multiple confident risk loci linked to addiction-associated behavioral traits. Genetic variants linked to addiction-associated traits lie largely in non-coding regions of the genome,
Autor:
Alyssa J Lawler, Easwaran Ramamurthy, Ashley R Brown, Naomi Shin, Yeonju Kim, Noelle Toong, Irene M Kaplow, Morgan Wirthlin, Xiaoyu Zhang, BaDoi N Phan, Grant A Fox, Kirsten Wade, Jing He, Bilge Esin Ozturk, Leah C Byrne, William R Stauffer, Kenneth N Fish, Andreas R Pfenning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af02d8d0949a0762b576362bce53291
https://doi.org/10.7554/elife.69571.sa2
https://doi.org/10.7554/elife.69571.sa2
Autor:
Alyssa J Lawler, Easwaran Ramamurthy, Ashley R Brown, Naomi Shin, Yeonju Kim, Noelle Toong, Irene M Kaplow, Morgan Wirthlin, Xiaoyu Zhang, BaDoi N Phan, Grant A Fox, Kirsten Wade, Jing He, Bilge Esin Ozturk, Leah C Byrne, William R Stauffer, Kenneth N Fish, Andreas R Pfenning
Publikováno v:
eLife. 11
Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations within heterogeneous tissue. Available approaches for engineering-targeted technologies for new neuron subtype
Autor:
Grant Fox, Andreas R. Pfenning, Xiaoyu Zhang, Noelle Toong, Alyssa J. Lawler, Yeonju Kim, Ashley R. Brown, Easwaran Ramamurthy, Irene M. Kaplow, Morgan Wirthlin, Naomi Shin
Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations, enabling characterization of their roles in behavior and in disease states. Available approaches for engineer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d377f66501c048b0c9e4d3a85668eba
https://doi.org/10.1101/2021.04.15.439984
https://doi.org/10.1101/2021.04.15.439984
Autor:
Andrew Clugston, Andrew J. Bodnar, Débora M. Cerqueira, Alyssa J. Lawler, Boggs K, Yu Leng Phua, Jacqueline Ho, Andreas R. Pfenning, Dennis Kostka
Mammalian nephrons originate from a population of nephron progenitor cells (NPCs), and it is known that NPCs’ transcriptomes change throughout nephrogenesis during healthy kidney development. To characterize chromatin accessibility and microRNA (mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::295edfd75549542a978ac930b7757b6e
https://doi.org/10.1101/2021.03.05.434138
https://doi.org/10.1101/2021.03.05.434138
Autor:
Ashley R. Brown, Daniel E. Schäffer, Andreas R. Pfenning, Irene M. Kaplow, Alyssa J. Lawler, Michael Kleyman, Morgan Wirthlin
Background Evolutionary conservation is an invaluable tool for inferring functional significance in the genome, including regions that are crucial across many species and those that have undergone convergent evolution. Computational methods to test f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f374cc24bfe1fa8b458f9c55c9dd7828
https://doi.org/10.1101/2020.12.04.410795
https://doi.org/10.1101/2020.12.04.410795
Autor:
Andreas R. Pfenning, BaDoi N. Phan, Alyssa J. Lawler, William R. Stauffer, Ashley R. Brown, Jing He, Morgan Wirthlin, Irene M. Kaplow
In mammals, fine motor control is essential for skilled behavior, and is subserved by specialized subdivisions of the primary motor cortex (M1) and other components of the brain’s motor circuitry. We profiled the epigenomic state of several compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbdce4bd72a4ce6339bb13d5c2d107ee
https://doi.org/10.1101/2020.10.27.356733
https://doi.org/10.1101/2020.10.27.356733