Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alyssa Hoover"'
Autor:
Whitney Barham, Fiona E. Yull, Demetra Hufnagel, Evan B. Glass, Whitney Harris, Dineo Khabele, Esther Liu, Alyssa Hoover, Marta A. Crispens, Andrew J. Wilson, Todd D. Giorgio, Kennady K. Bullock
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
BMC Cancer
BMC Cancer
Background New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes represents an important therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f00bb5a85191b9d46b1eb8d2f8b8a4
http://link.springer.com/article/10.1186/s12885-020-07450-8
http://link.springer.com/article/10.1186/s12885-020-07450-8
Autor:
Alyssa R. Merkel, Todd D. Giorgio, Evan B. Glass, Dominique Parker, Alyssa Hoover, Fiona E. Yull, Julie A. Rhoades, Kennady K. Bullock, Richard Maynard, Andrew J. Wilson
Publikováno v:
Cancer Research. 81:2728-2728
Tumor associated macrophages (TAMs) often exist in high densities in breast tumors and are associated with adverse clinical outcomes. TAM repolarization as a strategy to shift the breast cancer microenvironment from immunosuppressive to immunostimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cac4a1db5e822b5c32a91e961e5bf66
https://doi.org/10.1158/1538-7445.am2021-2728
https://doi.org/10.1158/1538-7445.am2021-2728
Publikováno v:
Clinical Cancer Research. 25:TMIM-085
BACKGROUND: Ovarian cancer is the most lethal gynecologic malignancy. While women with BRCA deficient tumors show sensitivity to PARP inhibitors (PARPi), new treatment options are urgently needed for patients with PARPi-resistant tumors. An emerging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b28a46f97fcbb22b6018793f5efccdd
https://doi.org/10.1158/1557-3265.ovcasymp18-tmim-085
https://doi.org/10.1158/1557-3265.ovcasymp18-tmim-085
Autor:
Zahra Mirafzali, Whitney Harris, Todd D. Giorgio, Alyssa Hoover, Fiona E. Yull, Andrew J. Wilson, Evan B. Glass
Publikováno v:
Cancer Research. 79:4138-4138
It is recognized that modulation of macrophage phenotypes within the tumor microenvironment has the potential to achieve anti-tumor outcomes. However, formulating a strategy to achieve the benefits of such an approach in a cell-specific manner while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d12c702b06738be97215f98729494a5a
https://doi.org/10.1158/1538-7445.am2019-4138
https://doi.org/10.1158/1538-7445.am2019-4138
Autor:
Todd D. Giorgio, Fiona E. Yull, Whitney Harris, Esther Liu, Whitney Barham, Oleg Tikhomirov, Dineo Khabele, Alyssa Hoover, Andrew J. Wilson, Zahra Mirafzahli
Publikováno v:
Cancer Research. 78:4711-4711
While it is known that nuclear factor κ-B (NF-κB) signaling within macrophages regulates expression of downstream targets that can mediate either pro- or antitumor functions, the mechanisms that define predominant characteristics are not well under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1b863ada47db98100a55bcee17000b7
https://doi.org/10.1158/1538-7445.am2018-4711
https://doi.org/10.1158/1538-7445.am2018-4711
Publikováno v:
Cancer Research. 78:626-626
Background: Ovarian cancer is the most lethal gynecologic malignancy. While women with BRCA-deficient tumors show sensitivity to PARP inhibitors (PARPi), new treatment options are needed for PARPi-resistant tumors. An emerging strategy to improve PAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e49870174d8638172a85e7785fb31746
https://doi.org/10.1158/1538-7445.am2018-626
https://doi.org/10.1158/1538-7445.am2018-626