Speed and Cumulative Responses According to Body Regions in Patients with Moderate-to-Severe Plaque Psoriasis Treated with Ixekizumab (Interleukin-17A Antagonist) versus Guselkumab (Interleukin-23p19 Inhibitor)

Autor: Melinda Gooderham, Ronald Vender, Jeffrey Crowley, H. Chih-Ho Hong, Meghan Feely, Alyssa Garrelts, Kyoungah See, Bruce Konicek, Lawrence Green

Publikováno v: Dermatology and Therapy, Vol 14, Iss 2, Pp 441-451 (2024)

Abstract Introduction When assessing the effect of a therapy for psoriasis (PsO), it is important to consider speed of response and cumulative response. However, responses among biologics may differ by body regions. This post hoc analysis compares sp

Externí odkaz: https://doaj.org/article/f00c3bb6c4ff40e9a728bb090f968f07

Network meta-analyses comparing the efficacy of biologic treatments for achieving complete resolution of nail psoriasis at 24–28 and 48–52 weeks

Autor: Alexander Egeberg, Lars Erik Kristensen, Luis Puig, Phoebe Rich, Saxon D. Smith, Alyssa Garrelts, Kyoungah See, Thorsten Holzkaemper, Konstantinos Fotiou, Christopher Schuster

Publikováno v: Journal of Dermatological Treatment, Vol 34, Iss 1 (2023)

Background Available network meta-analyses (NMAs) comparing the efficacy of biologics in nail psoriasis (NP) have not included recently approved biologics such as bimekizumab nor have they provided comparisons up to 1 year. Objective We conducted two

Externí odkaz: https://doaj.org/article/5362c29498f147efbcd364accd7a6767

Number Needed to Treat Network Meta-Analysis to Compare Biologic Drugs for Moderate-to-Severe Psoriasis

Autor: Craig L. Leonardi, Kyoungah See, Russel Burge, Zhuoer Sun, Ying Zhang, Lotus Mallbris, Alyssa Garrelts, Richard B. Warren

Publikováno v: Advances in Therapy. 39:2256-2269

Number needed to treat (NNT) estimates are a practical metric to help identify the most effective therapies. Our objective is to compare 11 biologic drugs for moderate-to-severe psoriasis in terms of NNT.The NNT data were obtained from a Bayesian net

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c4490b91396ebbf959d491cee1b394
https://doi.org/10.1007/s12325-022-02065-w

Epidemiology of psoriasis in hard-to-treat body locations: data from the Danish skin cohort

Autor: Alexander Egeberg, Russel Burge, Alyssa Garrelts, Kyoungah See

Publikováno v: BMC Dermatology, Vol 20, Iss 1, Pp 1-8 (2020)
BMC Dermatology

Background Having psoriasis in hard-to-treat areas, i.e. the scalp, face, palms, soles, nails, and genitals, respectively, can impair patients’ quality of life. We investigated the prevalence of hard-to-treat body locations of psoriasis, and descri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e3207ec4d4af3b0cf2609677aa08e2
http://link.springer.com/article/10.1186/s12895-020-00099-7

Rapid Response of Biologic Treatments of Moderate-to-Severe Plaque Psoriasis: A Comprehensive Investigation Using Bayesian and Frequentist Network Meta-analyses

Autor: Alyssa Garrelts, Alan Brnabic, Alexander Egeberg, Ying Zhang, Kyoungah See, Richard B. Warren, Gaia Gallo, Russel Burge

Publikováno v: Dermatology and Therapy, Vol 10, Iss 1, Pp 73-86 (2019)
Dermatology and Therapy
Warren, R B, See, K, Burge, R, Zhang, Y, Brnabic, A, Gallo, G, Garrelts, A & Egeberg, A 2020, ' Rapid Response of Biologic Treatments of Moderate-to-Severe Plaque Psoriasis : A Comprehensive Investigation Using Bayesian and Frequentist Network Meta-analyses ', Dermatology and Therapy, vol. 10, no. 1, pp. 73-86 . https://doi.org/10.1007/s13555-019-00337-y

Introduction Rapid improvement of psoriasis is valued by patients and should be considered to be an important factor in treatment selection. We investigated Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) response r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3740aec8bb29bea9470e190cc060aa
http://link.springer.com/article/10.1007/s13555-019-00337-y