Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Alyssa E. Barry"'
Autor:
Madeline G. Dans, Coralie Boulet, Gabrielle M. Watson, William Nguyen, Jerzy M. Dziekan, Cindy Evelyn, Kitsanapong Reaksudsan, Somya Mehra, Zahra Razook, Niall D. Geoghegan, Michael J. Mlodzianoski, Christopher Dean Goodman, Dawson B. Ling, Thorey K. Jonsdottir, Joshua Tong, Mufuliat Toyin Famodimu, Mojca Kristan, Harry Pollard, Lindsay B. Stewart, Luke Brandner-Garrod, Colin J. Sutherland, Michael J. Delves, Geoffrey I. McFadden, Alyssa E. Barry, Brendan S. Crabb, Tania F. de Koning-Ward, Kelly L. Rogers, Alan F. Cowman, Wai-Hong Tham, Brad E. Sleebs, Paul R. Gilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract With resistance to most antimalarials increasing, it is imperative that new drugs are developed. We previously identified an aryl acetamide compound, MMV006833 (M-833), that inhibited the ring-stage development of newly invaded merozoites. H
Externí odkaz:
https://doaj.org/article/ff89181888414cdebed058704ff392b1
Autor:
Madeline G. Dans, Coralie Boulet, Gabrielle M. Watson, William Nguyen, Jerzy M. Dziekan, Cindy Evelyn, Kitsanapong Reaksudsan, Somya Mehra, Zahra Razook, Niall D. Geoghegan, Michael J. Mlodzianoski, Christopher Dean Goodman, Dawson B. Ling, Thorey K. Jonsdottir, Joshua Tong, Mufuliat Toyin Famodimu, Mojca Kristan, Harry Pollard, Lindsay B. Stewart, Luke Brandner-Garrod, Colin J. Sutherland, Michael J. Delves, Geoffrey I. McFadden, Alyssa E. Barry, Brendan S. Crabb, Tania F. de Koning-Ward, Kelly L. Rogers, Alan F. Cowman, Wai-Hong Tham, Brad E. Sleebs, Paul R. Gilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/36bf3afec36e4aac961dcc7fb75d1e5e
Autor:
Mahamoudou Toure, Jeffrey G Shaffer, Daouda Sanogo, Soumba Keita, Moussa Keita, Fousseyni Kane, Bourama Traore, Djeneba Dabitao, Aissata Kone, Cheick Oumar Doumbia, Joseph Keating, Joshua Yukich, Helle H Hansson, Alyssa E Barry, Mahamadou Diakité, Michael Alifrangis, Seydou Doumbia
Publikováno v:
JMIR Research Protocols, Vol 13, p e51660 (2024)
BackgroundSeasonal malaria chemoprevention (SMC) is recommended by the World Health Organization for the sub-Sahel region in sub-Saharan Africa for preventing malaria in children 3 months old to younger than 5 years. Since 2016, the Malian National M
Externí odkaz:
https://doaj.org/article/722056e59a2d4a14816a3411da7e8a48
Autor:
Myo T. Naung, Elijah Martin, Wilson Wong, Zahra Razook, Digjaya Utama, Andrew J. Guy, Shannon Takala Harrison, Alan F. Cowman, Enmoore Lin, Benson Kiniboro, Moses Laman, Ivo Mueller, Alyssa E. Barry
Publikováno v:
Frontiers in Parasitology, Vol 2 (2023)
Plasmodium falciparum Reticulocyte Binding Protein Homologue (RH5), a leading malaria vaccine candidate, is essential for erythrocyte invasion by the parasite, interacting with the human host receptor, basigin. RH5 has a small number of polymorphisms
Externí odkaz:
https://doaj.org/article/9c0eded36cbd4ed89c86f1699d2705be
Autor:
Madeline G Dans, Henni Piirainen, William Nguyen, Sachin Khurana, Somya Mehra, Zahra Razook, Niall D Geoghegan, Aurelie T Dawson, Sujaan Das, Molly Parkyn Schneider, Thorey K Jonsdottir, Mikha Gabriela, Maria R Gancheva, Christopher J Tonkin, Vanessa Mollard, Christopher Dean Goodman, Geoffrey I McFadden, Danny W Wilson, Kelly L Rogers, Alyssa E Barry, Brendan S Crabb, Tania F de Koning-Ward, Brad E Sleebs, Inari Kursula, Paul R Gilson
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002066 (2023)
With emerging resistance to frontline treatments, it is vital that new antimalarial drugs are identified to target Plasmodium falciparum. We have recently described a compound, MMV020291, as a specific inhibitor of red blood cell (RBC) invasion, and
Externí odkaz:
https://doaj.org/article/d4ae40a3c3394669ac6efd4a149b5ec0
Autor:
Dulcie Lautu-Gumal, Zahra Razook, Tamarah Koleala, Elma Nate, Samuel McEwen, Diana Timbi, Manuel W. Hetzel, Evelyn Lavu, Nakapi Tefuarani, Leo Makita, James Kazura, Ivo Mueller, William Pomat, Moses Laman, Leanne J. Robinson, Alyssa E. Barry
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss , Pp 188-193 (2021)
Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene (Pfk13) that are associated with delayed parasite clearance hav
Externí odkaz:
https://doaj.org/article/198619d3abfe4e2bbb6d7c0403e93cc4
Autor:
Katherine O’Flaherty, Win Han Oo, Sophie G. Zaloumis, Julia C. Cutts, Kyaw Zayar Aung, Myat Mon Thein, Damien R. Drew, Zahra Razook, Alyssa E. Barry, Naanki Parischa, Nyi Nyi Zaw, Htin Kyaw Thu, Aung Thi, Wai Yan Min Htay, Aung Paing Soe, Julie A. Simpson, James G. Beeson, Paul A. Agius, Freya J. I. Fowkes
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background In the Greater Mekong Subregion (GMS), current malaria surveillance strategies rely on a network of village health volunteers (VHVs) reporting the results of rapid diagnostic tests (RDTs), known to miss many asymptomatic infection
Externí odkaz:
https://doaj.org/article/d938c3430c7145499056a612335bdf88
Autor:
Abebe A. Fola, Eline Kattenberg, Zahra Razook, Dulcie Lautu-Gumal, Stuart Lee, Somya Mehra, Melanie Bahlo, James Kazura, Leanne J. Robinson, Moses Laman, Ivo Mueller, Alyssa E. Barry
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-15 (2020)
Abstract Background Genomic surveillance of malaria parasite populations has the potential to inform control strategies and to monitor the impact of interventions. Barcodes comprising large numbers of single nucleotide polymorphism (SNP) markers are
Externí odkaz:
https://doaj.org/article/47c2a8a7586e429bb5e17b5cb1a7b59f
Autor:
Johanna H. Kattenberg, Dulcie L. Gumal, Maria Ome-Kaius, Benson Kiniboro, Matthew Philip, Shadrach Jally, Bernadine Kasian, Naomi Sambale, Peter M. Siba, Stephan Karl, Alyssa E. Barry, Ingrid Felger, James W. Kazura, Ivo Mueller, Leanne J. Robinson
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-18 (2020)
Abstract Background In the past decade, national malaria control efforts in Papua New Guinea (PNG) have received renewed support, facilitating nationwide distribution of free long-lasting insecticidal nets (LLINs), as well as improvements in access t
Externí odkaz:
https://doaj.org/article/9607af3bb0814c2aa440e512cc6cb2e8
Autor:
Myo T Naung, Elijah Martin, Jacob Munro, Somya Mehra, Andrew J Guy, Moses Laman, G L Abby Harrison, Livingstone Tavul, Manuel Hetzel, Dominic Kwiatkowski, Ivo Mueller, Melanie Bahlo, Alyssa E Barry
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009801 (2022)
Investigation of the diversity of malaria parasite antigens can help prioritize and validate them as vaccine candidates and identify the most common variants for inclusion in vaccine formulations. Studies of vaccine candidates of the most virulent hu
Externí odkaz:
https://doaj.org/article/e70090b6591344ce912303e8a57e60a5