Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alyson Peel"'
Autor:
Veronica Galvan, Surita Banwait, Patricia Spilman, Olivia F. Gorostiza, Alyson Peel, Marina Ataie, Danielle Crippen, Wei Huang, Gurleen Sidhu, Hidenori Ichijo, Dale E. Bredesen
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 1, Pp 65-75 (2007)
The amyloid precursor protein (APP) is a type I transmembrane protein translocated to neuronal terminals, whose function is still unknown. The C-terminus of APP mediates its interaction with cellular adaptor and signaling proteins, some of which sign
Externí odkaz:
https://doaj.org/article/8fbd6bc8bf974d6484890cb67c2ac3ee
Autor:
Kunlin Jin, Yunjuan Sun, Lin Xie, Xiao Ou Mao, Joycelyn Childs, Alyson Peel, Anna Logvinova, Surita Banwait, David A. Greenberg
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 2, Pp 366-374 (2005)
Cell replacement therapy may have the potential to promote brain repair and recovery after stroke. To compare how focal cerebral ischemia affects the entry, migration, and phenotypic features of neural precursor cells transplanted by different routes
Externí odkaz:
https://doaj.org/article/cfa7b0581d694ebab6aaa369fa7a7ee1
Autor:
Dale E. Bredesen, Veronica Galvan, Olivia Gorostiza, Gurleen Sidhu, Wei Huang, Hidenori Ichijo, Surita Banwait, Marina Ataie, Patricia Spilman, Danielle Crippen, Alyson Peel
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 1, Pp 65-75 (2007)
The amyloid precursor protein (APP) is a type I transmembrane protein translocated to neuronal terminals, whose function is still unknown. The C-terminus of APP mediates its interaction with cellular adaptor and signaling proteins, some of which sign
Autor:
David A. Greenberg, Kunlin Jin, Yunjuan Sun, Xiaojuan Wang, Anna Logvinova, Jocelyn Childs, Lin Xie, Xiao Ou Mao, Alyson Peel
Publikováno v:
Neurobiology of Aging. 26:275-278
Neuroglobin (Ngb), a recently discovered O2-binding heme protein related to hemoglobin and myoglobin, protects neurons from hypoxic-ischemic injury in vitro and in vivo. In immunostained mouse brain sections, we found widespread expression of Ngb pro
Publikováno v:
NeuroMolecular Medicine. 5:205-218
The two predominant pathological concomitants of Alzheimer's disease (AD) are senile plaques and neurofibrillary tangles. Although many biochemical studies have addressed the composition and formation of these AD hallmarks, very little is known about
Autor:
Alyson Peel, Dale E. Bredesen
Publikováno v:
Neurobiology of Disease, Vol 14, Iss 1, Pp 52-62 (2003)
Accumulation of amyloid beta peptides (Abeta) in the brain, which is a hallmark of Alzheimer's disease (AD), is associated with progressive damage to neuronal processes resulting in extensive neuritic dystrophy. This process may contribute to cogniti
Autor:
Lin Xie, Yunjuan Sun, David A. Greenberg, Sophie Batteur, Kunlin Jin, Xiao Ou Mao, Alyson Peel
Publikováno v:
Molecular and Cellular Neuroscience. 24:171-189
Pathological processes, including cerebral ischemia, can enhance neurogenesis in the adult brain, but the fate of the newborn neurons that are produced and their role in brain repair are obscure. To determine if ischemia-induced neuronal proliferatio
Publikováno v:
Proceedings of the National Academy of Sciences. 100:3497-3500
Neuroglobin (Ngb) is an O 2 -binding protein localized to cerebral neurons of vertebrates, including humans. Its physiological role is unknown but, like hemoglobin, myoglobin, and cytoglobin/histoglobin, it may transport O 2 , detoxify reactive oxyge
Autor:
Thierry Berney, R. Damaris Molano, Antonello Pileggi, Pierre Cattan, Caterina Vizzardelli, Elizabeth S. Fenjves, Camillo Ricordi, Alyson Peel, Chris Fraker, Luca Inverardi
Publikováno v:
Xenotransplantation. 9:14-24
Neonatal porcine islets are characterized by reproducible isolation success and high yields, sizable advantages over adult islets. In this work we have analyzed selected phenotypic and functional characteristics of porcine neonatal islets relevant to
Autor:
Ram V. Rao, Michael R. Hayden, Lisa M. Ellerby, Dale E. Bredesen, Alyson Peel, Barbara A. Cottrell
Publikováno v:
Human Molecular Genetics. 10:1531-1538
Fourteen neurological diseases have been associated with the expansion of trinucleotide repeat regions. These diseases have been categorized into those that give rise to the translation of toxic polyglutamine proteins and those that are untranslated.