A randomized, double-blind, placebo-controlled proof-of-concept study of ondansetron for bipolar and related disorders and alcohol use disorder

Autor: E. Sherwood Brown, Collette Bice, Alyson Nakamura, Jayme M. Palka, Elena I. Ivleva, Zena Patel, Meagan McArdle, Markey C. McNutt, Shane Tipton, Traci Holmes

Publikováno v: European Neuropsychopharmacology. 43:92-101

Bipolar disorder is associated with high rates of alcohol use disorder. However, little is known about the treatment of this dual diagnosis population. Previous studies suggest that ondansetron decreases alcohol use, particularly in people with speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be49d4e4deb21e8c169cd7bc44b1b1aa
https://doi.org/10.1016/j.euroneuro.2020.12.006

A Randomized, Double-Blind, Placebo-Controlled Trial of Escitalopram in Patients with Asthma and Major Depressive Disorder

Autor: Elena I. Ivleva, Alyson Nakamura, Alexandra Kulikova, Erin Van Enkevort, Prabha Sunderajan, Nasreen Sayed, David A. Khan, Traci Holmes, Bruce G. Bender, E. Sherwood Brown

Publikováno v: The Journal of Allergy and Clinical Immunology: In Practice. 6:1604-1612

Background Depression is common in asthma and is associated with poor outcomes. However, antidepressant therapy in depressed patients with asthma has been the topic of little research. Objective This study examined the impact of antidepressant treatm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fafeab009a9742a36ca1f9d12719d6
https://doi.org/10.1016/j.jaip.2018.01.010

Multivariate Association of Child Depression and Anxiety With Asthma Outcomes

Autor: Alyson Nakamura, Tressa Lloyd, Josseline Lopez, Shane Tipton, Raymond Chankalal, E. Sherwood Brown, Ray J. Pak, Quratulain Humayun, Alexandra Kulikova, Beatrice L. Wood, Bruce D. Miller, Donna Persaud, Heather K. Lehman, Dave A. Khan, Zena Patel, Elena I. Ivleva, M. Seth Owitz, Savitoj Kaur, Anna Antony, Michael S. Adragna, Karen Allen, Jasmine Tiro

Publikováno v: J Allergy Clin Immunol Pract

BACKGROUND: Pediatric asthma is associated with increased health services utilization, missed school days and diminished quality of life. Children with asthma also report more frequent depressive and anxiety symptoms than non-asthmatic children, whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30aef3a38733a4a279086eadd1ef2916
https://doi.org/10.1016/j.biopsych.2021.02.838

A randomized, double-blind, placebo-controlled trial of lamotrigine for prescription corticosteroid effects on the human hippocampus

Autor: Michael A. Yassa, E. Sherwood Brown, Elena I. Ivleva, Alan B. Frol, David A. Khan, Bruce S. McEwen, Erin Van Enkevort, Jared M. Roberts, Alyson Nakamura, Nasreen Sayed, Alexandra Kulikova, Miguel A. Vazquez, Prabha Sunderajan, Traci Holmes, Changho Choi, Nicholas J. Tustison

Publikováno v: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, vol 29, iss 3
Eur Neuropsychopharmacol

In animals, stress and corticosteroid excess are associated with decreases in memory performance and hippocampal volume that may be prevented with agents that decrease glutamate release. Humans also demonstrate changes in memory and hippocampus with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3a173de4854809dd3ebcc956885220
https://escholarship.org/uc/item/3c90p4wb

A pilot study of brexpiprazole for bipolar depression

Autor: E. Sherwood Brown, Neusha Khaleghi, Alyson Nakamura, Erin Van Enkevort, Traci Holmes, Elena I. Ivleva, Brittany L. Mason, Chastity Escalante

Publikováno v: Journal of affective disorders. 249

Background Past studies suggest that brexpiprazole is an effective adjunctive treatment for major depressive disorder and schizophrenia; however, no studies have examined brexpiprazole for bipolar depression. In this study, we examined the effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f023358a6c29565e13bdeec5a1eebe1
https://pubmed.ncbi.nlm.nih.gov/30802696