Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alyson L Dickson"'
Autor:
Lan Jiang, Ge Liu, Annette Oeser, Andrea Ihegword, Alyson L Dickson, Laura L Daniel, Adriana M Hung, Nancy J Cox, Cecilia P Chung, Wei-Qi Wei, C Michael Stein, Qiping Feng
Publikováno v:
eLife, Vol 12 (2023)
Background: Two risk variants in the apolipoprotein L1 gene (APOL1) have been associated with increased susceptibility to sepsis in Black patients. However, it remains unclear whether APOL1 high-risk genotypes are associated with occurrence of either
Externí odkaz:
https://doaj.org/article/3baa0f4a81db461eb55066a00231d9f0
Autor:
Jonathan D. Mosley, John P. Shelley, Alyson L. Dickson, Jacy Zanussi, Laura L. Daniel, Neil S. Zheng, Lisa Bastarache, Wei-Qi Wei, Mingjian Shi, Gail P. Jarvik, Elisabeth A. Rosenthal, Atlas Khan, Alborz Sherafati, Iftikhar J. Kullo, Theresa L. Walunas, Joseph Glessner, Hakon Hakonarson, Nancy J. Cox, Dan M. Roden, Stephan G. Frangakis, Brett Vanderwerff, C. Michael Stein, Sara L. Van Driest, Scott C. Borinstein, Xiao-Ou Shu, Matthew Zawistowski, Cecilia P. Chung, Vivian K. Kawai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Polygenic variation unrelated to disease contributes to interindividual variation in baseline white blood cell (WBC) counts, but its clinical significance is uncharacterized. We investigated the clinical consequences of a genetic predisposit
Externí odkaz:
https://doaj.org/article/aac9cb1b2aa64c909fbdd66e307ed326
Autor:
Chao Yan, Monika E. Grabowska, Alyson L. Dickson, Bingshan Li, Zhexing Wen, Dan M. Roden, C. Michael Stein, Peter J. Embí, Josh F. Peterson, QiPing Feng, Bradley A. Malin, Wei-Qi Wei
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-6 (2024)
Abstract Drug repurposing represents an attractive alternative to the costly and time-consuming process of new drug development, particularly for serious, widespread conditions with limited effective treatments, such as Alzheimer’s disease (AD). Em
Externí odkaz:
https://doaj.org/article/5a14ed00b9d54394bba0dc3ee3901fe9
Autor:
Lan Jiang, Srushti Gangireddy, Alyson L. Dickson, Yi Xin, Chao Yan, Vivian Kawai, Nancy J. Cox, MacRae F. Linton, Wei-Qi Wei, C. Michael Stein, QiPing Feng
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 6, Pp 100569- (2024)
Hypertriglyceridemia (HTG) is a common cardiovascular risk factor characterized by elevated triglyceride (TG) levels. Researchers have assessed the genetic factors that influence HTG in studies focused predominantly on individuals of European ancestr
Externí odkaz:
https://doaj.org/article/da16de995003474fb80d5f0f18e3d4e6
Autor:
Lan Jiang, V. Eric Kerchberger, Christian Shaffer, Alyson L. Dickson, Michelle J. Ormseth, Laura L. Daniel, Barbara G. Carranza Leon, Nancy J. Cox, Cecilia P. Chung, Wei-Qi Wei, C. Michael Stein, QiPing Feng
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Introduction Infectious diseases are common causes of morbidity and mortality worldwide. Susceptibility to infection is highly heritable; however, little has been done to identify the genetic determinants underlying common infectious disease
Externí odkaz:
https://doaj.org/article/fbb8510073534dcdbf972a289871a537
Autor:
Meghan A. Corriere, Alyson L. Dickson, Laura L. Daniel, Puran Nepal, Kathi Hall, W. Dale Plummer, William D. Dupont, Katherine T. Murray, C. Michael Stein, Wayne A. Ray, Cecilia P. Chung
Publikováno v:
The Clinical Journal of Pain. 39:203-208
Autor:
Minoo Bagheri, Cecilia P. Chung, Alyson L. Dickson, Sara L. Van Driest, Scott C. Borinstein, Jonathan D. Mosley
Publikováno v:
Blood Advances. 7:406-409
Autor:
Ge Liu, Lan Jiang, V. Eric Kerchberger, Annette Oeser, Andrea Ihegword, Alyson L. Dickson, Laura L. Daniel, Christian Shaffer, MacRae F. Linton, Nancy Cox, Cecilia P. Chung, Wei‐Qi Wei, C. Michael Stein, QiPing Feng
Publikováno v:
Clinical and Translational Science. 16:489-501
Autor:
Wayne A. Ray, Cecilia P. Chung, C. Michael Stein, Walter Smalley, Eli Zimmerman, William D. Dupont, Adriana M. Hung, James R. Daugherty, Alyson L. Dickson, Katherine T. Murray
Publikováno v:
Annals of Internal Medicine.
Autor:
Alyson L. Dickson, Laura L. Daniel, Elise Jackson, Jacy Zanussi, Wenjian Yang, W. Dale Plummer, William D. Dupont, Wei-Qi Wei, Puran Nepal, Adriana M. Hung, Nancy J. Cox, Sara L. Van Driest, QiPing Feng, Jun J. Yang, C. Michael Stein, Jonathan D. Mosley, Cecilia P. Chung
Publikováno v:
Ann Intern Med
BACKGROUND: Thiopurines are an important class of immunosuppressants despite their risk for hematopoietic toxicity and narrow therapeutic indices. Benign neutropenia related to an ACKR1 variant (rs2814778-CC) is common among individuals of African an