Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alyson J. Mangini"'
Autor:
Jean Maguire van Seventer, John A. Meyers, Calvin F. Roff, Alyson J. Mangini, David Sehy, Taro Nagai, Gijs A. van Seventer
Publikováno v:
Cytokine. 35:235-246
Type I interferons (IFN) (IFN-alpha/beta) are recognized as both inhibitors and effectors of autoimmune disease. In multiple sclerosis, IFN-beta therapy appears beneficial, in part, due to its suppression of autoimmune inflammatory Th cell responses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2c8e79cce799e045bcb94be5ae26ea
https://doi.org/10.1016/j.cyto.2006.09.001
https://doi.org/10.1016/j.cyto.2006.09.001
Publikováno v:
Annals of the New York Academy of Sciences. 1108
T helper (Th) cells play a central role in systemic lupus erythematosus (SLE). Activated autoreactive Th cells provide the help required for autoreactive B cells to differentiate and produce pathogenic autoAbs. Both autoAb-containing immune complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1e77b69b47b1f34339b747c45b63ed
https://pubmed.ncbi.nlm.nih.gov/17893966
https://pubmed.ncbi.nlm.nih.gov/17893966
Autor:
Robert Lafyatis, Raphael Lemaire, Jean Maguire van Seventer, Taro Nagai, Michael York, Alyson J. Mangini
Publikováno v:
Arthritis and rheumatism. 56(3)
Objective Microarray analyses of peripheral blood leukocytes have shown that patients with systemic lupus erythematosus express increased levels of type I interferon (IFN)–regulated genes. In this study we examined gene expression by peripheral blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd220ff8d7ee5a11589134df09311196
https://pubmed.ncbi.nlm.nih.gov/17328080
https://pubmed.ncbi.nlm.nih.gov/17328080
Publikováno v:
The Journal of Immunology. 178:LB17-LB18
Type I interferons (IFNs) can have contrasting effects on adaptive Th1 responses. IFN-α/β are well recognized anti-viral agents that promote anti-viral Th1 immune responses. In contrast, IFN-β therapy provides a beneficial effect in multiple scler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f35bb136d7707d18e0009f891442cd
https://doi.org/10.4049/jimmunol.178.supp.b84
https://doi.org/10.4049/jimmunol.178.supp.b84