Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alyson, Marin"'
Autor:
Sally Mullany, David Scott Miller, Katina Robison, Kimberly Levinson, Yi-Chun Lee, S. Diane Yamada, Joan Walker, Maurie Markman, Alyson Marin, Peter Mast, Gere diZerega
Publikováno v:
Gynecologic Oncology Reports, Vol 34, Iss , Pp 100627- (2020)
Submicron particles (~800 nm) of paclitaxel (SPP) contain 1–2 billion molecules of pure drug that release tumoricidal levels of paclitaxel over many weeks. This study compared two dose-levels of SPP instilled into the peritoneal cavity (IP) in 200
Externí odkaz:
https://doaj.org/article/b2b24e54b2824f3f964707993e079cce
Autor:
Max, Kates, Ahmed M, Mansour, Donald L, Lamm, Neal, Shore, Holly, Maulhardt, Alison, Wendt, James, Verco, Alyson, Marin, Karan, Dewnani, Shelagh, Verco, Gere S, diZerega
Publikováno v:
Journal of Urology. 208:821-829
We investigated the safety, preliminary efficacy, and immune effects of large surface area microparticle docetaxel (LSAM-DTX) administered by direct injection after transurethral resection of bladder tumor (TURBT), and by intravesical instillation in
Publikováno v:
Drug Delivery and Translational Research. 13:503-519
This report describes local administration of large surface area microparticle docetaxel (LSAM-DTX: ~ 3.5- to 7.5-µm-sized particles with high relative surface area) in preclinical oncology models and in a clinical trial in urothelial carcinoma. Red
Autor:
Alison Wendt, Sam Campbell, Gere S. diZerega, Marc Iacobucci, Michael Baltezor, Holly Maulhardt, Paul Dorman, Shelagh Verco, Alyson Marin, Emily Williams, James Verco
Publikováno v:
Drug Delivery and Translational Research
This report describes local administration of submicron particle paclitaxel (SPP) (NanoPac®: ~ 800-nm-sized particles with high relative surface area with each particle containing ~ 2 billion molecules of paclitaxel) in preclinical models and clinic
Publikováno v:
Investigational New Drugs
SummaryAdministration of chemotherapeutics as direct injections into tumors offers increased anti-tumor activity and reduced systemic toxicity. In this study, the Renca syngeneic murine xenograft model of renal cancer was used to evaluate the effects
Publikováno v:
Medical Oncology (Northwood, London, England)
We describe here characterization of the response of local and metastatic disease and immunomodulation following intratumoral (IT) injection of submicron particle docetaxel (SPD) administered alone or in combination with systemic antibody anti-mCTLA-
Autor:
Gere S. diZerega, S. Diane Yamada, Katina Robison, Kimberly Levinson, Alyson Marin, Peter Mast, Sally A. Mullany, Maurie Markman, Joan L. Walker, David Miller, Yi-Chun Lee
Publikováno v:
Gynecologic Oncology Reports
Gynecologic Oncology Reports, Vol 34, Iss, Pp 100627-(2020)
Gynecologic Oncology Reports, Vol 34, Iss, Pp 100627-(2020)
Highlights • Patients with ovarian cancer were treated with intraperitoneal submicron particle paclitaxel after debulking surgery. • Following surgery, patients received IV chemotherapy without evidence of enhanced systemic toxicity. • By RECIS
Autor:
David Miller, S.D. Yamada, Peter Mast, Maurie Markman, Sally A. Mullany, Kimberly Levinson, Joan L. Walker, Yi-Chun Lee, Alyson Marin, Katina Robison, Gere S. diZerega
Publikováno v:
Journal of Clinical Oncology. 38:e18046-e18046
e18046 Background: Although advances in chemotherapy, cytoreductive surgery, and maintenance therapy (SOC) improved PFS for high grade epithelial ovarian cancer, > 20% of patients relapse during the first 6 months and 60% relapse after 6 months. Subm