Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Alys R, Clark"'
Autor:
Amy S. Garrett, Mathias W. Roesler, Omkar N. Athavale, Peng Du, Shawn A. Means, Alys R. Clark, Leo K. Cheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The uterus exhibits intermittent electrophysiological activity in vivo. Although most active during labor, the non-pregnant uterus can exhibit activity of comparable magnitude to the early stages of labor. In this study, two types of flexibl
Externí odkaz:
https://doaj.org/article/ae323856ef294491ba8281870723b400
Autor:
Joyce John, Alys R. Clark, Haribalan Kumar, Alain C. Vandal, Kelly S. Burrowes, Margaret L. Wilsher, David G. Milne, Brian Bartholmai, David L. Levin, Ronald Karwoski, Merryn H. Tawhai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Idiopathic pulmonary fibrosis (IPF) is characterised by progressive fibrosing interstitial pneumonia with an associated irreversible decline in lung function and quality of life. IPF prevalence increases with age, appearing most frequently i
Externí odkaz:
https://doaj.org/article/687462c7ceb5446f8e4d513ac3753726
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011359 (2023)
Multi-scale mathematical bioelectrical models of organs such as the uterus, stomach or heart present challenges both for accuracy and computational tractability. These multi-scale models are typically founded on models of biological cells derived fro
Externí odkaz:
https://doaj.org/article/59ba610f72624f21ad6a2da1ce7c5064
Autor:
Stephanie J Woodley, Brittany Moller, Alys R Clark, Melanie D Bussey, Bahram Sangelaji, Meredith Perry, Jennifer Kruger
Publikováno v:
JMIR mHealth and uHealth, Vol 11, p e44929 (2023)
BackgroundWomen with urinary incontinence (UI) may consider using digital technologies (DTs) to guide pelvic floor muscle training (PFMT) to help manage their symptoms. DTs that deliver PFMT programs are readily available, yet uncertainty exists rega
Externí odkaz:
https://doaj.org/article/a3f58cb422944a9f8c88e89ee2c819d2
Autor:
Haribalan Kumar, Robby Green, Daniel M. Cornfeld, Paul Condron, Taylor Emsden, Ayah Elsayed, Debbie Zhao, Kat Gilbert, Martyn P. Nash, Alys R. Clark, Merryn H. Tawhai, Kelly Burrowes, Rinki Murphy, Maryam Tayebi, Josh McGeown, Eryn Kwon, Vickie Shim, Alan Wang, Julie Choisne, Laura Carman, Thor Besier, Geoffrey Handsfield, Thiranja Prasad Babarenda Gamage, Jiantao Shen, Gonzalo Maso Talou, Soroush Safaei, Jerome J. Maller, Davidson Taylor, Leigh Potter, Samantha J. Holdsworth, Graham A. Wilson
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Our study methodology is motivated from three disparate needs: one, imaging studies have existed in silo and study organs but not across organ systems; two, there are gaps in our understanding of paediatric structure and function; three, lack of repr
Externí odkaz:
https://doaj.org/article/0fc92b6f4a7640d8a8cdd81453f039bd
Autor:
Behdad Shaarbaf Ebrahimi, Merryn H. Tawhai, Haribalan Kumar, Kelly S. Burrowes, Eric A. Hoffman, Margaret L. Wilsher, David Milne, Alys R. Clark
Publikováno v:
Pulmonary Circulation, Vol 11, Iss 4, Pp 1-15 (2021)
Pulmonary hypertension has multiple etiologies and so can be difficult to diagnose, prognose, and treat. Diagnosis is typically made via invasive hemodynamic measurements in the main pulmonary artery and is based on observed elevation of mean pulmona
Externí odkaz:
https://doaj.org/article/6779125f93fc4416a1d12fd224f752bb
Autor:
Amy S. Garrett, Shawn A. Means, Mathias W. Roesler, Kiara J. W. Miller, Leo K. Cheng, Alys R. Clark
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The uterus provides protection and nourishment (via its blood supply) to a developing fetus, and contracts to deliver the baby at an appropriate time, thereby having a critical contribution to the life of every human. However, despite this vital role
Externí odkaz:
https://doaj.org/article/d987810e1ec4402ba47bd83d5f7f608b
Autor:
Alys R. Clark, Hanna Fontinha, John Thompson, Sophie Couper, Devanshi Jani, Ali Mirjalili, Laura Bennet, Peter Stone
Publikováno v:
Biology, Vol 12, Iss 9, p 1268 (2023)
The maternal cardiovascular-circulatory system undergoes profound changes almost from the conception of a pregnancy until the postpartum period to support the maternal adaptions required for pregnancy and lactation. Maintenance of cardiovascular home
Externí odkaz:
https://doaj.org/article/2314dc84c6fb4f388dba38f1eb71588f
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Fetal growth restriction (FGR) affects 5–10% of pregnancies, leading to clinically significant fetal morbidity and mortality. FGR placentae frequently exhibit poor vascular branching, but the mechanisms driving this are poorly understood.
Externí odkaz:
https://doaj.org/article/7a25616f991b4c4896ea62f5f50b0dca
Publikováno v:
Annals of Biomedical Engineering. 51:1256-1269
The placenta is a critical fetal exchange organ, with a complex branching tree-like structure. Its surface is covered by a single multinucleated cell, the syncytiotrophoblast, which bathes in maternal blood for most of pregnancy. Mechanosensing prote