Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alycia G. Berman"'
Autor:
Alycia G. Berman, Daniel J. Romary, Katherine E. Kerr, Natalyn E. Gorazd, Morgan M. Wigand, Sourav S. Patnaik, Ender A. Finol, Abigail D. Cox, Craig J. Goergen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Abdominal aortic aneurysm (AAA) formation and expansion is highly complex and multifactorial, and the improvement of animal models is an important step to enhance our understanding of AAA pathophysiology. In this study, we explore our abilit
Externí odkaz:
https://doaj.org/article/58bb105c53454f0aab1b07f8e032f186
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Estrogen agonist raloxifene is an FDA-approved treatment of osteoporosis in postmenopausal women, which may also be a promising prophylactic for painful intervertebral disc (IVD) degeneration. Here, we hypothesized that 1) aging and biological sex co
Externí odkaz:
https://doaj.org/article/7b92e75c276740d1a6247b33a7c45dd5
Autor:
Katherine M. Powell, Alexa P. Brown, Cayla G. Skaggs, Alexis N. Pulliam, Alycia G. Berman, Padmini Deosthale, Lilian I. Plotkin, Matthew R. Allen, David R. Williams, Joseph M. Wallace
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100246- (2020)
Raloxifene (RAL) is an FDA-approved drug used to treat osteoporosis in postmenopausal women. RAL suppresses bone loss primarily through its role as a selective estrogen receptor modulator (SERM). This hormonal estrogen therapy promotes unintended sid
Externí odkaz:
https://doaj.org/article/f1aea291af4247098c0b1433ca290ca9
Publikováno v:
Bone Reports, Vol 10, Iss , Pp - (2019)
Treadmill running and tibial loading are two common modalities used to assess the role of mechanical stimulation on the skeleton preclinically. The primary advantage of treadmill running is its physiological relevance. However, the applied load is co
Externí odkaz:
https://doaj.org/article/436498713e584e7a8564589aac852fe6
Autor:
Benjamin Seelbinder, Eduard Casas, Adrienne K. Scott, Soham Ghosh, Stephanie E. Schneider, Corey P. Neu, Alycia G. Berman, Sarah Calve, Alison R. Swearingen, Kenneth B. Margulies, Craig J. Goergen, Kenneth Bedi, Justin Brumbaugh
Publikováno v:
Nat Biomed Eng
In cardiovascular tissues, changes in the mechanical properties of the extracellular matrix are associated with cellular de-differentiation and with subsequent functional declines. However, the underlying mechanoreceptive mechanisms are largely uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e455ab24d354dfbc5f1e1a76d5f795
https://europepmc.org/articles/PMC9300284/
https://europepmc.org/articles/PMC9300284/
Autor:
Dar Weiss, Bruno V. Rego, Jay D. Humphrey, Alycia G. Berman, Marcos Latorre, Cristina Cavinato, B.J. Tanski, Craig J. Goergen
Publikováno v:
Acta Biomater
[EN] Abdominal aortic aneurysms (AAAs) are characterized histopathologically by compromised elastic fiber integrity, lost smooth muscle cells or their function, and remodeled collagen. We used a recently introduced mouse model of AAAs that combines e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10826468e3be0670da582692252ec27f
https://europepmc.org/articles/PMC8542633/
https://europepmc.org/articles/PMC8542633/
Autor:
O. El Jordi, P. Niziolek, David L. McKinzie, N. Holguin, Alycia G. Berman, N. Bhadouria, Joseph M. Wallace
Estrogen agonist raloxifene is an FDA-approved treatment for osteoporosis in postmenopausal women that may also be a promising prophylactic for painful intervertebral disc (IVD) degeneration. Here, we hypothesized that raloxifene would augment IVD st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb759d66ffbde6049e4db47651974e0
https://doi.org/10.1101/2021.06.29.449482
https://doi.org/10.1101/2021.06.29.449482
Autor:
Alexis N. Pulliam, Matthew R. Allen, Joseph M. Wallace, Katherine M. Powell, Alycia G. Berman, Cayla G. Skaggs
Publikováno v:
Bone
Current interventions to reduce skeletal fragility are insufficient at enhancing both the quantity and quality of bone when attempting to improve overall mechanical integrity. Bisphosphonates, such as Zoledronate (ZOL), are used to treat a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea086840e31a683a25ad14a26cc8253
https://doi.org/10.1016/j.bone.2019.06.018
https://doi.org/10.1016/j.bone.2019.06.018
Autor:
Chi Hwan Lee, Bahar Dhowan, Qi Yang, Craig J. Goergen, Jacqueline C. Linnes, Jongcheon Lim, Hyowon Lee, Alycia G. Berman, Min Ku Kim, Michael D. MacLean
Publikováno v:
J Control Release
With approximately 48,000 attributed deaths in 2017, the opioid overdose is now the leading cause of death amongst Americans under the age of 50. The overdose process can be interrupted by the administration of naloxone, a safe and effective opiate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d43dc115d31d635bf9058bd1d58eb0b
https://doi.org/10.1016/j.jconrel.2019.05.041
https://doi.org/10.1016/j.jconrel.2019.05.041
Autor:
Jennifer Hatch, Joseph M. Wallace, Alexis N. Pulliam, John G Damrath, Madicyn J. Hinton, Alycia G. Berman, Katherine M. Powell
Publikováno v:
Connect Tissue Res
Raloxifene (RAL) is a selective estrogen receptor modulator (SERM) that has previously been shown to cause acellular benefits to bone tissue. Due to these improvements, RAL was combined with targeted tibial loading to assess if RAL treatment during p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3154f6015d177166d2344a388b216f65
https://pubmed.ncbi.nlm.nih.gov/33427519
https://pubmed.ncbi.nlm.nih.gov/33427519