Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alyce J. Mayfosh"'
Autor:
Jascinta P. Santavanond, Yu-Hsin Chiu, Rochelle Tixeira, Zonghan Liu, Jeremy K. Y. Yap, Kaiwen W. Chen, Chen-Lu Li, Yi-Ru Lu, Joan Roncero-Carol, Esteban Hoijman, Stephanie F. Rutter, Bo Shi, Gemma F. Ryan, Amy L. Hodge, Sarah Caruso, Amy A. Baxter, Dilara C. Ozkocak, Chad Johnson, Zoe I. Day, Alyce J. Mayfosh, Mark D. Hulett, Thanh K. Phan, Georgia K. Atkin-Smith, Ivan K. H. Poon
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-12 (2024)
Abstract Discovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological conditions such as cancer and infectious d
Externí odkaz:
https://doaj.org/article/62a57fe64f944d87ab3862e5bd598553
Autor:
Zoe I. Day, Alyce J. Mayfosh, Amy A. Baxter, Scott A. Williams, Joanne M. Hildebrand, Thomas F. Rau, Ivan K. H. Poon, Mark D. Hulett
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 555 (2024)
Here, we describe GS-9, a novel water-soluble fatty acid-based formulation comprising L-lysine and arachidonic acid, that we have shown to induce ferroptosis. GS-9 forms vesicle-like structures in solution and mediates lipid peroxidation, as evidence
Externí odkaz:
https://doaj.org/article/7ae74655cf7a41208939f28a5aa2a6ea
Autor:
Zoe I. Day, Alyce J. Mayfosh, Marie-Claire Giel, Yuning Hong, Scott A. Williams, Jascinta P. Santavanond, Thomas F. Rau, Ivan K. Poon, Mark D. Hulett
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14170 (2022)
Undecylenic acid, a monounsaturated fatty acid, is currently in clinical use as a topical antifungal agent, however the potential for therapeutic application in other disease settings has not been investigated. In this study, we describe a novel plat
Externí odkaz:
https://doaj.org/article/26a3a85fa623410b8aef5f8112eb6a1c
Autor:
Alyce J. Mayfosh, Zoe I. Day, Nathan B. Unsworth, Chun-Qiang Liu, Ruchi Gupta, Soraya Haynes, Rebecca Abraham, Sam Abraham, Zo L. Shaw, Sumeet Walia, Aaron Elbourne, Mark D. Hulett, Thomas F. Rau
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1293 (2022)
The environmental control of microbial pathogens currently relies on compounds that do not exert long-lasting activity on surfaces, are impaired by soil, and contribute to the growing problem of antimicrobial resistance. This study presents the scien
Externí odkaz:
https://doaj.org/article/dd3f8d3a87cf4675902a2eb91ef28c37
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11096 (2021)
The extracellular matrix (ECM) is a structural framework that has many important physiological functions which include maintaining tissue structure and integrity, serving as a barrier to invading pathogens, and acting as a reservoir for bioactive mol
Externí odkaz:
https://doaj.org/article/0f3088540e1a43a9a1a4d96705f9666b
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Heparanase is a β-D-endoglucuronidase that cleaves heparan sulfate, a complex glycosaminoglycan found ubiquitously throughout mammalian cells and tissues. Heparanase has been strongly associated with important pathological processes including inflam
Externí odkaz:
https://doaj.org/article/55d42a36bf414d2ba6d1956f40ea7c55
Publikováno v:
Journal of leukocyte biologyREFERENCES. 111(6)
Heparanase is the only mammalian enzyme capable of cleaving heparan sulfate, a glycosaminoglycan of the extracellular matrix and cell surfaces. Most immune cells express heparanase that contributes to a range of functions including cell migration and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a203fa43d472bece1a3ffe4c85d3a95
https://pubmed.ncbi.nlm.nih.gov/34693552
https://pubmed.ncbi.nlm.nih.gov/34693552
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology, Vol 9 (2019)
Heparanase is a β-D-endoglucuronidase that cleaves heparan sulfate, a complex glycosaminoglycan found ubiquitously throughout mammalian cells and tissues. Heparanase has been strongly associated with important pathological processes including inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43d79510af7ee17c9f31c94309f4743
https://doi.org/10.3389/fonc.2019.00331
https://doi.org/10.3389/fonc.2019.00331
Autor:
Eva M, Putz, Alyce J, Mayfosh, Kevin, Kos, Deborah S, Barkauskas, Kyohei, Nakamura, Liam, Town, Katharine J, Goodall, Dean Y, Yee, Ivan Kh, Poon, Nikola, Baschuk, Fernando, Souza-Fonseca-Guimaraes, Mark D, Hulett, Mark J, Smyth
Publikováno v:
The Journal of clinical investigation. 127(7)
NK cells are highly efficient at preventing cancer metastasis but are infrequently found in the core of primary tumors. Here, have we demonstrated that freshly isolated mouse and human NK cells express low levels of the endo-β-D-glucuronidase hepara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36099f30abcd93eb72be852f75dd6f4a
https://pubmed.ncbi.nlm.nih.gov/28581441
https://pubmed.ncbi.nlm.nih.gov/28581441