Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alyaksandr V Nikitski"'
Publikováno v:
Cancer Medicine, Vol 8, Iss 13, Pp 5831-5839 (2019)
Abstract Background Reactivation of telomerase reverse transcriptase (TERT) is an important event in cancer. Two hotspot mutations in the TERT promoter region, c.‐124C > T (C228T) and c.‐146C > T (C250T), occur in various cancer types including t
Externí odkaz:
https://doaj.org/article/8ed3e7932c334f68987078d64af55197
Autor:
John M. Skaugen, Charit Taneja, Jason B. Liu, Abigail I. Wald, Alyaksandr V. Nikitski, Simion I. Chiosea, Raja R. Seethala, N. Paul Ohori, Esra Karslioglu-French, Sally E. Carty, Marina N. Nikiforova, Linwah Yip, Yuri E. Nikiforov
Publikováno v:
Thyroid. 32:1500-1508
Autor:
Esra Karslioglu French, Alyaksandr V Nikitski, Linwah Yip, Marina N Nikiforova, Yuri E Nikiforov, Sally E Carty
Publikováno v:
Endocrine-Related Cancer. 29:467-473
EIF1AX gene mutations are reported in both benign and malignant thyroid tumors, with unclear outcomes when detected preoperatively. The aim of this study was to determine the features and outcomes of thyroid nodules with various types of mutation ide
Publikováno v:
Thyroid : official journal of the American Thyroid Association.
Radioiodine (RAI) is commonly used for thyroid cancer treatment, although its therapeutic benefits are restricted to iodine-avid tumors. The RAI-refractory disease develops with tumor dedifferentiation involving loss of sodium-iodine symporter (NIS).
Autor:
Marina N. Nikiforova, Abigail I. Wald, Raja R. Seethala, Yuri E. Nikiforov, Linwah Yip, William E. Gooding, Dan P. Zandberg, Sally E. Carty, Alyaksandr V. Nikitski, Robert L. Ferris, Esra Karslioglu-French
Publikováno v:
Cancer
BACKGROUND: Risk stratification for patients with differentiated thyroid cancer (DTC) is based primarily on pathologic tumor characteristics. Accurate preoperative prognostication could allow for more informed initial surgical recommendations, partic
Autor:
Nilma Malik, Yuri E. Nikiforov, Barbara Chadwick, Benjamin L. Witt, Alyaksandr V. Nikitski, Jason P. Hunt, Elie Klam, Devaprabu Abraham
Publikováno v:
Endocrine Practice. 25:1255-1262
Objective: Differentiated thyroid cancer patients uncommonly present with bone metastasis as the initial manifestation. Their molecular profile is largely unknown. The aim of this study was to evaluate the histopathology, molecular profiles, and resp
Autor:
Cihan Kaya, Alyaksandr V. Nikitski, Vincenzo Condello, Marina N. Nikiforova, Abigail I. Wald, Simion I. Chiosea, Yuri E. Nikiforov, Federica Panebianco, Linwah Yip
Publikováno v:
Endocr Relat Cancer
ALK fusions are found in various tumors, including thyroid cancer, and serve as a diagnostic marker and therapeutic target. Spectrum and outcomes of ALK fusions found in thyroid nodules and cancer are not fully characterized. We report a series of 44
Autor:
Alyaksandr V. Nikitski, Susan L. Rominski, Mamta Wankhede, Yuri E. Nikiforov, Daniel L. Altschuler, Federica Panebianco, Cihan Kaya, Hong Yang, Vincenzo Condello
Publikováno v:
Thyroid. 29:1425-1437
Background: Thyroid tumor progression from well-differentiated cancer to poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) involves step-wise dedifferentiation a...
Publikováno v:
Cancer Medicine, Vol 8, Iss 13, Pp 5831-5839 (2019)
Cancer Medicine
Cancer Medicine
Background Reactivation of telomerase reverse transcriptase (TERT) is an important event in cancer. Two hotspot mutations in the TERT promoter region, c.‐124C > T (C228T) and c.‐146C > T (C250T), occur in various cancer types including thyroid ca
Autor:
Cihan Kaya, Lucas Santana-Santos, Sally E. Carty, Abigail I. Wald, Marina N. Nikiforova, Robert L. Ferris, Simion I. Chiosea, Alyaksandr V. Nikitski, Linwah Yip, Adel K. El-Naggar, Vincenzo Condello, Raja R. Seethala, Yuri E. Nikiforov, Somak Roy, Federica Panebianco, Michelle A. Williams
Publikováno v:
Thyroid. 29:161-173
Background: Hyalinizing trabecular tumor (HTT) is a rare thyroid neoplasm with a characteristic trabecular growth pattern and hyalinization. This lesion has been the subject of long-term controversy surrounding its genetic mechanisms, relationship to