Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alya Venyaminova"'
Publikováno v:
Frontiers in Chemistry, Vol 9 (2022)
Hydrogels are biocompatible matrices for local delivery of nucleic acids; however, functional dopants are required to provide efficient delivery into cells. In particular, dendrimers, known as robust nucleic acid carriers, can be used as dopants. Her
Externí odkaz:
https://doaj.org/article/48ff06cc5cb1465d92f1e4dd70dfc33d
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Boron clusters attract considerable attention as promising therapeutic tools for boron neutron capture therapy (BNCT). They combine high boron content with high chemical and biological stability, biorthogonality, and low toxicity. The development of
Externí odkaz:
https://doaj.org/article/7d632a8582f84ffa97e6c36e1a86ffeb
Autor:
Darya Novopashina, Mariya Vorobyeva, Anton Nazarov, Anna Davydova, Nikolay Danilin, Lyudmila Koroleva, Andrey Matveev, Alevtina Bardasheva, Nina Tikunova, Maxim Kupryushkin, Dmitrii Pyshnyi, Sidney Altman, Alya Venyaminova
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Novel alternatives to traditional antibiotics are now of great demand for the successful treatment of microbial infections. Here, we present the engineering and properties of new oligonucleotide inhibitors of RNase P, an essential bacterial enzyme. T
Externí odkaz:
https://doaj.org/article/9d35e16369c444e19be9ff0dbb573aa9
Autor:
Aliaksei Ihnatsyeu-Kachan, Volha Dzmitruk, Evgeny Apartsin, Olga Krasheninina, Maksim Ionov, Svetlana Loznikova, Alya Venyaminova, Katarzyna Miłowska, Dzmitry Shcharbin, Serge Mignani, Maria Angeles Muñoz-Fernández, Jean-Pierre Majoral, Maria Bryszewska
Publikováno v:
Colloids and Interfaces, Vol 1, Iss 1, p 6 (2017)
Currently, RNAi based approaches for cancer treatment involving short double stranded RNA molecules (siRNA) are under vigorous scrutinization. Due to numerous biological obstacles, siRNA delivery into target cells requires protective escort. On the o
Externí odkaz:
https://doaj.org/article/b1954f44f42144faa74b3303ca37affd
Publikováno v:
Molecules, Vol 21, Iss 12, p 1613 (2016)
Nucleic acid aptamers generated through an in vitro selection are currently extensively applied as very valuable biomolecular tools thanks to their prominent advantages. Diversity of spatial structures, ease of production through chemical synthesis a
Externí odkaz:
https://doaj.org/article/a2761d4679d345099e2f36bc2f09acee
Autor:
Ilya, Dovydenko, Mariya, Meschaninova, Anne-Marie, Heckel, Ivan, Tarassov, Alya, Venyaminova, Nina, Entelis
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2277
Defects in human mitochondrial genome can cause a wide range of clinical disorders that still do not have efficient therapies. The natural pathway of small noncoding RNA import can be exploited to address therapeutic RNAs into the mitochondria. To cr
Publikováno v:
Biomaterials. 76
Defects in mitochondrial DNA often cause neuromuscular pathologies, for which no efficient therapy has yet been developed. MtDNA targeting nucleic acids might therefore be promising therapeutic candidates. Nevertheless, mitochondrial gene therapy has
Autor:
Ilya, Dovydenko, Anne-Marie, Heckel, Yann, Tonin, Ali, Gowher, Alya, Venyaminova, Ivan, Tarassov, Nina, Entelis
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1265
Mitochondrial import of small noncoding RNA is found in a large variety of species. In mammalian cells, this pathway can be used for therapeutic purpose, to restore the mitochondrial functions affected by pathogenic mutations. Recently, we developed