Biochemical investigation and in silico analysis of the therapeutic efficacy of Ipriflavone through Tet-1 Surface-Modified-PLGA nanoparticles in Streptozotocin-Induced Alzheimer’s like Disease: Reduced oxidative damage and etiological Descriptors

Autor: Saleh, Samar R., Khamiss, Salma E., Aly Madhy, Somaya, Khattab, Sherine N., Sheta, Eman, Elnozahy, Fatma Y., Thabet, Eman H., Ghareeb, Doaa A., Awad, Doaa, El-bessoumy, Ashraf A.

Publikováno v: In International Journal of Pharmaceutics 25 January 2025 669

Biochemical investigation and in silico analysis of the therapeutic efficacy of Ipriflavone through Tet-1 Surface-Modified-PLGA nanoparticles in Streptozotocin-Induced Alzheimer's like Disease: Reduced oxidative damage and etiological Descriptors.

Autor: Saleh SR; Biochemistry Department, Faculty of Science, Alexandria University, Alexandria 21511, Egypt; Bio-Screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: samar.saleh@alexu.edu.eg., Khamiss SE; Biochemistry Department, Faculty of Science, Alexandria University, Alexandria 21511, Egypt; Bio-Screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: salma.khamiss@alexu.edu.eg., Aly Madhy S; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: Somaya.mady_pg@alexu.edu.eg., Khattab SN; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: sherinekhattab@alexu.edu.eg., Sheta E; Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. Electronic address: iman.sheta@alexmed.edu.eg., Elnozahy FY; Medical Physiology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt. Electronic address: fatma.yousry@alexmed.edu.eg., Thabet EH; Medical Physiology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt; Center of Excellence for Research in Regenerative Medicine and Applications (CERRMA), Faculty of Medicine, Alexandria University, Alexandria, Egypt. Electronic address: e_thabet00@alexmed.edu.eg., Ghareeb DA; Biochemistry Department, Faculty of Science, Alexandria University, Alexandria 21511, Egypt; Bio-Screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: d.ghareeb@alexu.edu.eg., Awad D; Biochemistry Department, Faculty of Science, Alexandria University, Alexandria 21511, Egypt. Electronic address: doaaelsayed363@alexu.edu.eg., El-Bessoumy AA; Biochemistry Department, Faculty of Science, Alexandria University, Alexandria 21511, Egypt. Electronic address: ashraf.elbasomy@alexu.edu.eg.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2024 Dec 02; Vol. 669, pp. 125021. Date of Electronic Publication: 2024 Dec 02.