Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Alwyn Gomez"'
Autor:
Alwyn Gomez, Izabella Marquez, Logan Froese, Tobias Bergmann, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Abrar Islam, Kevin Y. Stein, Frederick A. Zeiler
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Global outcomes have been reported to be associated with cerebrovascular reactivity (CVR) in the acute phase following moderate and severe traumatic brain injury (TBI). The association of CVR in the acute and chronic phase of injury with pat
Externí odkaz:
https://doaj.org/article/49ae0889ba2f46028af1b393507e5ed5
Autor:
Kevin Y. Stein, Fiorella Amenta, Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Younis Ibrahim, Abrar Islam, Tobias Bergmann, Izabella Marquez, Frederick A. Zeiler
Publikováno v:
Neurotrauma Reports, Vol 5, Iss 1, Pp 483-496 (2024)
Cerebrovascular pressure reactivity plays a key role in maintaining constant cerebral blood flow. Unfortunately, this mechanism is often impaired in acute traumatic neural injury states, exposing the already injured brain to further pressure-passive
Externí odkaz:
https://doaj.org/article/de2aee1fe44347b7b8d7445d34ae70b2
Autor:
Amirali Mirsajadi, BSc, Dustin Erickson, BSc, Soumya Alias, MSc, Logan Froese, PhD, Amanjyot Singh Sainbhi, BEng, Alwyn Gomez, MD, Raju Majumdar, BSc, Isuru Herath, BEng, Maggie Wilson, RN, MSc, Ryan Zarychanski, MD, MSc, Frederick A. Zeiler, MD, PhD, Asher A. Mendelson, MD, PhD, on behalf of the Microvasclar Monitoring in Circulatory Shock and Sepsis (MiMICSS) Investigators and the Canadian Critical Care Translational Biology Group, Asher Mendelson, Frederick Zeiler, Ryan Zarychanski, Sylvain Lother, Gloria Vazquez Grande, Olawale Ayilara, J Gordon Boyd, David Maslove, Stephanie Sibley
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1111 (2024)
IMPORTANCE:. Microvascular autoregulation (MA) maintains adequate tissue perfusion over a range of arterial blood pressure (ABP) and is frequently impaired in critical illness. MA has been studied in the brain to derive personalized hemodynamic targe
Externí odkaz:
https://doaj.org/article/990562b7dabf40779c301c365c943be5
Autor:
Kevin Y. Stein, Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Younis Ibrahim, Abrar Islam, Izabella Marquez, Fiorella Amenta, Tobias Bergmann, Frederick A. Zeiler
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Background Optimal cerebral perfusion pressure (CPPopt) has emerged as a promising personalized medicine approach to the management of moderate-to-severe traumatic brain injury (TBI). Though literature demonstrating its association with poor
Externí odkaz:
https://doaj.org/article/eb51e5e27d814d659d27dd2e2a2a3e41
Autor:
Tobias Bergmann, Nuray Vakitbilir, Alwyn Gomez, Abrar Islam, Kevin Y. Stein, Amanjyot Singh Sainbhi, Logan Froese, Frederick A. Zeiler
Publikováno v:
Bioengineering, Vol 11, Iss 9, p 933 (2024)
Artifacts induced during patient monitoring are a main limitation for near-infrared spectroscopy (NIRS) as a non-invasive method of cerebral hemodynamic monitoring. There currently does not exist a robust “gold-standard” method for artifact manag
Externí odkaz:
https://doaj.org/article/0723e176556247eba3b35c8f55a4a7d6
Autor:
Kevin Y. Stein, Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Younis Ibrahim, Frederick A. Zeiler
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 478-494 (2023)
Since its introduction in the 1960s, intracranial pressure (ICP) monitoring has become an indispensable tool in neurocritical care practice and a key component of the management of moderate/severe traumatic brain injury (TBI). The primary utility of
Externí odkaz:
https://doaj.org/article/8489b482fdaa4f349d4a4e9189fcac64
Autor:
Alwyn Gomez, Amanjyot Singh Sainbhi, Kevin Y. Stein, Nuray Vakitbilir, Logan Froese, Frederick A. Zeiler
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Background Cerebrovascular reactivity has been identified as a key contributor to secondary injury following traumatic brain injury (TBI). Prevalent intracranial pressure (ICP) based indices of cerebrovascular reactivity are limited by their
Externí odkaz:
https://doaj.org/article/ddffb4deb24b4021818398595236c824
Autor:
Logan Froese, Amanjyot Singh Sainbhi, Alwyn Gomez, Izzy Marquez, Fiorella Amenta, Carleen Batson, Kevin Y. Stein, Frederick A. Zeiler
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 410-419 (2023)
To optimally assess oscillatory phenomena within physiological variables, spectral domain transforms are used. A discrete Fourier transform (DFT) is one of the most common methods used to attain this spectral change. In traumatic brain injury (TBI),
Externí odkaz:
https://doaj.org/article/bff8d9c1d72d4e629d2ebce81eabdfb6
Autor:
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izzy Marquez, Fiorella Amenta, Kangyun Park, Kevin Y. Stein, Eric P. Thelin, Frederick A. Zeiler
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 307-317 (2023)
Within traumatic brain injury (TBI) care, there is growing interest in pathophysiological markers as surrogates of disease severity, which may be used to improve and individualize care. Of these, assessment of cerebrovascular reactivity (CVR) has bee
Externí odkaz:
https://doaj.org/article/24f573ce1db24fe0837451eb2bcfa24c
Autor:
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izabella Marquez, Fiorella Amenta, Kevin Y. Stein, Frederick A. Zeiler
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Background Although vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the full impact such agents have on cerebrovascular reactivity remains unclear. Using a prospec
Externí odkaz:
https://doaj.org/article/b5b5ee739b064a759da79e6ec448f976