Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alwin A.H.A. Derijck"'
Autor:
R. Jeroen Pasterkamp, Piotr Sirko, Alexi Nott, Justyna Nitarska, Antonella Riccio, Stephan Schacke, Jesse V. Veenvliet, Christian Muchardt, Alwin A.H.A. Derijck, Marten P. Smidt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 110(8), 3113-3118. National Academy of Sciences
Dynamic epigenetic modifications play a key role in mediating the expression of genes required for neuronal development. We previously identified nitric oxide (NO) as a signaling molecule that mediates S-nitrosylation of histone deacetylase 2 (HDAC2)
Autor:
Anne A. Kan, Marina de Wit, Peter C. van Rijen, Eoghan O'Duibhir, Alwin A.H.A. Derijck, R. Jeroen Pasterkamp, Ellen V. S. Hessel, Susan van Erp, Wilco de Jager, Peter H. Gosselaar, Pierre N. E. De Graan
Publikováno v:
Cellular and Molecular Life Sciences; Vol 69
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Mesial temporal lobe epilepsy (mTLE) is a chronic neurological disorder characterized by recurrent seizures. The pathogenic mechanisms underlying mTLE may involve defects in the post-transcriptional regulation of gene expression. MicroRNAs (miRNAs) a
Autor:
Alwin A.H.A. Derijck, Daphne Lelieveld, Youri Adolfs, Giuliano Giuliani, R. Jeroen Pasterkamp, Eoghan O'Duibhir, Marieke G. Verhagen, Toshihide Yamashita, Yuki Fujita, Roel Q.J. Schaapveld, Eljo Y. van Battum, David A. Egan, Vamshidhar R. Vangoor, Thijs de Gunst
Publikováno v:
Journal of Neuroscience, 38(3), 613. Society for Neuroscience
During embryonic development, axons extend over long distances to establish functional connections. In contrast, axon regeneration in the adult mammalian CNS is limited in part by a reduced intrinsic capacity for axon growth. Therefore, insight into
Autor:
Esther B. Baart, Elena Martini, P. de Boer, Alwin A.H.A. Derijck, I. van den Berg, G.W. van der Heijden
Publikováno v:
Molecular Reproduction and Development, 76, 101-8
Molecular Reproduction and Development, 76(1), 101-108. Wiley-Liss Inc.
Molecular Reproduction and Development, 76, 1, pp. 101-8
Molecular Reproduction and Development, 76(1), 101-108. Wiley-Liss Inc.
Molecular Reproduction and Development, 76, 1, pp. 101-8
Contains fulltext : 81811.pdf (Publisher’s version ) (Closed access) In mouse zygotes, many post-translational histone modifications are asymmetrically present in male and female pronuclei. We investigated whether this principle could be used to de
Autor:
Godfried W. van der Heijden, Maud Giele, Peter Boer, Liliana Ramos, Jan A.M. Kremer, Alwin A.H.A. Derijck
Publikováno v:
Human Reproduction, 22, 9, pp. 2368-76
Human Reproduction, 22, 2368-76
Human Reproduction, 22, 2368-76
Contains fulltext : 53507.pdf (Publisher’s version ) (Closed access) BACKGROUND: Among ICSI children de novo structural chromosome aberrations of male descent are increased. Misrepair of double-strand DNA breaks (DSBs) is a prerequisite for such ab
Autor:
Godfried W. van der Heijden, Maud Giele, Casandra C. van Bavel, Marielle E.P. Philippens, Alwin A.H.A. Derijck, Peter Boer
Publikováno v:
DNA Repair, 5, 8, pp. 959-71
DNA Repair, 5, 959-71
DNA Repair, 5, 959-71
Contains fulltext : 49280.pdf (Publisher’s version ) (Closed access) In the mouse, the paternal post-meiotic chromatin is assumed to be devoid of DNA repair after nuclear elongation and protamine-induced compaction. Hence, DNA lesions induced there
Autor:
Karl Mechtler, Alwin A.H.A. Derijck, Antoine H.F.M. Peters, Susanne Opravil, Stefan Kubicek, Makoto Tachibana, Laura Perez-Burgos, Alexander Kohlmaier, Joost H.A. Martens, Roderick J. O'Sullivan, Yoichi Shinkai, Thomas Jenuwein
Publikováno v:
Molecular Cell. 12:1577-1589
Methylation of position-specific lysine residues in histone N termini is a central modification for regulating epigenetic transitions in chromatin. Each methylatable lysine residue can exist in a mono-, di-, or trimethylated state, thereby extending
Autor:
Roberto Ranaldi, Alwin A.H.A. Derijck, Francesca Pacchierotti, P. de Boer, G.W. van der Heijden
Publikováno v:
Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 714, 44-52
Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 714, 1-2, pp. 44-52
Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 714, 1-2, pp. 44-52
Item does not contain fulltext The early pronucleus stage of the mouse zygote has been characterised in vitro as radiosensitive, due to a high rate of induction of chromosome-type chromosome abnormalities (CA). We have investigated the repair of irra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548c4f60ae5f7c80a9bca674ebd91d16
http://hdl.handle.net/2066/97031
http://hdl.handle.net/2066/97031
Autor:
Alwin A.H.A. Derijck, Youri Adolfs, Paolo Giacobini, Filippo Casoni, Andrea Messina, Aldo Fasolo, Gabriella Cagnoni, R.J. Pasterkamp, Nicoletta Ferraris, Susan Wray, Duncan E. Donohue, Phillip R. Kramer
Publikováno v:
Human Molecular Genetics; Vol 20
Reproduction in mammals is dependent on the function of specific neurons that secrete gonadotropin-releasing hormone-1 (GnRH-1). These neurons originate prenatally in the nasal placode and migrate into the forebrain along the olfactory-vomeronasal ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554fa4d86909d674eb8e01f7d8f7817a
http://hdl.handle.net/2318/91593
http://hdl.handle.net/2318/91593
Publikováno v:
Trends in cell biology. 20(9)
To establish axonal connections growth cones must navigate multiple intermediate targets before reaching their final target. During this journey growth cones are guided by extracellular repulsive and attractive signals. Although initially identified