Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alvin S. Kalinda"'
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:28-33
In this practitioner protocol, the radiochemical synthesis of [(11)C] PABA is described in detail, and a quality control summary of three validation productions is presented. The results indicate that the radiotracer product can be produced in good r
Autor:
Hui Wang, James N. Iuliano, Sanjay K. Jain, Alvaro A. Ordonez, Fereidoon Daryaee, Yong Li, Grace E. Yoon, Kayla R. Gogarty, Jonathan Merino, Peter Smith-Jones, Edward A. Weinstein, Zhuo Zhang, Alvin S. Kalinda, Peter J. Tonge, Ronnie C. Mease
Publikováno v:
ACS Infectious Diseases. 4:1635-1644
Staphylococcus aureus is the leading cause of life-threatening infections, frequently originating from unknown or deep-seated foci. Source control and institution of appropriate antibiotics remain challenges, especially with infections due to methici
Autor:
Zhuo, Zhang, Alvaro A, Ordonez, Hui, Wang, Yong, Li, Kayla R, Gogarty, Edward A, Weinstein, Fereidoon, Daryaee, Jonathan, Merino, Grace E, Yoon, Alvin S, Kalinda, Ronnie C, Mease, James N, Iuliano, Peter M, Smith-Jones, Sanjay K, Jain, Peter J, Tonge
Publikováno v:
ACS Infectious Diseases
Staphylococcus aureus is the leading cause of life-threatening infections, frequently originating from unknown or deep-seated foci. Source control and institution of appropriate antibiotics remain challenges, especially with infections due to methici
Publikováno v:
Imaging Infections ISBN: 9783319545905
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f23cf5861470fc062e73618dcece39
https://doi.org/10.1007/978-3-319-54592-9_4
https://doi.org/10.1007/978-3-319-54592-9_4
Autor:
Lauren E. Bambarger, Alvaro A. Ordonez, Mariah H. Klunk, Alvin S. Kalinda, Edward A. Weinstein, Allison M. Murawski, Sanjay K. Jain, Michael E. Urbanowski, Vikram Saini, Supriya Pokkali, Kimberly L. Moulton, Vincent P. DeMarco, Yong S. Chang
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(1)
The modern patient is increasingly susceptible to bacterial infections including those due to multi-drug resistant organisms (MDROs). Noninvasive whole-body analysis with pathogen-specific imaging technologies can significantly improve patient outcom
Autor:
Remo Stohler, Reto Brun, Lindsey Catherine Hess, Sandra Sinishtaj, Alvin S. Kalinda, Aimee R. Usera, Kimberly S. Petersen, John G. D'angelo, Gary H. Posner, Theresa A. Shapiro, Andrew S. Rosenthal, Josefina Santo-Tomas, William A. Maio, Christopher Snyder, Sergio Wittlin, Jacques Chollet, Matthias Rottmann, Lauren E. Woodard, Wonsuk Chang
Publikováno v:
Journal of Medicinal Chemistry. 51:1035-1042
In four or five chemical steps from the 1,2,4-trioxane artemisinin, a new series of 23 trioxane dimers has been prepared. Eleven of these new trioxane dimers cure malaria-infected mice via oral dosing at 3 x 30 mg/kg. The clinically used trioxane dru
Autor:
Alvin S. Kalinda, Courtney C. Aldrich
Publikováno v:
ChemMedChem. 7(4)
Publisher Summary Artemisinin—a 1,2,4-trioxane sesquiterpene lactone with an atypical endoperoxide moiety—is found to be active against the deadly cerebral form of malaria, toxoplasmosis, leishmaniasis, viral infections, certain bacterial infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b153822d3b70a966465a28b40cf4e186
https://doi.org/10.1016/s0065-7743(09)04418-2
https://doi.org/10.1016/s0065-7743(09)04418-2
From 9-substituted DHA, several new artemisinin-derived C-10 acetal ethers and esters were prepared with either a 9-fluoro or a 9-sulfonyl substituent. The very strong inductive electron-withdrawing C-9 substituent is shown to retard considerably C-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd39c6794e9e7a93c72e3176272b322
https://europepmc.org/articles/PMC2668193/
https://europepmc.org/articles/PMC2668193/
Publikováno v:
ChemInform. 37
This paper describes the mon-, di-, and triarylation of the pyrimidine ring. It is possible to introduce one or more aryl rings in generally good yields and in a specific order, namely first in position 4, second in position 6, followed by position 2