Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alvin R Acebedo"'
Autor:
Mellissa C. Alcantara, Kentaro Suzuki, Alvin R. Acebedo, Daiki Kajioka, Satoshi Hirohata, Tsuneyasu Kaisho, Yu Hatano, Kazuo Yamagata, Satoru Takahashi, Gen Yamada
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105609- (2022)
Summary: While androgen is considered a pivotal regulator of sexually dimorphic development, it remains unclear how it orchestrates the differentiation of reproductive organs. Using external genitalia development as a model, we showed that androgen,
Externí odkaz:
https://doaj.org/article/2e53d6a84d7943b6ad8d066ec65b167e
Autor:
Alvin R Acebedo, Mellissa C Alcantara, Tsuyoshi Nakanishi, Takehiko Ogawa, Gen Yamada, Kentaro Suzuki
Publikováno v:
Toxicological Sciences. 190:13-22
Many industrial chemicals have been reported as antiandrogenic substances. Exposure to these substances represents a potential risk to human health, particularly to the development of reproductive organs such as embryonic external genitalia (eExG). C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842cc0cd720969aa963fba47e25a316c
https://doi.org/10.1093/toxsci/kfac085
https://doi.org/10.1093/toxsci/kfac085
Autor:
Yasuhiro Minami, Yuki Sakamoto, Mellissa C. Alcantara, Gen Yamada, Michiru Nishita, Akira Kikuchi, Kentaro Suzuki, Alvin R. Acebedo
Publikováno v:
Congenital Anomalies. 61:212-219
External genitalia development in mice involves multiple developmental processes under the regulation of various signaling pathways. Wnt5a, one of the major Wnt ligands, is a crucial developmental regulator of outgrowing organs such as the limb, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8e352f0ba2a9d17e8b2dd94a8dc962
https://doi.org/10.1111/cga.12438
https://doi.org/10.1111/cga.12438
Autor:
Mellissa C, Alcantara, Kentaro, Suzuki, Alvin R, Acebedo, Daiki, Kajioka, Satoshi, Hirohata, Tsuneyasu, Kaisho, Yu, Hatano, Kazuo, Yamagata, Satoru, Takahashi, Gen, Yamada
Publikováno v:
iScience. 25(12)
While androgen is considered a pivotal regulator of sexually dimorphic development, it remains unclear how it orchestrates the differentiation of reproductive organs. Using external genitalia development as a model, we showed that androgen, through t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22d10995fb9de6ab4c6d96e7676df998
https://pubmed.ncbi.nlm.nih.gov/36465133
https://pubmed.ncbi.nlm.nih.gov/36465133
Autor:
Gen Yamada, Kentaro Suzuki, Alvin R. Acebedo, Mizuki Kajimoto, Taiju Hyuga, Yoshichika Yoshioka, Daiki Hashimoto, Shinichi Miyagawa, Jun ichiro Enmi
Publikováno v:
Differentiation. 110:29-35
Development of external genitalia (ExG) has been a topic of long mystery in the field of organogenesis research. Early stage male and female of mouse embryos develop a common genital tubercle (GT) in the perineum whose outgrowth extends distally from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b738fe8b56a384a769f83da3ec7de3
https://doi.org/10.1016/j.diff.2019.08.004
https://doi.org/10.1016/j.diff.2019.08.004
Autor:
Yukiko Ogino, Ryuma Haraguchi, Daiki Kajioka, Shoko Matsushita, Aki Murashima, Shinichi Miyagawa, Gen Yamada, Kentaro Suzuki, Alvin R. Acebedo
Publikováno v:
Nature Reviews Urology. 15:358-368
The biology of masculinization is fundamentally important for understanding the embryonic developmental processes that are involved in the development of the male reproductive tract, external genitalia, and also the tumorigenesis of prostate cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab3bb54e623cb150ccc9e5f76425366
https://doi.org/10.1038/s41585-018-0008-y
https://doi.org/10.1038/s41585-018-0008-y
Autor:
Kentaro Suzuki, Alvin R. Acebedo, Yuki Sato, Hisashi Haga, Gen Yamada, Robert S. Adelstein, Ken ichi Matsumoto, Naomi Nakagata, Mitsuyoshi Nakao, Toru Takeo, Shinichi Miyagawa, Shinjiro Hino, Mellissa C. Alcantara, Kenji Shimamura, Ryuichi Nishinakamura
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Communications Biology
Communications Biology
The morphogenesis of mammalian embryonic external genitalia (eExG) shows dynamic differences between males and females. In genotypic males, eExG are masculinized in response to androgen signaling. Disruption of this process can give rise to multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69eae433c147353742b2bc37af7f0293
https://doi.org/10.1038/s42003-019-0336-3
https://doi.org/10.1038/s42003-019-0336-3
Autor:
Kentaro Suzuki, Alvin R. Acebedo, Gen Yamada, Daiki Hashimoto, Taiju Hyuga, Mellissa C. Alcantara
Publikováno v:
Congenital anomalies. 59(3)
Development of external genitalia and perineum is the subject of developmental biology as well as toxicology and teratology researches. Cloaca forms in the lower (caudal) end of endoderm. Such endodermal epithelia and surrounding mesenchyme interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bacab8d8f84d74bdcaa02cdf412d24
https://pubmed.ncbi.nlm.nih.gov/30554442
https://pubmed.ncbi.nlm.nih.gov/30554442