Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alvin P. Makohon-Moore"'
Autor:
Jinlong Huang, Yi Zhong, Alvin P. Makohon-Moore, Travis White, Maria Jasin, Mark A. Norell, Ward C. Wheeler, Christine A. Iacobuzio-Donahue
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110771- (2022)
Summary: We performed a comparative analysis of human and 12 non-human primates to identify sequence variations in known cancer genes. We identified 395 human-specific fixed non-silent substitutions that emerged during evolution of human. Using bioin
Externí odkaz:
https://doaj.org/article/ea9a3d028d344fb7a83f8ff806b9eb82
Autor:
Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Ivana Bozic, Krishnendu Chatterjee, Christine A. Iacobuzio-Donahue, Bert Vogelstein, Martin A. Nowak
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Tumours frequently metastasize to multiple anatomical sites and understanding how these different metastases evolve may be important for therapy. Here, the authors develop a method—Treeomics—that can construct phylogenies from multiple metastases
Externí odkaz:
https://doaj.org/article/094af776195f4129b91a819f0e100749
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Figures S1-S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20b9f9455c55ab9c9d3787b7aadb2c5
https://doi.org/10.1158/2159-8290.22535195.v1
https://doi.org/10.1158/2159-8290.22535195.v1
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Supplemental Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199151f3e69542070ed2df494bce9bbb
https://doi.org/10.1158/2159-8290.22535192.v1
https://doi.org/10.1158/2159-8290.22535192.v1
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Figure S6 shows phylogenies based on point mutations with UV signature mutations removed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f164bba3f3f32ada1a3f4bfbb99cc4
https://doi.org/10.1158/1078-0432.22479737
https://doi.org/10.1158/1078-0432.22479737
Tables S1-S8 from The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Supplementary Tables S1-S8 show the samples used for study (Table S1), the somatic single nucleotide variants, small insertions and small deletions (Table S2), the somatic copy number alterations anallyzed (Table S3), the gene list used to analyze so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b4139b47cb30c51b6cd5befd1a5b0
https://doi.org/10.1158/1078-0432.22479734.v1
https://doi.org/10.1158/1078-0432.22479734.v1
Autor:
Christine A. Iacobuzio-Donahue, Suzanne L. Topalian, Barry S. Taylor, Timothy A. Chan, David B. Solit, Nicholas D. Socci, Rachel Karchin, Paul B. Chapman, Michael A. Postow, Nadeem Riaz, Vladimir Makarov, Zachary Kohutek, Rajya Kappagantula, Priscilla Baez, Collin Tokheim, Akimasa Hayashi, Craig M. Bielski, Jungeui Hong, Amanda Zucker, Jody E. Hooper, Evan J. Lipson, Alvin P. Makohon-Moore
Purpose:Melanoma is a biologically heterogeneous disease composed of distinct clinicopathologic subtypes that frequently resist treatment. To explore the evolution of treatment resistance and metastasis, we used a combination of temporal and multiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6224543d5704e454172689636f33e8cd
https://doi.org/10.1158/1078-0432.c.6530294
https://doi.org/10.1158/1078-0432.c.6530294
Publikováno v:
JCO Precision Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a07b4ab798058017ad40d1941f75d04c
https://doi.org/10.1200/po.22.00698
https://doi.org/10.1200/po.22.00698
Autor:
Alvin P. Makohon-Moore
Publikováno v:
Cancer Research. 83:NG08-NG08
Cancer is an evolutionary disease driven by molecular alterations in cancer cells and concomitant tumor microenvironments. Unfortunately, cancer cells often evolve into aggressive tumors that ultimately evade treatment. Thus, in order to improve clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3156270f775305b341b6e6d0ca1fc70
https://doi.org/10.1158/1538-7445.am2023-ng08
https://doi.org/10.1158/1538-7445.am2023-ng08
Autor:
Rajya L. Kappagantula, Alvin P. Makohon-Moore, Shigeaki Umeda, Elias-Ramzey R. Karnoub, Jerry P. Melchor, Laura D. Wood, Christine A. Iacobuzio-Donahue
Publikováno v:
Cancer Research. 83:2148-2148
Introduction: Regardless of the stage at diagnosis most patients with pancreatic ductal adenocarcinoma develop peritoneal disease and some malignant ascites (MA) as well. Prior studies have shown that MA negatively affects overall treatment efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6d710a095f216e767982a5cfde9e7a8
https://doi.org/10.1158/1538-7445.am2023-2148
https://doi.org/10.1158/1538-7445.am2023-2148