Enhancing myocardial repair with CardioClusters

Autor: Megan M. Monsanto, Bingyan J. Wang, Zach R. Ehrenberg, Oscar Echeagaray, Kevin S. White, Roberto Alvarez, Kristina Fisher, Sharon Sengphanith, Alvin Muliono, Natalie A. Gude, Mark A. Sussman

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)

Despite recent progress to advance cardiac cell-based therapy for patients, heart failure mortality rivals most cancers. Here, the authors describe an approach to control and pattern 3 distinct human cardiac cell populations to promote superior repai

Externí odkaz: https://doaj.org/article/d8965aba695e4b73854957d83edbac8e

Adaptation within embryonic and neonatal heart environment reveals alternative fates for adult c‐kit+ cardiac interstitial cells

Autor: Sharon Sengphanith, Megan M. Monsanto, Roberto Sacripanti, Roberto Alvarez, Alvin Muliono, Mark A. Sussman, Joi Weeks, Bingyan J. Wang

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 5, Pp 620-635 (2020)
Stem cells translational medicine, vol 9, iss 5

Cardiac interstitial cells (CICs) perform essential roles in myocardial biology through preservation of homeostasis as well as response to injury or stress. Studies of murine CIC biology reveal remarkable plasticity in terms of transcriptional reprog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67671b5f8d2f5fd2d89aad701b9fb618
http://europepmc.org/articles/PMC7180292

Abstract 36: Cardiac Progenitor Cell Lineage Tracing During Embryonic Cardiomyogenesis

Autor: Bingyan J Wang, Alvin Muliono, Roberto Alvarez, Mark A Sussman

Publikováno v: Circulation Research. 121

Introduction: Stem cell therapy represents great promises to myocardium regeneration. Multipotent c-Kit pos cardiac progenitor cells (CPCs) are able to differentiate into endothelial cells, smooth muscle cells, and cardiomyocytes. However, fundamenta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dbafec9b47d3e258083e1fff3e8de6e
https://doi.org/10.1161/res.121.suppl_1.36

Cardiac Progenitor Cell Lineage Tracing During Embryonic Cardiomyogenesis

Autor: Mark A. Sussman, Roberto Alvarez, Bingyan J. Wang, Alvin Muliono

Publikováno v: Journal of Molecular and Cellular Cardiology. 112:138

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8549bd915ce7cb91ed452815600dd144
https://doi.org/10.1016/j.yjmcc.2017.07.027