Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alvin Lyckman"'
Publikováno v:
Journal of Neurochemistry. 119:377-388
Amyloid precursor protein (APP) family members and their proteolytic products are implicated in normal nervous system function and Alzheimer's disease pathogenesis. APP processing and Aβ secretion are regulated by neuronal activity. Various data sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::098c0c1e700b0531be6865b00f820420
https://doi.org/10.1111/j.1471-4159.2011.07419.x
https://doi.org/10.1111/j.1471-4159.2011.07419.x
Autor:
Henry W. Querfurth, Salvatore Oddo, Alvin Lyckman, Frank M. LaFerla, Alexander Shtifman, Jose R. Lopez
Publikováno v:
Journal of Neurochemistry. 105:262-271
Neurodegeneration in Alzheimer's disease (AD) has been linked to intracellular accumulation of misfolded proteins and dysregulation of intracellular Ca2+. In the current work, we determined the contribution of specific Ca2+ pathways to an alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f37d67a5332ca63050420c1b5148b2
https://doi.org/10.1111/j.1471-4159.2007.05135.x
https://doi.org/10.1111/j.1471-4159.2007.05135.x
Autor:
Daniela Tropea, Mriganka Sur, Akiya Watakabe, Catherine A. Leamey, Tetsuo Yamamori, Cortina L. McCurry, Alvin Lyckman, Sam Horng, Audra Van Wart
The mapping of eye-specific, geniculocortical inputs to primary visual cortex (V1) is highly sensitive to the balance of correlated activity between the two eyes during a restricted postnatal critical period for ocular dominance plasticity. This crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5c206d68dd698e2a684d13c72e080e
https://hdl.handle.net/10919/83396
https://hdl.handle.net/10919/83396
Autor:
Alvin Lyckman
Publikováno v:
Alzheimer's & Dementia. 3
Methods: Abnormally hyperphosphorylated tau was isolated from AD brain cytosol (AD P-tau), and its ability to inhibit microtubule assembly and self-assembly into filaments was studied before and after dephosphorylation with protein phosphatase-2A (PP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94243bc94da7da1a90786e0ff6dfbb50
https://doi.org/10.1016/j.jalz.2007.04.050
https://doi.org/10.1016/j.jalz.2007.04.050
Autor:
Sam Horng, Hongbo Yu, Sayan Mukherjee, Gabriel Kreiman, Alvin Lyckman, Mriganka Sur, Daniela Tropea
Publikováno v:
Nature neuroscience. 9(5)
Two key models for examining activity-dependent development of primary visual cortex (V1) involve either reduction of activity in both eyes via dark-rearing (DR) or imbalance of activity between the two eyes via monocular deprivation (MD). Combining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5feff7b0b98c0d9a422254a04e63b0b2
https://pubmed.ncbi.nlm.nih.gov/16633343
https://pubmed.ncbi.nlm.nih.gov/16633343
Publikováno v:
Visual neuroscience. 22(1)
Brain-derived neurotrophic factor (BDNF) is a preferred ligand for a member of the tropomyosin-related receptor family, trkB. Activation of trkB is implicated in various activity-independent as well as activity-dependent growth processes in many deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10237ad409c276505b2ee1b4a308821c
https://pubmed.ncbi.nlm.nih.gov/15842738
https://pubmed.ncbi.nlm.nih.gov/15842738