Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alvin Ho Kwan Cheung"'
Autor:
Alvin Ho-Kwan Cheung, Kit-Yee Wong, Xiaoli Liu, Fenfen Ji, Chris Ho-Lam Hui, Yihan Zhang, Johnny Sheung-Him Kwan, Bonan Chen, Yujuan Dong, Raymond Wai-Ming Lung, Jun Yu, Kwok Wai Lo, Chi Chun Wong, Wei Kang, Ka-Fai To
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-14 (2023)
Abstract MLK4, a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family, has been implicated in cancer progression. However, its role in lung adenocarcinoma has not been characterized. Here, we showed that MLK4 was overexpressed
Externí odkaz:
https://doaj.org/article/1fab759148bb485a803a9fe5b39656cf
Autor:
Chi Chun Wong, Jian-Lin Wu, Fenfen Ji, Wei Kang, Xiqing Bian, Huarong Chen, Lam-Shing Chan, Simson Tsz Yat Luk, Samuel Tong, Jiaying Xu, Qiming Zhou, Dabin Liu, Hao Su, Hongyan Gou, Alvin Ho-Kwan Cheung, Ka Fai To, Zongwei Cai, Jerry W. Shay, Jun Yu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Looking for metabolic-associated vulnerabilities is a promising approach for therapeutic intervention in KRAS-mutant colorectal cancer. Here, the authors show that the cholesterol-uptake regulator PCSK9 drives tumourigenesis and is a therapeutic targ
Externí odkaz:
https://doaj.org/article/b983ec1445e54ade901f9b1e5f30d6ee
Autor:
Alvin Ho‐Kwan Cheung, Chris Ho‐Lam Hui, Kit Yee Wong, Xiaoli Liu, Bonan Chen, Wei Kang, Ka Fai To
Publikováno v:
International Journal of Cancer. 152:1510-1525
The use of cell cycle inhibitors has necessitated a better understanding of the cell cycle in tumor biology to optimize the therapeutic approach. Cell cycle aberrations are common in cancers, and it is increasingly acknowledged that these aberrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54fbc75a43ef049436b4b3f1b01cd9c
https://doi.org/10.1002/ijc.34288
https://doi.org/10.1002/ijc.34288
Autor:
Chun Wai Mui, Wai Nok Chan, Bonan Chen, Alvin Ho‐Kwan Cheung, Jun Yu, Kwok Wai Lo, Huixing Ke, Wei Kang, Ka Fai To
Publikováno v:
International Journal of Cancer. 152:558-571
Accumulating evidence has underscored the importance of the Hippo-YAP1 signaling in lung tissue homeostasis, whereas its deregulation induces tumorigenesis. YAP1 and its paralog TAZ are the key downstream effectors tightly controlled by the Hippo pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548282b98bcb6fc45a7f755f5158b4ff
https://doi.org/10.1002/ijc.34249
https://doi.org/10.1002/ijc.34249
Autor:
Kit Yee Wong, Alvin Ho‐Kwan Cheung, Bonan Chen, Wai Nok Chan, Jun Yu, Kwok Wai Lo, Wei Kang, Ka Fai To
Publikováno v:
International Journal of Cancer. 151:1195-1215
Lung cancer is the common and leading cause of cancer death worldwide. The tumor microenvironment has been recognized to be instrumental in tumorigenesis. To have a deep understanding of the molecular mechanism of nonsmall cell lung carcinoma (NSCLC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102c585ba2ef0f0d93d47c2b604799b5
https://doi.org/10.1002/ijc.34127
https://doi.org/10.1002/ijc.34127
Autor:
Alvin Ho-Kwan Cheung, Kit-Yee Wong, Cho-Han Chiang, Xiaoli Liu, Yihan Zhang, Chris Ho-Lam Hui, Bonan Chen, Yifei Wang, Chit Chow, Wei Kang, Ka-Fai To
Publikováno v:
American journal of clinical pathology.
Objectives Comprehensive data synthesis of the clinical parameters that affect plasma EGFR mutation test results in non–small cell lung carcinoma is lacking. Although individual studies have suggested a variety of patient characteristics that can a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6334f77fb5361fa2257f65edb025745d
https://pubmed.ncbi.nlm.nih.gov/36573768
https://pubmed.ncbi.nlm.nih.gov/36573768
Autor:
Liuyang Zhao, Xiang Zhang, Yunfei Zhou, Kaili Fu, Harry Cheuk-Hay Lau, Tommy Wai-Yiu Chun, Alvin Ho-Kwan Cheung, Olabisi Oluwabukola Coker, Hong Wei, William Ka-Kei Wu, Sunny Hei Wong, Joseph Jao-Yiu Sung, Ka Fai To, Jun Yu
Publikováno v:
Oncogene. 41(36)
Large-scale fecal shotgun metagenomic sequencing revealed the high abundance of Parvimonas micra in colorectal cancer (CRC) patients. We investigated the role and clinical significance of P. micra in colorectal tumorigenesis. The abundance of P. micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8ca74575bb82da3b606174652339a6
https://pubmed.ncbi.nlm.nih.gov/35882981
https://pubmed.ncbi.nlm.nih.gov/35882981
Autor:
Gilberto K.K. Leung, Alvin Ho Kwan Cheung, Cesar Wong, William C. Cho, Hin-Fung Andy Tsang, Nancy B.Y. Tsui, Xiao Meng Pei, Yin Kwan Evelyn Wong
Publikováno v:
OBM Genetics. 4:1-11
Background: Vestibular schwannoma is an intracranial tumor which can lead to devastating neurological deficit and is prone to recurrence after surgery. Patients with inherited neurofibromatosis type 2 (NF2) syndrome are particularly susceptible to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89574b606abd8ea20c413682e0276a8f
https://doi.org/10.21926/obm.genet.2002112
https://doi.org/10.21926/obm.genet.2002112
Autor:
Wai Nok Chan, Yujuan Dong, Alvin Ho-Kwan Cheung, Alfred S. L. Cheng, Kam Tong Leung, Wei Kang, William K.K. Wu, Huixing Ke, Xiaoli Liu, Chun Wai Mui, Ka Fai To, Kwok Wai Lo, Bonan Chen, Zhaocai Zhou, Yifei Wang, Yi Pan, Jun Yu, Jinglin Zhang, Chi Chun Wong, Ronald C. K. Chan, Li Liang, Aden K. Y. Chan
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 20, Iss 1, Pp 1-8 (2021)
Molecular Cancer, Vol 20, Iss 1, Pp 1-8 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d29f1c9b244b88c079c3260b9c19007
https://pubmed.ncbi.nlm.nih.gov/34772410
https://pubmed.ncbi.nlm.nih.gov/34772410
Autor:
Lui Ng, Timothy Ming-Hun Wan, Colin Siu-Chi Lam, Ariel Ka-Man Chow, Sunny Kit-Man Wong, Johnny Hon-Wai Man, Hung-Sing Li, Nathan Shiu-Man Cheng, Ryan Chung-Hei Pak, Alvin Ho-Kwan Cheung, Thomas Chung-Cheung Yau, Oswens Siu-Hung Lo, Dominic Chi-Chung Foo, Jensen Tung-Chung Poon, Ronnie Tung-Ping Poon, Roberta Wen-Chi Pang, Wai-Lun Law
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126219 (2015)
The overall prognosis of colorectal cancer (CRC) patients is unsatisfactory due to cancer metastasis after operation. This study aims to investigate the clinical significance of plasma osteopontin (OPN) levels as minimally invasive, predictive, and s
Externí odkaz:
https://doaj.org/article/d785229062a24d038bcc332f593a3d78