Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alvin H. Bachman"'
Autor:
Alvin H. Bachman, Babak A. Ardekani
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 3, Iss , Pp 100028- (2020)
Change point analysis can reveal when a biomarker starts to diverge from the pattern of normal aging. This paper analyzes several biomarkers from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to estimate the sequence and timing of their ch
Externí odkaz:
https://doaj.org/article/de3b023537ea44838f0567f908a88cf0
Publikováno v:
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: Asymmetric atrophy of the hippocampus is an important clinical finding in normal aging and Alzheimer disease. In this study, we investigate the associations between the magnitude and asymmetry of hippocampal volumetric integri
Publikováno v:
Psychiatry research. Neuroimaging. 301
Early detection of Alzheimer’s disease (AD) is important for timely interventions and developing new treatments. Hippocampus atrophy is an early biomarker of AD. The hippocampal parenchymal fraction (HPF) is a promising measure of hippocampal struc
Autor:
Ali Asaei, Alzheimer's Disease Neuroimaging Initiative, Alvin H. Bachman, Asim M. Mubeen, Babak A. Ardekani, John J. Sidtis
Publikováno v:
Journal of Neuroradiology. 44:381-387
Rationale and objectives Early prediction of incipient Alzheimer's disease (AD) dementia in individuals with mild cognitive impairment (MCI) is important for timely therapeutic intervention and identifying participants for clinical trials at greater
Autor:
Alvin H. Bachman, Christopher K. Cain, Robert M. Sears, Morris H. Baslow, David N. Guilfoyle, Donald A. Wilson, Scott Gerum
Publikováno v:
NMR in Biomedicine. 29:1678-1687
Brain activation studies in humans have shown the dynamic nature of neuronal N-acetylaspartate (NAA) and N-acetylaspartylglutamate (NAAG) based on changes in their MRS signals in response to stimulation. These studies demonstrated that upon visual st
Publikováno v:
Journal of Alzheimer's Disease. 50:847-857
BACKGROUND Hippocampus (HC) atrophy is a hallmark of early Alzheimer's disease (AD). Atrophy rates can be measured by high-resolution structural MRI. Longitudinal studies have previously shown sex differences in the progression of functional and cogn
Publikováno v:
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
IntroductionWe investigate whether longitudinal callosal atrophy could predict conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD).MethodsLongitudinal (baseline + 1-year follow-up) MRI scans of 132 MCI subjects from the Alzhei
Publikováno v:
Journal of Neuroscience Methods. 221:78-84
We propose a fused lasso logistic regression to analyze callosal thickness profiles. The fused lasso regression imposes penalties on both the l1-norm of the model coefficients and their successive differences, and finds only a small number of non-zer
Publikováno v:
Journal of Alzheimer's disease : JAD. 55(1)
Background Mild cognitive impairment (MCI) is a transitional stage from normal aging to Alzheimer's disease (AD) dementia. It is extremely important to develop criteria that can be used to separate the MCI subjects at imminent risk of conversion to A
Autor:
Alvin H. Bachman, Babak A. Ardekani
Publikováno v:
Alzheimer's & Dementia. 12