Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alvin G. Denenberg"'
Autor:
James S. Titus, Alvin G. Denenberg, Gillian A. Geffin, Nabil A. Munfakh, David C. Hoaglin, Neil E. Doherty, John B. Steinberg, Willard M. Daggett
Publikováno v:
The Annals of Thoracic Surgery. 51:620-629
Reports differ as to the efficacy of glucose and insulin as cardioplegic additives. Although deliberate oxygenation of crystalloid cardioplegic solutions improves myocardial protection, little is known about the protection afforded by glucose and ins
Autor:
Philip C, Chen, Derek S, Wheeler, Vivek, Malhotra, Kelli, Odoms, Alvin G, Denenberg, Hector R, Wong
Publikováno v:
Inflammation
Interleukin-8 (IL-8) is a principle neutrophil chemoattractant and activator in humans. There is interest in developing novel pharmacological inhibitors of IL-8 gene expression as a means for modulating inflammation in disease states such as acute lu
Autor:
Bruce J, Grossman, Thomas P, Shanley, Kelli, Odoms, Katherine E, Dunsmore, Alvin G, Denenberg, Hector R, Wong
Publikováno v:
Inflammation. 26(3)
Previous studies demonstrated important interactions between the heat shock response and the IkappaBalpha/NF-kappaB pathway when these two pathways are induced sequentially. One such interaction involves the ability of heat shock to inhibit subsequen
Publikováno v:
Shock (Augusta, Ga.). 17(4)
Hyperoxia and tumor necrosis factor-alpha (TNFalpha) are two canonical signals centrally involved in the pathophysiology of acute lung injury. We have attempted to elucidate the effects of these two stimuli on the signal transduction pathways of lung
Autor:
David F. Torchiana, James S. Titus, Chiwon Hahn, Joseph A. Lahorra, Gillian A. Geffin, Alvin G. Denenberg, Willard M. Daggett, C A Bashour
Publikováno v:
The Journal of surgical research. 88(2)
Background.Enhanced recovery after cardioplegic arrest has been observed in rat hearts with hypertrophy induced by hemodynamic overload. We hypothesize that this is related to altered characteristics of hypertrophied myocardium—reflected by increas
Autor:
Gillian A. Geffin, Robert S McDonald, David F. Torchiana, Seth D Blank, Willard M. Daggett, Joseph A. Lahorra, James S. Titus, Alvin G. Denenberg
Publikováno v:
The Annals of thoracic surgery. 65(2)
Background . Although cardioplegic protection of the hypertrophied heart remains a clinical challenge, we have previously observed enhanced recovery in rat hearts with pressure-overload hypertrophy induced by aortic banding. We investigated whether t
Autor:
Willard M. Daggett, John B. Steinberg, Dennis D. O'Keefe, Alvin G. Denenberg, Nabil A. Munfakh, Gillian A. Geffin, James S. Titus
Publikováno v:
The Journal of surgical research. 51(6)
Patients with left ventricular hypertrophy (LVH) have a worse outcome after cardiac surgery than those without hypertrophy. We studied protection of hearts with LVH in an isolated rat heart model using multidose, cold, oxygenated cardioplegia. LVH wa
Autor:
Gillian A. Geffin, Dennis D. O'Keefe, Willard M. Daggett, William G. Hendren, Tim R. Love, Alvin G. Denenberg
Publikováno v:
The Annals of Thoracic Surgery. 58:1558-1559
The content of dissolved O 2 (the major source of O 2 far the myocardium) of dilute blood cardioplegic solution (dBCS) varied widely when oxygenated at 4 °C by surface flow of O 2 in a Bentley BCR-3500 cardiotomy reservoir. We have modified the syst
Autor:
Lauren Sanlorenzo, Bin Zhao, Donn Spight, Alvin G Denenberg, Kristen Page, Hector R Wong, Thomas P Shanley
Publikováno v:
Critical Care Medicine; Nov2004, Vol. 32 Issue 11, p2284-2292, 9p
Publikováno v:
The American journal of physiology. 252(4 Pt 2)
Regional myocardial blood flow measurements in the right heart bypass preparation can be particularly valuable, since this preparation provides control of the main hemodynamic determinants of coronary blood flow. We examined the validity of aortic re