Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alvin C. K. Teo"'
Autor:
Alvin C. K. Teo, David I. Roper
Publikováno v:
Antibiotics, Vol 4, Iss 4, Pp 495-520 (2015)
We are entering an era where the efficacy of current antibiotics is declining, due to the development and widespread dispersion of antibiotic resistance mechanisms. These factors highlight the need for novel antimicrobial discovery. A large number of
Externí odkaz:
https://doaj.org/article/e026b66c4981431391b230448c5c7109
Autor:
Riyaz Maderbocus, Vassiliy N. Bavro, Gabriela Boelter, Ian R. Henderson, Douglas G. Ward, Manuel Banzhaf, Timothy J. Knowles, Eva Heinz, Mark Jeeves, Alvin C. K. Teo, Amanda E. Rossiter, David I. Roper, Timothy J. Wells, Adam Colyer, Dema Alodaini, Peter J. Wotherspoon, Yanina R. Sevastsyanovich, Adam F. Cunningham, Faye C. Morris, Shu-Sin Chng, Jack A. Bryant, Douglas F. Browning, Michael Overduin, Pooja Sridhar, Kara A. Staunton, Christopher Icke, Trevor Lithgow, Emily C. A. Goodall, Zhi-Soon Chong
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The Gram-negative outer-membrane envelops the bacterium and functions as a permeability barrier against antibiotics, detergents, and environmental stresses. Some virulence factors serve to maintain the integrity of the outer membrane, including DolP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73781758231d185cf3af7872510f68f
http://wrap.warwick.ac.uk/147267/1/WRAP-structure-dual-BON-domain-protein-DolP-identifies-phospholipid-binding-new-mechanism-protein-localisation-Roper-2020.pdf
http://wrap.warwick.ac.uk/147267/1/WRAP-structure-dual-BON-domain-protein-DolP-identifies-phospholipid-binding-new-mechanism-protein-localisation-Roper-2020.pdf
Autor:
Adam Colyer, Riyaz Maderbocus, Peter J. Wotherspoon, Adam F. Cunningham, Timothy J. Wells, Pooja Sridhar, Dema Alodaini, Trevor Lithgow, Faye C. Morris, Christopher Icke, Vassiliy N. Bavro, Jack A. Bryant, Douglas F. Browning, Alvin C. K. Teo, Gabriela Boelter, Shu-Sin Chng, Timothy J. Knowles, David I. Roper, Douglas G. Ward, Mark Jeeves, Amanda E. Rossiter, Emily C. A. Goodall, Kara A. Staunton, Manuel Banzhaf, Michael Overduin, Zhi-Soon Chong, I.R. Henderson, Eva Heinz, Yanina R. Sevastsyanovich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::782a6e0b49b139b7ea6dd079a126f816
https://doi.org/10.7554/elife.62614.sa2
https://doi.org/10.7554/elife.62614.sa2
Autor:
Adam Colyer, Vassiliy N. Bavro, Gabriela Boelter, Riyaz Maderbocus, Douglas G. Ward, Peter J. Wotherspoon, Timothy J. Wells, Kara A. Staunton, Alvin C. K. Teo, S-S. Chng, David I. Roper, Faye C. Morris, Michael Overduin, Adam F. Cunningham, Dema Alodaini, Yanina R. Sevastsyanovich, Eva Heinz, Z-S. Chong, Pooja Sridhar, Timothy J. Knowles, I.R. Henderson, Jack A. Bryant, Douglas F. Browning, Mark Jeeves, Christopher Icke, Manuel Banzhaf, Trevor Lithgow
Publikováno v:
bioRxiv
BioRxiv
BioRxiv
The Gram-negative outer membrane envelops the bacterium and functions as a permeability barrier against antibiotics, detergents and environmental stresses. Some virulence factors serve to maintain the integrity of the outer membrane, including DolP (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c441f729408c3b9771dee9a1762e23
https://doi.org/10.1101/2020.08.10.244616
https://doi.org/10.1101/2020.08.10.244616
Autor:
Sophie J. Hesketh, Zoe Stroud, Alvin C. K. Teo, Timothy R. Dafforn, Sarah C. Lee, Corinne J. Smith, David I. Roper, Timothy J. Knowles, Corinne M. Spickett, Megha Rai, Pooja Sridhar, J. Malcolm East, Mayuriben J. Parmar, Stephen P Muench, Kailene S. Simon, Richard Collins, Vincent L. G. Postis, Saskia E. Bakker, C. Howard Barton, Naomi L. Pollock, Gregory Hurlbut
Most membrane proteins function through interactions with other proteins in the phospholipid bilayer, the cytosol or the extracellular milieu. Understanding the molecular basis of these interactions is key to understanding membrane protein function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4184bd5543023d4d506e72952b00801a
Autor:
Alvin C. K. Teo, David I. Roper, Corinne M. Spickett, Timothy R. Dafforn, Naomi L. Pollock, Andrew R. Pitt, Sarah C. Lee, Zoe Stroud, Alpesh Thakker, Stephen Hall
Publikováno v:
Teo, A C K, Lee, S C, Pollock, N L, Stroud, Z, Hall, S, Thakker, A, Pitt, A R, Dafforn, T R, Spickett, C M & Roper, D I 2019, ' Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein ', Scientific Reports, vol. 9, no. 1, 1813 . https://doi.org/10.1038/s41598-018-37962-0
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Biological characterisation of membrane proteins lags behind that of soluble proteins. This reflects issues with the traditional use of detergents for extraction, as the surrounding lipids are generally lost, with adverse structural and functional co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b5a04fd3eca58322285ab4752429ae
https://doi.org/10.1038/s41598-018-37962-0
https://doi.org/10.1038/s41598-018-37962-0