Spatially Resolved Molecular Characterization of Noninvasive Follicular Thyroid Neoplasms with Papillary-like Nuclear Features (NIFTPs) Identifies a Distinct Proteomic Signature Associated with RAS-Mutant Lesions.

Autor: Denti V; Proteomics and Metabolomics Unit, Department of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy., Greco A; Department of Medicine and Surgery, Pathology, Center of Digital Medicine, University of Milano-Bicocca, Fondazione IRCCS San Gerardo dei Tintori, Via Cadore 48, 20900 Monza, Italy., Alviano AM; Department of Medicine and Surgery, Pathology, Center of Digital Medicine, University of Milano-Bicocca, Fondazione IRCCS San Gerardo dei Tintori, Via Cadore 48, 20900 Monza, Italy., Capitoli G; Bicocca Bioinformatics Biostatistics and Bioimaging Research Centre-B4, Department of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy., Monza N; Proteomics and Metabolomics Unit, Department of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy., Smith A; Proteomics and Metabolomics Unit, Department of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy., Pilla D; Department of Medicine and Surgery, Pathology, Center of Digital Medicine, University of Milano-Bicocca, Fondazione IRCCS San Gerardo dei Tintori, Via Cadore 48, 20900 Monza, Italy., Maggioni A; Department of Medicine and Surgery, Pathology, Center of Digital Medicine, University of Milano-Bicocca, Fondazione IRCCS San Gerardo dei Tintori, Via Cadore 48, 20900 Monza, Italy., Ivanova M; Department of Pathology and Laboratory Medicine, European Institute of Oncology IRCCS, 20141 Milan, Italy., Venetis K; Department of Pathology and Laboratory Medicine, European Institute of Oncology IRCCS, 20141 Milan, Italy., Maffini F; Department of Pathology and Laboratory Medicine, European Institute of Oncology IRCCS, 20141 Milan, Italy., Garancini M; Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy., Pincelli AI; Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy., Galimberti S; Bicocca Bioinformatics Biostatistics and Bioimaging Research Centre-B4, Department of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.; Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy., Magni F; Proteomics and Metabolomics Unit, Department of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy., Fusco N; Department of Pathology and Laboratory Medicine, European Institute of Oncology IRCCS, 20141 Milan, Italy.; Department of Oncology & Hemato-Oncology, University of Milan, 20122 Milan, Italy., L'Imperio V; Department of Medicine and Surgery, Pathology, Center of Digital Medicine, University of Milano-Bicocca, Fondazione IRCCS San Gerardo dei Tintori, Via Cadore 48, 20900 Monza, Italy., Pagni F; Department of Medicine and Surgery, Pathology, Center of Digital Medicine, University of Milano-Bicocca, Fondazione IRCCS San Gerardo dei Tintori, Via Cadore 48, 20900 Monza, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 06; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 06.