Zobrazeno 1 - 10
of 692
pro vyhledávání: '"Alveolarization"'
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in infants and the most frequent adverse outcome of premature birth, despite major efforts to minimize injury. It is thought to result from aberrant repair response triggered
Externí odkaz:
https://doaj.org/article/14d2c0b7ed394221b5a5bc224f27b244
Autor:
Rachana R. Chandran, Taylor S. Adams, Inamul Kabir, Eunate Gallardo-Vara, Naftali Kaminski, Brigitte N. Gomperts, Daniel M. Greif
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Alveolarization ensures sufficient lung surface area for gas exchange, and during bulk alveolarization in mice (postnatal day [P] 4.5–14.5), alpha-smooth muscle actin (SMA)+ myofibroblasts accumulate, secrete elastin, and lay down alveolar septum.
Externí odkaz:
https://doaj.org/article/b942c13124314f1096ff19c7c8478d5e
Autor:
Krishan G. Jain, Yang Liu, Runzhen Zhao, Preeti J. Muire, Jiwang Zhang, Qun Sophia Zang, Hong-Long Ji
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8723 (2024)
Alveolar type 2 epithelial (AT2) cells synthesize surfactant protein C (SPC) and repair an injured alveolar epithelium. A mutated surfactant protein C gene (SftpcL184Q, Gene ID: 6440) in newborns has been associated with respiratory distress syndrome
Externí odkaz:
https://doaj.org/article/8a50afe4618a4218b6afb02aec2d2906
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Background Acute lung injury is characterized by overwhelmingly elevated PAI-1 in both lung edema fluid and the circulating system. The role of increased PAI-1, encoded by Serpine1 gene, in the regeneration of injured lung epithelium has not
Externí odkaz:
https://doaj.org/article/013c1d4f56174a79b79d8bcf29d2b68d
Autor:
Xueyu Chen, Dongshan Han, Xuan Wang, Xuemei Huang, Zilu Huang, Yijun Liu, Junyan Zhong, Frans J. Walther, Chuanzhong Yang, Gerry T. M. Wagenaar
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Ibuprofen is a nonsteroidal anti-inflammatory drug that is commonly used to stimulate closure of a patent ductus arteriosus (PDA) in very premature infants and may lead to aberrant neonatal lung development and bronchopulmonary dy
Externí odkaz:
https://doaj.org/article/11f3eded1e27400186e965236fe8a969
Akademický článek
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Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-14 (2021)
Abstract Background Recently, the role of several microRNAs (miRNAs or miRs) in pulmonary diseases has been described. The molecular mechanisms by which miR-214 is possibly implicated in bronchopulmonary dysplasia (BPD) have not yet been addressed. H
Externí odkaz:
https://doaj.org/article/8e95aebbdf0344c4b75c30245762b388
Akademický článek
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Akademický článek
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Autor:
Natália de Souza Xavier Costa, Aila Mirtes Teles, Jôse Mára de Brito, Thaís de Barros Mendes Lopes, Renata Calciolari Rossi, Fernanda Magalhães Arantes Costa, Beatriz Mangueira Saraiva-Romanholo, Adenir Perini, Tatiane Katsue Furuya, Alexis Germán Murillo Carrasco, Mariana Matera Veras, Paulo Hilário Nascimento Saldiva, Roger Chammas, Thais Mauad
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 241, Iss , Pp 113821- (2022)
The perinatal period and early infancy are considered critical periods for lung development. During this period, adversities such as environmental exposures, allergic sensitization, and asthma are believed to impact lung health in adulthood. Therefor
Externí odkaz:
https://doaj.org/article/8238763b7fb34eb2be12ccd5fa80ae77