Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Alveolar type 2 cells"'
Autor:
Rui Quan, Chenhong Shi, Yanan Sun, Chengying Zhang, Ran Bi, Yiran Zhang, Xin Bi, Bin Liu, Ziheng Dong, Dekui Jin, Yixuan Li
Publikováno v:
Engineering, Vol 42, Iss , Pp 74-87 (2024)
Pulmonary fibrosis (PF) is a lethal lung disease that predominantly affects older adults; however, whether and how aging triggers fibrosis remains unclear. To pinpoint the predominant initiating factors of PF, we first analyzed single-cell RNA sequen
Externí odkaz:
https://doaj.org/article/dd15f5916fcc421fa0d0359a7acc27ca
Autor:
Su Wang, Shufen Zhong, Ying Huang, Songling Zhu, Shuangfeng Chen, Ran Wang, Sonam Wangmo, Bo Peng, Houkun Lv, Jichao Yang, Liyan Ma, Zhiyang Ling, Yaguang Zhang, Pengfei Sui, Bing Sun
Publikováno v:
Journal of Innate Immunity, Vol 16, Iss 1, Pp 397-412 (2024)
Introduction: MDM2 is known as the primary negative regulator of p53, and MDM2 promotes lung cancer fibrosis and lung injury through p53-dependent and p53-independent pathways. However, the mechanism by which MDM2 influences the pathogenesis of asthm
Externí odkaz:
https://doaj.org/article/824f3d6dab2643d292de67f3612b2047
Autor:
Daisuke Taniguchi, Mohammadali Ahmadipour, Anthony L. Eiliazadeh, Pascal Duchesneau, Takeshi Nagayasu, Siba Haykal, Golnaz Karoubi, Thomas K. Waddell
Publikováno v:
Regenerative Therapy, Vol 25, Iss , Pp 92-100 (2024)
Objectives: Tissue engineering approaches via repopulation of acellular biological grafts provide an exciting opportunity to generate lung grafts for transplantation. Alveolar type 2 (AT2) cells are a promising cell source for re-epithelialization. T
Externí odkaz:
https://doaj.org/article/d042207d3e274733b0abfdcc55ff0d5a
Publikováno v:
Mathematics, Vol 12, Iss 10, p 1573 (2024)
Transmission electron microscopy imaging provides a unique opportunity to inspect the detailed structure of infected lung cells with SARS-CoV-2. Unlike previous studies, this novel study aims to investigate COVID-19 classification at the lung cellula
Externí odkaz:
https://doaj.org/article/71266c61ce4742b28e3ae60de3602532
Akademický článek
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Autor:
Linghuan Zhang, Wenping Luo, Jiang Liu, Maozhu Xu, Qi Peng, Wenjing Zou, Jingyi You, Yi Shu, Piao Zhao, William Wagstaff, Guozhi Zhao, Kevin Qin, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Yang Bi, Tianyu Zhao, Tong-Chuan He, Zhou Fu
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Background A healthy alveolar epithelium is critical to the gas exchange function of the lungs. As the major cell type of alveolar epithelium, alveolar type 2 (AT2) cells play a critical role in maintaining pulmonary homeostasis by serving a
Externí odkaz:
https://doaj.org/article/eb81371f8db944edb708742645fa38e7
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3034 (2023)
Lung diseases rank third in terms of mortality and represent a significant economic burden globally. Scientists have been conducting research to better understand respiratory diseases and find treatments for them. An ideal in vitro model must mimic t
Externí odkaz:
https://doaj.org/article/45b7e95df37440f79db0be0251a7e891
Autor:
Xiaofan Lai, Shaojie Huang, Sijia Lin, Lvya Pu, Yaqing Wang, Yingying Lin, Wenqi Huang, Zhongxing Wang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive deadly fibrotic lung disease with high prevalence and mortality worldwide. The therapeutic potential of mesenchymal stem cells (MSCs) in pulmonary fibrosis may be at
Externí odkaz:
https://doaj.org/article/9ff9973e39834b47bca22bd363c85f0b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Kun-Feng Tsai, Chen-Jung Shen, Chi-Wai Cheung, Tzong-Luen Wang, Louis W. C. Chow, Yuk-Man Leung, Kar-Lok Wong
Publikováno v:
Chinese Journal of Physiology, Vol 64, Iss 6, Pp 289-297 (2021)
Palmitic acid (PA) is a saturated free fatty acid which, when being excessive, accounts for lipotoxicity. Using human lung A549 cells as a model for lung alveolar type 2 epithelial cells, we found that challenge of A549 cells with PA resulted in apop
Externí odkaz:
https://doaj.org/article/ee6e6b3fc25541dca2230033d8c2a4a3