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Impact of fetal treatments for congenital diaphragmatic hernia on lung development

Autor: Mar Janna Dahl, Anna Lavizzari, Jonathan W. Davis, Peter B. Noble, Raffaele Dellacà, J. Jane Pillow

The extent of lung hypoplasia impacts the survival and severity of morbidities associated with congenital diaphragmatic hernia (CDH). The alveoli of CDH infants and in experimental models of CDH have thickened septa with fewer type II pneumocytes and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12b9f6584dc818a897dbff811912d37
http://hdl.handle.net/11311/1220531

Hoxd10 Is Required Systemically for Secretory Activation in Lactation and Interacts Genetically with Hoxd9

Autor: Ricardo Moraes, Ellen M Carpenter, John D. Landua, Michael T. Lewis

Publikováno v: Journal of Mammary Gland Biology and Neoplasia

Targeted disruption of the murine Hoxd10 gene (ΔHoxd10) leads to a high frequency of localized (gland-to-gland or regionally within a gland) lactation impairment in homozygous mutant mice as a single gene mutation. The effect of Hoxd10 disruption wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87dd5c56c8abab9efdfc5102c588add6
https://pubmed.ncbi.nlm.nih.gov/32705545

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Pulmonary alveolar type I cell population consists of two distinct subtypes that differ in cell fate

Autor: Huanwei Huang, Chengwei Zhang, Nan Tang, Huaping Dai, Jiao Li, Yuanyuan Yu, Zheng Wang, Tao Cai, Juan Li, Zan Tang, Fengchao Wang, Yanjie Wang

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 10
Proceedings of the National Academy of Sciences of the United States of America

Significance Pulmonary alveolar type I (AT1) cells are essential for the gas-exchange function of lungs. AT1 cells retain their cellular plasticity during injury-induced alveolar regeneration. However, we know very little about the developmental hete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d64920b0bc659df0f3376135d9ab1a
https://escholarship.org/uc/item/5722773z