Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alvaro San Millán"'
Autor:
J. Carlos R. Hernandez-Beltran, Jerónimo Rodríguez-Beltrán, Oscar Bruno Aguilar-Luviano, Jesús Velez-Santiago, Octavio Mondragón-Palomino, R. Craig MacLean, Ayari Fuentes-Hernández, Alvaro San Millán, Rafael Peña-Miller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The rise of antibiotic resistance is a critical public health concern, requiring an understanding of mechanisms that enable bacteria to tolerate antimicrobial agents. Bacteria use diverse strategies, including the amplification of drug-resis
Externí odkaz:
https://doaj.org/article/e03a6d9559a543168547e6a8826f40dc
Autor:
Aida Alonso-del Valle, Ricardo León-Sampedro, Jerónimo Rodríguez-Beltrán, Javier DelaFuente, Marta Hernández-García, Patricia Ruiz-Garbajosa, Rafael Cantón, Rafael Peña-Miller, Alvaro San Millán
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The variability of plasmid fitness effects on wild-type bacterial hosts have been largely unknown until this study, which shows that plasmid persistence increases with bacterial diversity and becomes less dependent on conjugation. This could explain
Externí odkaz:
https://doaj.org/article/46212f3f45ec448aae37660a0d2c7cb6
Autor:
José Carlos Ramón Hernández-Beltrán, Alvaro San Millán, Ayari Fuentes-Hernández, Rafael Peña-Miller
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
With plasmid-mediated antibiotic resistance thriving and threatening to become a serious public health problem, it is paramount to increase our understanding of the forces that enable the spread and maintenance of drug resistance genes encoded in mob
Externí odkaz:
https://doaj.org/article/be581ed7cbe14db6bedb0cd57562654a
Autor:
Fernando Baquero, José-Luis Martínez, Alvaro Sánchez, Miguel D. Fernández-de-Bobadilla, Alvaro San-Millán, Jerónimo Rodríguez-Beltrán
Publikováno v:
Biology. 12:640
Epistasis refers to the way in which genetic interactions between some genetic loci affect phenotypes and fitness. In this study, we propose the concept of “structural epistasis” to emphasize the role of the variable physical interactions between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153714d0911515a54b3fe81a11582ac2
https://doi.org/10.3390/biology12050640
https://doi.org/10.3390/biology12050640
Autor:
Cristina Herencias, Laura Álvaro-Llorente, Paula Ramiro-Martínez, Ariadna Fernández-Calvet, Ada Muñoz-Cazalla, Javier DelaFuente, Fabrice E. Graf, Laura Jaraba-Soto, Juan Antonio Castillo-Polo, Rafael Cantón, Álvaro San Millán, Jerónimo Rodríguez-Beltrán
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Major antibiotic groups are losing effectiveness due to the uncontrollable spread of antimicrobial resistance (AMR) genes. Among these, β-lactam resistance genes –encoding β-lactamases– stand as the most common resistance mechanism in
Externí odkaz:
https://doaj.org/article/4459ee25c64b452a9a925117443935ea
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 311-320 (2024)
Abstract Antimicrobial resistance (AMR) in bacteria is a major public health threat and conjugative plasmids play a key role in the dissemination of AMR genes among bacterial pathogens. Interestingly, the association between AMR plasmids and pathogen
Externí odkaz:
https://doaj.org/article/d4379e71c8324a4c9a554cef7e92ea40
Autor:
Alvaro San Millán
Publikováno v:
REDIUMH. Depósito Digital de la UMH
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8966ea4926d6e3fe7500bec3dafc7a95
http://hdl.handle.net/11000/5748
http://hdl.handle.net/11000/5748
Autor:
Suzanne Humphrey, Álvaro San Millán, Macarena Toll-Riera, John Connolly, Alejandra Flor-Duro, John Chen, Carles Ubeda, R. Craig MacLean, José R. Penadés
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Many plasmids can be transferred between bacterial cells via conjugation; however, the mechanisms underlying the transfer of non-conjugative plasmids are less clear. Here, Humphrey et al. show that staphylococcal phages and a family of pathogenicity
Externí odkaz:
https://doaj.org/article/223838baccfd4b7e90e35bc7462be767
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001308 (2021)
The horizontal transfer of mobile DNA is one of the signature moves of bacterial evolution, but the specific rules that govern this transfer remain elusive. In this PLOS Biology issue, Haudiquet and colleagues revealed that the interactions between m
Externí odkaz:
https://doaj.org/article/2dc4f7298eb641a883de708e610e33d2
Autor:
Cristina Herencias, Jerónimo Rodríguez-Beltrán, Ricardo León-Sampedro, Aida Alonso-del Valle, Jana Palkovičová, Rafael Cantón, Álvaro San Millán
Publikováno v:
eLife, Vol 10 (2021)
Collateral sensitivity (CS) is a promising alternative approach to counteract the rising problem of antibiotic resistance (ABR). CS occurs when the acquisition of resistance to one antibiotic produces increased susceptibility to a second antibiotic.
Externí odkaz:
https://doaj.org/article/c2d0354829ac479db07608ff95e9568f