Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alvaro Roman-Fernandez"'
Autor:
Konstantina Nikolatou, Emma Sandilands, Alvaro Roman-Fernandez, Erin M. Cumming, Eva C. Freckmann, Sergio Lilla, Lori Buetow, Lynn McGarry, Matthew Neilson, Robin Shaw, David Strachan, Crispin Miller, Danny T Huang, Ian McNeish, James C. Norman, Sara Zanivan, David M Bryant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3558da1a05c3ad0c5ac2fe3772e9e225
https://doi.org/10.15252/rc.2023374128
https://doi.org/10.15252/rc.2023374128
Autor:
Eva C. Freckmann, Emma Sandilands, Erin Cumming, Matthew Neilson, Alvaro Román-Fernández, Konstantina Nikolatou, Marisa Nacke, Tamsin R. M. Lannagan, Ann Hedley, David Strachan, Mark Salji, Jennifer P. Morton, Lynn McGarry, Hing Y. Leung, Owen J. Sansom, Crispin J. Miller, David M. Bryant
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
There are currently a lack of tools to detect heterogeneity in 3D cultures. Here the authors report Traject3d as a framework to identify heterogeneous states in 3D culture and to understand how these give rise to distinct phenotypes using label-free
Externí odkaz:
https://doaj.org/article/d1ea5c3909d0472cb9c9c41a696d4ec5
Autor:
Marisa Nacke, Emma Sandilands, Konstantina Nikolatou, Álvaro Román-Fernández, Susan Mason, Rachana Patel, Sergio Lilla, Tamas Yelland, Laura C. A. Galbraith, Eva C. Freckmann, Lynn McGarry, Jennifer P. Morton, Emma Shanks, Hing Y. Leung, Elke Markert, Shehab Ismail, Sara Zanivan, Karen Blyth, David M. Bryant
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
The signalling pathways underpinning cell growth and invasion use overlapping components, yet how mutually exclusive responses occur is unclear. Here, the authors show that alternate isoforms of the ARF GTPase exchange factor IQSEC1 direct phosphoino
Externí odkaz:
https://doaj.org/article/5313ed90f36c4817a2437ea2428b588c
Autor:
Máté Nászai, Karen Bellec, Yachuan Yu, Alvaro Román-Fernández, Emma Sandilands, Joel Johansson, Andrew D Campbell, Jim C Norman, Owen J Sansom, David M Bryant, Julia B Cordero
Publikováno v:
eLife, Vol 10 (2021)
RAS-like (RAL) GTPases function in Wnt signalling-dependent intestinal stem cell proliferation and regeneration. Whether RAL proteins work as canonical RAS effectors in the intestine and the mechanisms of how they contribute to tumourigenesis remain
Externí odkaz:
https://doaj.org/article/d5581e9d01e64d7795bb78b98f7139a1
Autor:
Álvaro Román-Fernández, Julie Roignot, Emma Sandilands, Marisa Nacke, Mohammed A. Mansour, Lynn McGarry, Emma Shanks, Keith E. Mostov, David M. Bryant
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
During de novo establishment of apical-basal polarity, a basolateral membrane must be converted into an apical delivery zone. Here, the authors use MDCK 3D cysts to uncover that the phospholipid PI(3,4)P2 is an apical membrane determinant.
Externí odkaz:
https://doaj.org/article/e0c77c25596d44b6bed03dae472c2b55