Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alvaro R. B. Prieto da Silva"'
Autor:
Adriana da Costa-Neves, Irina Kerkis, Eduardo Osório Frare, Alvaro R. B. Prieto da Silva, Nicole Caroline Mambelli-Lisboa
Publikováno v:
Cell Biology International. 44:1184-1192
Conditioned medium (CM) (cell secretome) is a cocktail of growth factors, cytokines, and other soluble mediators secreted by cells into a culture medium. These growth factors are fundamental in many cellular processes such as cell growth, differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e53c6d257edf953cf1ab57a505c35f
https://doi.org/10.1002/cbin.11317
https://doi.org/10.1002/cbin.11317
Autor:
Alba F C Torres, Chen Huang, Cheong-Meng Chong, Siu Wai Leung, Alvaro R B Prieto-da-Silva, Alexandre Havt, Yves P Quinet, Alice M C Martins, Simon M Y Lee, Gandhi Rádis-Baptista
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87556 (2014)
BACKGROUND: Dinoponera quadriceps is a predatory giant ant that inhabits the Neotropical region and subdues its prey (insects) with stings that deliver a toxic cocktail of molecules. Human accidents occasionally occur and cause local pain and systemi
Externí odkaz:
https://doaj.org/article/7ad82a2ead9e4b77a817bda1e55f7fd3
Autor:
Jan Tytgat, Irina Kerkis, Celine Pompeia, Paulo Luiz de Sá Júnior, Alvaro R. B. Prieto da Silva
Publikováno v:
Cellular and Molecular Life Sciences. 74:647-661
Toxins have been shown to have many biological functions and to constitute a rich source of drugs and biotechnological tools. We focus on toxins that not only have a specific activity, but also contain residues responsible for transmembrane penetrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66e8d39123617ff9954fc882a33149a
https://doi.org/10.1007/s00018-016-2343-6
https://doi.org/10.1007/s00018-016-2343-6
Autor:
Juliana Mozer Sciani, Nicole Caroline Mambelli-Lisboa, Alvaro R. B. Prieto da Silva, Irina Kerkis
Publikováno v:
Molecules; Volume 23; Issue 4; Pages: 968
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Crotamine is a highly cationic; cysteine rich, cross-linked, low molecular mass cell penetrating peptide (CPP) from the venom of the South American rattlesnake. Potential application of crotamine in biomedicine may require its large-scale purificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffc769e332ce574dedad4ef22a63b24
https://doi.org/10.3390/molecules23040968
https://doi.org/10.3390/molecules23040968
Autor:
Mirian A. F. Hayashi, Alexandre Kerkis, Irina Kerkis, Gandhi Rádis Baptista, Yamane Tetsuo, Alvaro R. B. Prieto da Silva
Publikováno v:
Journal of the Brazilian Chemical Society. 19:211-225
Today, different functional classes of bioactive peptides and toxins isolated from diverse sources of living organisms are known. In medicine, these polypeptides present the potential to be used structurally unmodified or to serve as templates for mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4600fdc97e912b4006a5f4ae5aa981c
https://doi.org/10.1590/s0103-50532008000200004
https://doi.org/10.1590/s0103-50532008000200004
Autor:
Alexandre Pereira, Tetsuo Yamane, Paulo Luiz de Sá Júnior, André J. Zaharenko, Mirian A. F. Hayashi, Gandhi Rádis-Baptista, Alvaro R. B. Prieto da Silva, Irina Kerkis, Alexandre Kerkis
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2014 (2014)
BioMed Research International, Vol 2014 (2014)
Animal venoms comprise a naturally selected cocktail of bioactive peptides/proteins and other molecules, each of which playing a defined role thanks to the highly specific interactions with diverse molecular targets found in the prey. Research focuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2117edc08de98d4b699751d830e29233
http://europepmc.org/articles/PMC3914522
http://europepmc.org/articles/PMC3914522
Autor:
Maria de Fátima D. Furtado, Margaret H. Magdesian, Alvaro R. B. Prieto da Silva, Tetsuo Yamane, Paulo L. Ho
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 118:7-11
Eukaryote genomes are endowed with varying quantities of repeated DNA families. These families show different patterns of conservation among species, copy numbers, chromosomal distribution, and transcription. Characterization of repeated DNA sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6be3b5eb3bbde705b64af1a2c0f67ad
https://doi.org/10.1016/s0305-0491(97)00004-7
https://doi.org/10.1016/s0305-0491(97)00004-7
Autor:
Camila M. Yonamine, Antonio José Lapa, Iuri E. Gouvea, Marcia Y. Kondo, Luiz Juliano, Debora Okamoto, Marcela B. Nering, Alvaro R. B. Prieto da Silva, Maria A. Juliano, Douglas Andrade, Mirian A. F. Hayashi, José Alberto A. da Silva, Tetsuo Yamane, Maria Teresa R. Lima-Landman
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 79
Gyroxin is a serine protease displaying a thrombin-like activity found in the venom of the South American rattlesnake Crotalus durissus terrificus. Typically, intravenous injection of purified gyroxin induces a barrel rotation syndrome in mice. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7109b65976cd04acae90326e3310721d
https://pubmed.ncbi.nlm.nih.gov/24412460
https://pubmed.ncbi.nlm.nih.gov/24412460
Autor:
Aparecida Santo Pietro Pereira, Tetsuo Yamane, Eduardo B. Oliveira, Alexandre Kerkis, Alvaro R. B. Prieto da Silva, Fernando de Sá Silva, Irina Kerkis, Gandhi Rádis-Baptista, A. Pereira, Mirian A. F. Hayashi
Publikováno v:
Expert opinion on investigational drugs. 20(9)
Selective anticancer cell activity for both cell-penetrating and cationic antimicrobial peptides has previously been reported. As crotamine possesses activities similar to both of these, this study investigates crotamine's anticancer toxicity in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da4cffe62ac39e25a9e6aee3bb9b020
https://pubmed.ncbi.nlm.nih.gov/21834748
https://pubmed.ncbi.nlm.nih.gov/21834748
Autor:
Tetsuo Yamane, Maria Emilia M. T. Walter, Alvaro R. B. Prieto da Silva, Marcelo M. Brigido, Jorge Luiz López-Lozano, Spartaco Astolfi-Filho, Fabricio B. M. Arraes, Gandhi Rádis-Baptista, Jonso Vieira de Souza, Márcia Neiva
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 53(4)
Bothrops atrox is a highly dangerous pit viper in the Brazilian Amazon region. We produced a global catalogue of gene transcripts to identify the main toxin and other protein families present in the B. atrox venom gland. We prepared a directional cDN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1bed84b8d38dc17513c923fbf22e1d
https://pubmed.ncbi.nlm.nih.gov/19708221
https://pubmed.ncbi.nlm.nih.gov/19708221