Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Alvaro Morales-Molina"'
Autor:
Alvaro Morales-Molina, Miguel Angel Rodriguez-Milla, Patricia Garcia-Rodriguez, Laura Hidalgo, Ramon Alemany, Javier Garcia-Castro
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200863- (2024)
Oncolytic viruses often face challenges in achieving optimal antitumor immunity as standalone therapies. The penton base RGD-integrin interactions play a significant role in wild-type adenovirus-induced innate immune responses. To modify these respon
Externí odkaz:
https://doaj.org/article/f889f634fb8d45d19137a418f077a9bb
Autor:
Marion Rabé, Lucie Fonteneau, Lisa Oliver, Alvaro Morales-Molina, Camille Jubelin, Javier Garcia-Castro, Dominique Heymann, Catherine Gratas, François M. Vallette
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
We have observed a drug-tolerant/persister state in a human glioblastoma (GBM) cell line after exposure to temozolomide, the standard-of-care chemotherapeutic agent for GBM. We used a multicolor lentiviral genetic barcode labeling to follow cell popu
Externí odkaz:
https://doaj.org/article/af10a72ecb07478da8fef7c1d545335e
Combination immunotherapy using G-CSF and oncolytic virotherapy reduces tumor growth in osteosarcoma
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Osteosarcoma is the most common malignant solid tumor that affects bones, however, survival rates of patients with relapsed osteosarcoma have not improved in the last 30 years. Oncolytic virotherapy, which uses viruses designed to selectiv
Externí odkaz:
https://doaj.org/article/3b8f004cf8c74124b047b48a25e72609
Autor:
Laura Hidalgo, Beatriz Somovilla-Crespo, Patricia Garcia-Rodriguez, Alvaro Morales-Molina, Miguel Angel Rodriguez-Milla, Javier Garcia-Castro
Immunotherapy with chimeric antigen receptor T (CAR T) cells has changed the treatment of hematological malignances, but they are still a challenge for solid tumors, including pediatric sarcomas. Here, we report a switchable CAR T cell strategy based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b70ca9c71dde46e3a2f04607de8e368
https://hdl.handle.net/20.500.12105/16059
https://hdl.handle.net/20.500.12105/16059
Autor:
Javier García-Castro, María-Luisa Gaspar, Belén de Andrés, Teresa Cejalvo, Stefano Gambera, Miguel Ángel Rodriguez-Milla, Alvaro Morales-Molina
OAd-MSC WT and OAd-MSC TLR4−/− show similar expression of cell membrane receptors in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965b3a90bdea7a868749e3c5134a8507
https://doi.org/10.1158/2767-9764.22546928.v1
https://doi.org/10.1158/2767-9764.22546928.v1
Autor:
Javier García-Castro, María-Luisa Gaspar, Belén de Andrés, Teresa Cejalvo, Stefano Gambera, Miguel Ángel Rodriguez-Milla, Alvaro Morales-Molina
OAd-MSC MyD88−/−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2153898f6741148ba5122a2be112bd3
https://doi.org/10.1158/2767-9764.22546904.v1
https://doi.org/10.1158/2767-9764.22546904.v1
Autor:
Javier García-Castro, María-Luisa Gaspar, Belén de Andrés, Teresa Cejalvo, Stefano Gambera, Miguel Ángel Rodriguez-Milla, Alvaro Morales-Molina
Cancer immunotherapy aims to activate the immune system. Some immunotherapeutic agents can be loaded in carrier cells for delivering to the tumors. However, a challenge with cell-based therapies is the selection of the appropriate cells to produce ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1647c5eb47c1e2d1972e01fd4b26a24e
https://doi.org/10.1158/2767-9764.c.6551258
https://doi.org/10.1158/2767-9764.c.6551258
Autor:
Ramon Alemany, Javier García-Castro, Ahmed Abdullah Al-Zaher, Alvaro Morales-Molina, Ana Judith Perisé-Barrios, Marti Farrera-Sal, Carlos Alberto Fajardo, Rafael Moreno
Several studies have evaluated the efficacy of using human oncolytic adenovirus (OAdv)–loaded mesenchymal stem cells (MSC) for cancer treatment. For example, we have described the antitumor efficacy of CELYVIR, autologous bone marrow–mesenchymal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0822741e856a3939ad29d9d6262c004
https://doi.org/10.1158/1535-7163.c.6537970.v1
https://doi.org/10.1158/1535-7163.c.6537970.v1
Autor:
Ramon Alemany, Javier García-Castro, Ahmed Abdullah Al-Zaher, Alvaro Morales-Molina, Ana Judith Perisé-Barrios, Marti Farrera-Sal, Carlos Alberto Fajardo, Rafael Moreno
Supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9bf44aabc56ffdfd3234979e4039d8
https://doi.org/10.1158/1535-7163.22505149
https://doi.org/10.1158/1535-7163.22505149
Autor:
Ramon Alemany, Javier García-Castro, Ahmed Abdullah Al-Zaher, Alvaro Morales-Molina, Ana Judith Perisé-Barrios, Marti Farrera-Sal, Carlos Alberto Fajardo, Rafael Moreno
Supplementary Figure 1. Cytokine array; Supplementary Figure 2. Effect of TLR-9 knock-down on OAd-infected MenSCs properties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6295ce5810b02360f4f4522ea50cd51
https://doi.org/10.1158/1535-7163.22505152
https://doi.org/10.1158/1535-7163.22505152