Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Alvaro Martinez-Barrio"'
Autor:
Andrey Höglund, Rie Henriksen, Allison M Churcher, Carlos M Guerrero-Bosagna, Alvaro Martinez-Barrio, Martin Johnsson, Per Jensen, Dominic Wright
Publikováno v:
PLoS Genetics, Vol 20, Iss 3, p e1010719 (2024)
DNA methylation is a key regulator of eukaryote genomes, and is of particular relevance in the regulation of gene expression on the sex chromosomes, with a key role in dosage compensation in mammalian XY systems. In the case of birds, dosage compensa
Externí odkaz:
https://doaj.org/article/8e0367e0a1834a1e8cd831ae52e1ba77
Autor:
Chen-Shan Chin, Justin Wagner, Qiandong Zeng, Erik Garrison, Shilpa Garg, Arkarachai Fungtammasan, Mikko Rautiainen, Sergey Aganezov, Melanie Kirsche, Samantha Zarate, Michael C. Schatz, Chunlin Xiao, William J. Rowell, Charles Markello, Jesse Farek, Fritz J. Sedlazeck, Vikas Bansal, Byunggil Yoo, Neil Miller, Xin Zhou, Andrew Carroll, Alvaro Martinez Barrio, Marc Salit, Tobias Marschall, Alexander T. Dilthey, Justin M. Zook
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Accurate, phased assemblies are a key tool in understanding the human genome, particularly in highly polymorphic regions like the medically important MHC. Here the authors provide an assembly-based benchmark for this difficult-to-characterize region.
Externí odkaz:
https://doaj.org/article/5e9e6d5734354b4a86ef752be8c0d26e
Autor:
Justin Wagner, Nathan D. Olson, Lindsay Harris, Ziad Khan, Jesse Farek, Medhat Mahmoud, Ana Stankovic, Vladimir Kovacevic, Byunggil Yoo, Neil Miller, Jeffrey A. Rosenfeld, Bohan Ni, Samantha Zarate, Melanie Kirsche, Sergey Aganezov, Michael C. Schatz, Giuseppe Narzisi, Marta Byrska-Bishop, Wayne Clarke, Uday S. Evani, Charles Markello, Kishwar Shafin, Xin Zhou, Arend Sidow, Vikas Bansal, Peter Ebert, Tobias Marschall, Peter Lansdorp, Vincent Hanlon, Carl-Adam Mattsson, Alvaro Martinez Barrio, Ian T. Fiddes, Chunlin Xiao, Arkarachai Fungtammasan, Chen-Shan Chin, Aaron M. Wenger, William J. Rowell, Fritz J. Sedlazeck, Andrew Carroll, Marc Salit, Justin M. Zook
Publikováno v:
Cell genomics. 2(5)
Genome in a Bottle benchmarks are widely used to help validate clinical sequencing pipelines and develop variant calling and sequencing methods. Here we use accurate linked and long reads to expand benchmarks in 7 samples to include difficult-to-map
Autor:
Adriano Tullo, Francesca Mancini, Alessio Aboudan, Fabio Calantropio, Alvaro Martinez Barrio, Andrea Pacifici, Gian Gabriele Ori
Introduction: This abstract deals with analysing the interaction between the ExoMars lander and the surface deformation at the touchdown in the Oxia Planum region of Mars. The analysis of ExoMars landing has been conducted by IRSPS under Thales Aleni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::030de199ab1970a85ea5259e55a4f3e1
https://doi.org/10.5194/epsc2022-249
https://doi.org/10.5194/epsc2022-249
Autor:
Alvaro Martinez Barrio, Sangeet Lamichhaney, Guangyi Fan, Nima Rafati, Mats Pettersson, He Zhang, Jacques Dainat, Diana Ekman, Marc Höppner, Patric Jern, Marcel Martin, Björn Nystedt, Xin Liu, Wenbin Chen, Xinming Liang, Chengcheng Shi, Yuanyuan Fu, Kailong Ma, Xiao Zhan, Chungang Feng, Ulla Gustafson, Carl-Johan Rubin, Markus Sällman Almén, Martina Blass, Michele Casini, Arild Folkvord, Linda Laikre, Nils Ryman, Simon Ming-Yuen Lee, Xun Xu, Leif Andersson
Publikováno v:
eLife, Vol 5 (2016)
Ecological adaptation is of major relevance to speciation and sustainable population management, but the underlying genetic factors are typically hard to study in natural populations due to genetic differentiation caused by natural selection being co
Externí odkaz:
https://doaj.org/article/6a1c8f44e277485c8ccd4757a747192d
Autor:
Jacques Dainat, David Berger, Ahmed Sayadi, Björn Nystedt, Alvaro Martinez Barrio, Elina Immonen, Christian Tellgren-Roth, Göran Arnqvist
Publikováno v:
Nature Ecology & Evolution. 3:1725-1730
Genes with sex-biased expression show a number of unique properties and this has been seen as evidence for conflicting selection pressures in males and females, forming a genetic ‘tug-of-war’ between the sexes. However, we lack studies of taxa wh
Autor:
Aisha Souquette, Stefan A. Schattgen, Alvaro Martinez Barrio, Michael J. T. Stubbington, Jeremy Chase Crawford, Paul G. Thomas, Kate Guion, Philip Bradley
Publikováno v:
Nat Biotechnol
Links between T cell clonotypes, as defined by T cell receptor (TCR) sequences, and phenotype, as reflected in gene expression profiles, surface protein expression, and peptide:MHC binding, can reveal functional relationships beyond the features shar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d39fe4d639c690c40cdaa3a8feb3fc
https://europepmc.org/articles/PMC8832949/
https://europepmc.org/articles/PMC8832949/
Autor:
Justin Wagner, Nathan D Olson, Lindsay Harris, Jennifer McDaniel, Ziad Khan, Jesse Farek, Medhat Mahmoud, Ana Stankovic, Vladimir Kovacevic, Byunggil Yoo, Neil Miller, Jeffrey A. Rosenfeld, Bohan Ni, Samantha Zarate, Melanie Kirsche, Sergey Aganezov, Michael Schatz, Giuseppe Narzisi, Marta Byrska-Bishop, Wayne Clarke, Uday S. Evani, Charles Markello, Kishwar Shafin, Xin Zhou, Arend Sidow, Vikas Bansal, Peter Ebert, Tobias Marschall, Peter Lansdorp, Vincent Hanlon, Carl-Adam Mattsson, Alvaro Martinez Barrio, Ian T Fiddes, Chunlin Xiao, Arkarachai Fungtammasan, Chen-Shan Chin, Aaron M Wenger, William J Rowell, Fritz J Sedlazeck, Andrew Carroll, Marc Salit, Justin M Zook
Genome in a Bottle (GIAB) benchmarks have been widely used to help validate clinical sequencing pipelines and develop new variant calling and sequencing methods. Here we use accurate long and linked reads to expand the prior benchmark to include diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14678663722fe5e769c2ec1a43316dbd
https://doi.org/10.1101/2020.07.24.212712
https://doi.org/10.1101/2020.07.24.212712
Autor:
Stefan A. Schattgen, Jeremy Chase Crawford, Michael J. T. Stubbington, Aisha Souquette, Kate Guion, Paul G. Thomas, Alvaro Martinez Barrio, Philip Bradley
Multi-modal single-cell technologies capable of simultaneously assaying gene expression and surface phenotype across large numbers of immune cells have described extensive heterogeneity within these complex populations, in healthy and diseased states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbd7cabfe2edd16fa7330ea176ed6514
https://doi.org/10.1101/2020.06.04.134536
https://doi.org/10.1101/2020.06.04.134536
Autor:
Marc L. Salit, Andrew Carroll, Shilpa Garg, George M. Church, Arda Soylev, Vincent Huang, Michael C. Schatz, Weichen Zhou, Jennifer R. Davis, John J. Farrell, Rick Tearle, Michael D. Kaiser, Noushin Ghaffari, Aaron M. Wenger, Joyce V. Lee, Justin M. Zook, Shaun D. Jackman, Paul C. Boutros, James C. Mullikin, John S. Oliver, Iman Hajirasouliha, Chunlin Xiao, Jay M. Sage, Alexandre Rouette, Jeffrey A. Rosenfeld, Stephen T. Sherry, Tobias Marschall, Fritz J. Sedlazeck, Noah Alexander, Anthony P. Catalano, Ken Chen, Nathan D. Olson, Nancy F. Hansen, Lesley M. Chapman, Ian T. Fiddes, Sergey Koren, Sayed Mohammad Ebrahim Sahraeian, Adam M. Phillippy, Jeremiah Wala, Noah Spies, Mark Chaisson, Christopher E. Mason, Oscar L. Rodriguez, Adam C. English, Can Alkan, Camir Ricketts, Alvaro Martinez Barrio, Xian Fan, Ali Bashir, Ryan E. Mills
Publikováno v:
Nature Biotechnology
New technologies and analysis methods are enabling genomic structural variants (SVs) to be detected with ever-increasing accuracy, resolution and comprehensiveness. To help translate these methods to routine research and clinical practice, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a39771ab74ef1eb7ec7b8d2f401d644
https://hdl.handle.net/11693/75718.2
https://hdl.handle.net/11693/75718.2