Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alvaro González‐Dominguez"'
Autor:
Alvaro González‐Dominguez, Raúl Montañez, Beatriz Castejón‐Vega, Jéssica Nuñez‐Vasco, Débora Lendines‐Cordero, Chun Wang, Gabriel Mbalaviele, José M Navarro‐Pando, Elísabet Alcocer‐Gómez, Mario D Cordero
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp 1-7 (2021)
Abstract Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS
Externí odkaz:
https://doaj.org/article/741ada3b7d4b430aadbd36423e7df82b
Autor:
Álvaro González-Domínguez, Otto Savolainen, Jesús Domínguez-Riscart, Rikard Landberg, Alfonso Lechuga-Sancho, Raúl González-Domínguez
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Although insulin resistance (IR) is among the most frequent and pathogenically relevant complications accompanying childhood obesity, its role in modulating and exacerbating obesity pathophysiology has not yet been completely clar
Externí odkaz:
https://doaj.org/article/4d8840ecfb0f44599a93513dea5c9ccf
Autor:
Álvaro González-Domínguez, Jesús Domínguez-Riscart, Otto Savolainen, Alfonso Lechuga-Sancho, Rikard Landberg, Raúl González-Domínguez
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background Insulin resistance is a frequent precursor of typical obesity and metabolic syndrome complications. However, accurate diagnosis remains elusive because of its pathophysiological complexity and heterogeneity. Herein, we have explor
Externí odkaz:
https://doaj.org/article/d1c692f6b710470c9027ba6e5fb5e298
Autor:
José M. Navarro-Pando, Débora Lendines-Cordero, Mario D. Cordero, Raúl Montañez, Gabriel Mbalaviele, Alvaro González-Dominguez, Jéssica Nuñez-Vasco, Elísabet Alcocer-Gómez, Beatriz Castejón-Vega, Chun Wang
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine
Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS skin fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b979333b420f912cb3d0a1d04d41ad
Autor:
Álvaro González-Domínguez, Lucía Jurado-Sumariva, Jesús Domínguez-Riscart, Ana Saez-Benito, Raúl González-Domínguez
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Background Family history of obesity is known to increase the odds of developing childhood obesity in the offspring, but its influence in underlying molecular complications remains unexplored. Subjects/Methods Here, we investigated a populat
Externí odkaz:
https://doaj.org/article/751ed374a48045618824a96d7edfffba
Autor:
Álvaro González-Domínguez, Thalía Belmonte, Jesús Domínguez-Riscart, Pablo Ruiz-Ocaña, Inés Muela-Zarzuela, Ana Saez-Benito, Raúl Montañez-Martínez, Rosa M. Mateos, Alfonso M. Lechuga-Sancho
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Insulin resistance (IR) is considered the main driver of obesity related metabolic complications, and is related to oxidative stress and inflammation, which in turn promote each other. There is currently no specific definition of
Externí odkaz:
https://doaj.org/article/e3183f1a486c44a6831df6b055916cf3
Autor:
Gonzalo-Martín Pérez-Arana, Alfredo Díaz-Gómez, José Bancalero-de los Reyes, Manuel Gracia-Romero, Antonio Ribelles-García, Francisco Visiedo, Álvaro González-Domínguez, David Almorza-Gomar, José-Arturo Prada-Oliveira
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The biological activity of glucagon has recently been proposed to both stimulate hepatic glucose production and also include a paradoxical insulinotropic effect, which could suggest a new role of glucagon in the pathophysiology type 2 diabetes mellit
Externí odkaz:
https://doaj.org/article/050a58c0cfb64d2aa61a048c538ab91a
Autor:
Álvaro González-Domínguez, Jesús Domínguez-Riscart, María Millán-Martínez, Alfonso María Lechuga-Sancho, Raúl González-Domínguez
Publikováno v:
Frontiers in Public Health, Vol 10 (2023)
Diet is one of the most important modifiable lifestyle factors for preventing and treating obesity. In this respect, the Mediterranean diet (MD) has proven to be a rich source of a myriad of micronutrients with positive repercussions on human health.
Externí odkaz:
https://doaj.org/article/42de85aaa85e4c5bb3428abe6794b1c3
Autor:
Álvaro González-Domínguez, María Millán-Martínez, Jesús Domínguez-Riscart, Alfonso María Lechuga-Sancho, Raúl González-Domínguez
Publikováno v:
Nutrients, Vol 15, Iss 10, p 2347 (2023)
Background: Trace elements and heavy metals have proven pivotal roles in childhood obesity and insulin resistance. However, growing evidence suggests that insulin resistance could encompass distinct phenotypic subtypes. Methods: Herein, we performed
Externí odkaz:
https://doaj.org/article/e0a4b1892b5849798a4d138a005d134d
Autor:
Álvaro González-Domínguez, María Millán-Martínez, Jesús Domínguez-Riscart, Rosa María Mateos, Alfonso María Lechuga-Sancho, Raúl González-Domínguez
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2439 (2022)
Metals are redox-active substances that participate in central biological processes and may be involved in a multitude of pathogenic events. However, considering the inconsistencies reported in the literature, further research is crucial to disentang
Externí odkaz:
https://doaj.org/article/34795bf213724c8facd9ceeba7397b3f