DEAD-box RNA helicase DDX3 connects CRM1-dependent nuclear export and translation of the HIV-1 unspliced mRNA through its N-terminal domain

Autor: Théophile Ohlmann, Alessandra Dellarossa, Alvaro Fröhlich, Fernando Valiente-Echeverría, Yara Prades-Pérez, Andrea Garcés-Alday, Francisco García-de-Gracia, Bárbara Rojas-Araya, Paulina S. Rubilar, Daniela Toro-Ascuy, Camila Pereira-Montecinos, Ricardo Soto-Rifo

Publikováno v: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, 1859 (5), pp.719-730. ⟨10.1016/j.bbagrm.2016.03.009⟩
BBA-Biochimica et Biophysica Acta, 2016, 1859 (5), pp.719-730. ⟨10.1016/j.bbagrm.2016.03.009⟩

International audience; DEAD-box RNA helicase DDX3 is a host factor essential for HIV-1 replication and thus, a potential target for novel therapies aimed to overcome viral resistance. Previous studies have shown that DDX3 promotes nuclear export and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feeac3c3e210f09964fa16ff315c199d
https://pubmed.ncbi.nlm.nih.gov/27012366