Výsledky vyhledávání - "Alvaro D. Facta"

Improvement in coronary endothelial function is independently associated with a slowed progression of coronary artery calcification in type 2 diabetes mellitus

Autor: Thomas H. Schindler, Heinrich R. Schelbert, Jonathan G. Goldin, Alvaro D. Facta, Manfred Olschewski, Jerson Cadenas, James Sayre, Yanjie Li

Publikováno v: European Heart Journal, Vol. 30, No 24 (2009) pp. 3064-3073

AIMS: To examine a relationship between alterations of structure and function of the arterial wall in response to glucose-lowering therapy in type 2 diabetes mellitus (DM) after a 1-year follow-up (FU). METHODS AND RESULTS: In DM (n = 22) and in heal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708dc62cf5fd6578e5ef2373dbb00f4c
http://doc.rero.ch/record/293307/files/ehp482.pdf

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Improvement in coronary vascular dysfunction produced with euglycaemic control in patients with type 2 diabetes

Autor: Heinrich R. Schelbert, Thomas H. Schindler, Manuel J. Quiñones, Jerson Cadenas, John O. Prior, Alvaro D. Facta, Willa A. Hsueh

Publikováno v: Heart. 93:345-349

To determine the effect of plasma glucose lowering on coronary circulatory function in type 2 diabetes mellitus.Twenty patients with type 2 diabetes and 18 weight-matched controls were studied. At baseline, myocardial blood flow (MBF) was measured wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fcc81540fa8385810b988902fed01c
https://doi.org/10.1136/hrt.2006.094128

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Determinants of myocardial blood flow response to cold pressor testing and pharmacologic vasodilation in healthy humans

Autor: Roxana Campisi, Miguel Hernandez-Pampaloni, Magnus Dahlbom, Thomas H. Schindler, Heinrich R. Schelbert, John O. Prior, Alvaro D. Facta

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 34:20-27

Response of myocardial blood flow (MBF) to sympathetic stimulation with cold is modulated by endothelium-related factors and is typically altered in the presence of coronary risk factors. Determinants of flow response to cold pressor testing (CPT) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885258e6fa0dd3e3dac79dd0d263ea2b
https://doi.org/10.1007/s00259-006-0193-4

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PET-measured heterogeneity in longitudinal myocardial blood flow in response to sympathetic and pharmacologic stress as a non-invasive probe of epicardial vasomotor dysfunction

Autor: James Sayre, Heinrich R. Schelbert, Michael Kreissl, Thomas H. Schindler, Masayuki Inubushi, Alvaro D. Facta, Roxana Campisi, Magnus Dahlbom, Xiaoli Zhang, John O. Prior

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 33:1140-1149

We investigated whether a myocardial perfusion gradient during pharmacologically induced hyperemia also occurred during sympathetic stimulation with cold pressor testing (CPT), which commonly induces a paradoxical coronary vasoconstriction in individ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e154beda9417582fe47e5882e3886f
https://doi.org/10.1007/s00259-006-0069-7

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Coronary Circulatory Dysfunction in Insulin Resistance, Impaired Glucose Tolerance, and Type 2 Diabetes Mellitus

Autor: Willa A. Hsueh, Alvaro D. Facta, Heinrich R. Schelbert, Miguel Hernandez-Pampaloni, James Sayre, Thomas H. Schindler, John O. Prior, Manuel J. Quiñones

Publikováno v: Circulation. 111:2291-2298

Background— Abnormal coronary endothelial reactivity has been demonstrated in diabetes and is associated with an increased rate of cardiovascular events. Our objectives were to investigate the presence of functional coronary circulatory abnormaliti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199056ff2fabaa32f3f4624d181b16be
https://doi.org/10.1161/01.cir.0000164232.62768.51

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Chronic Inflammation and Impaired Coronary Vasoreactivity in Patients With Coronary Risk Factors

Autor: Michael Mix, Egbert U. Nitzsche, Ulrich Solzbach, Nobuhisa Magosaki, Thomas H. Schindler, Heinrich R. Schelbert, Hanjoerg Just, Alvaro D. Facta, Manfred Olschewski, John O. Prior

Publikováno v: Circulation. 110:1069-1075

Background— The goal of this study was to examine a possible association between systemic microinflammation, as reflected by C-reactive protein (CRP) serum levels, and coronary vasomotion in patients with coronary risk factors but with angiographic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77955deae3ddfb19a82fab52e7a8c96a
https://doi.org/10.1161/01.cir.0000140264.56496.76

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Myocardial viability in patients with ischemic cardiomyopathy? evaluation by 3-D integration of myocardial scintigraphic data?and coronary angiographic data

Autor: Thomas H. Schindler, Michael Mix, Heinrich R. Schelbert, Egbert U. Nitzsche, Hanjoerg Just, Nobuhisa Magosaki, Ulrich Solzbach, Alvaro D. Facta, John O. Prior

Publikováno v: Molecular Imaging & Biology. 6:160-171

Purpose To determine the prevalence of viable myocardium in patients with ischemic cardiomyopathy and, to evaluate the value of three-dimensional (3-D) fusion imaging of myocardial scintigraphic and angiographic data to assign coronary artery lesions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a640a7f81ace2553f12642eeec65b0
https://doi.org/10.1016/j.mibio.2004.02.002

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Structural alterations of the coronary arterial wall are associated with myocardial flow heterogeneity in type 2 diabetes mellitus

Autor: Thomas H. Schindler, John O. Prior, Jonathan G. Goldin, Alvaro D. Facta, Xiaoli Zhang, Heinrich R. Schelbert, Jerson Cadenas, James Sayre, Yanjie Li

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 36, No 2 (2009) pp. 219-229

PURPOSE: To determine the relationship between carotid intima-media thickness (IMT), coronary artery calcification (CAC), and myocardial blood flow (MBF) at rest and during vasomotor stress in type 2 diabetes mellitus (DM). METHODS: In 68 individuals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c75e26fd0544bc2af763b3f1e1bff87
https://archive-ouverte.unige.ch/unige:20083

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Relationship between increasing body weight, insulin resistance, inflammation, adipocytokine leptin, and coronary circulatory function

Autor: Heinrich R. Schelbert, Magnus Dahlbom, Thomas H. Schindler, Jerson Cardenas, Julio Licinio, Alvaro D. Facta, Xiaoli Zhang, Michael Kreissl, John O. Prior, James Sayre

Publikováno v: Journal of the American College of Cardiology. 47(6)

ObjectivesWe sought to evaluate effects of obesity, insulin resistance, and inflammation on coronary circulatory function and its relationship to leptin plasma levels.BackgroundIt is not known whether obesity, commonly paralleled by insulin resistanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc11394eeb42aaacae5ebce4cdb91b9e
https://pubmed.ncbi.nlm.nih.gov/16545651

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