Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Alvaro A. Martinez"'
Autor:
Aitor Martinez, Alvaro Sanchez-Martinez, Jake T. Pickering, Madeleine J. Twyning, Ana Terriente-Felix, Po-Lin Chen, Chun-Hong Chen, Alexander J. Whitworth
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract Background Mitochondrial dysfunction and toxic protein aggregates have been shown to be key features in the pathogenesis of neurodegenerative diseases, such as Parkinson’s disease (PD). Functional analysis of genes linked to PD have reveal
Externí odkaz:
https://doaj.org/article/2aa9e015c08a421a94ce4e2d5ab28568
Autor:
Jorge Piano Simoes, Stefan Schoisswohl, Winfried Schlee, Laura Basso, Alberto Bernal-Robledano, Benjamin Boecking, Rilana Cima, Sam Denys, Milena Engelke, Alba Escalera-Balsera, Alvaro Gallego-Martinez, Silvano Gallus, Dimitris Kikidis, Jose A. López-Escámez, Steven C. Marcrum, Nikolaos Markatos, Juan Martin-Lagos, Marta Martinez-Martinez, Birgit Mazurek, Evgenia Vassou, Carlotta Micaela Jarach, Nicolas Mueller-Locatelli, Patrick Neff, Uli Niemann, Hafez Kader Omar, Clara Puga, Miro Schleicher, Vishnu Unnikrishnan, Patricia Perez-Carpena, Rüdiger Pryss, Paula Robles-Bolivar, Matthias Rose, Martin Schecklmann, Tabea Schiele, Johannes Schobel, Myra Spiliopoulou, Sabine Stark, Carsten Vogel, Nina Wunder, Zoi Zachou, Berthold Langguth
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Tinnitus is a leading cause of disease burden globally. Several therapeutic strategies are recommended in guidelines for the reduction of tinnitus distress; however, little is known about the potentially increased effectiveness of
Externí odkaz:
https://doaj.org/article/4c37d8da6c694196b01b2c986bd96268
Autor:
Daniel Casanueva-Morato, Alvaro Ayuso-Martinez, Juan P. Dominguez-Morales, Angel Jimenez-Fernandez, Gabriel Jimenez-Moreno, Fernando Perez-Peña
Publikováno v:
Advanced Intelligent Systems, Vol 5, Iss 11, Pp n/a-n/a (2023)
The brain has great capacity for computation and efficient resolution of complex problems, far surpassing modern computers. Neuromorphic engineering seeks to mimic the basic principles of the brain to develop systems capable of achieving such capabil
Externí odkaz:
https://doaj.org/article/41617e81d07b4c569ee7f93ae3aa0ad9
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/c3d2e9f7b2544f13bbc80bd4abe7be0c
Using coding and non-coding rare variants to target candidate genes in patients with severe tinnitus
Autor:
Alvaro Gallego-Martinez, Alba Escalera-Balsera, Natalia Trpchevska, Paula Robles-Bolivar, Pablo Roman-Naranjo, Lidia Frejo, Patricia Perez-Carpena, Jan Bulla, Silvano Gallus, Barbara Canlon, Christopher R. Cederroth, Jose A. Lopez-Escamez
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Tinnitus is the phantom percept of an internal non-verbal set of noises and tones. It is reported by 15% of the population and it is usually associated with hearing and/or brain disorders. The role of structural variants (SVs) in coding and
Externí odkaz:
https://doaj.org/article/5734f936892f451682d332dfb3663313
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002244 (2023)
Functional analyses of genes linked to heritable forms of Parkinson's disease (PD) have revealed fundamental insights into the biological processes underpinning pathogenic mechanisms. Mutations in PARK15/FBXO7 cause autosomal recessive PD and FBXO7 h
Externí odkaz:
https://doaj.org/article/e900e718fce2414b9f2634cbcbed0576
Autor:
Jaimie C. Hunnam, Kevin Lawrence, Zul Bahar A. Rashid, Ben Hitchcock, Scott McDougall, Alvaro Wehrle-Martinez, Jenny F. Weston
Publikováno v:
Animals, Vol 14, Iss 3, p 524 (2024)
A multi-method approach integrating data from four independent sources was used to describe some key features of the epidemiology and estimate the herd and within-herd incidence of fractured humeri in New Zealand dairy cattle for the period 2007–20
Externí odkaz:
https://doaj.org/article/033bffbda51d493c8799d27964e57f63
Publikováno v:
Investigações em Ensino de Ciências, Vol 28, Iss 1 (2023)
El desarrollo de habilidades tecnológicas y digitales por parte del profesorado en todos los niveles educativos es una necesidad imperante. Con este documento se propone una estrategia de formación para profesores de química mediante el diseño di
Externí odkaz:
https://doaj.org/article/ec63984035c64470a305f6708facfcbf
Autor:
Alvaro Wehrle-Martinez, Mark R. Waterland, Rafea Naffa, Kevin Lawrence, Penny J. Back, Chris W. Rogers, Keren Dittmer
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
The occurrence of spontaneous humeral fractures in primiparous dairy cows from New Zealand prompted the study of bone material from affected cows to further characterize this condition and to outline a likely pathogenesis. Previous studies indicate t
Externí odkaz:
https://doaj.org/article/70e30efa4d2f47299f4c63329d4264bf
Publikováno v:
eLife, Vol 12 (2023)
Respiratory complex I powers ATP synthesis by oxidative phosphorylation, exploiting the energy from NADH oxidation by ubiquinone to drive protons across an energy-transducing membrane. Drosophila melanogaster is a candidate model organism for complex
Externí odkaz:
https://doaj.org/article/ad1c220c53c643f5807e51799c860ca4