Zobrazeno 1 - 10
of 1 047
pro vyhledávání: '"Alvaro, Alonso"'
Zk-SNARKs help scale blockchains with Verifiable Off-chain Computations (VOC). zk-SNARK DSL toolkits are key when designing arithmetic circuits but fall short of automating the subsequent proof-generation step in an automated manner. We emphasize the
Externí odkaz:
http://arxiv.org/abs/2404.16915
Autor:
Wendy Wang, PhD, MPH, Jorge L. Reyes, MD, MS, Abayomi Oyenuga, MD, MPH, Anne A. Eaton, PhD, MS, Faye L. Norby, PhD, MPH, Romil Parikh, MBBS, MPH, Riccardo M. Inciardi, MD, Alvaro Alonso, MD, PhD, Pamela L. Lutsey, PhD, MPH, Charles A. Herzog, MD, Junichi Ishigami, MD, PhD, Kunihiro Matsushita, MD, PhD, Josef Coresh, MD, PhD, Amil M. Shah, MD, Scott D. Solomon, MD, Lin Yee Chen, MD, MS
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 8, Iss 4, Pp 343-355 (2024)
Objective: To examine the association of left atrial (LA) function with incident chronic kidney disease (CKD) and assess the clinical utility of adding LA function to a CKD risk prediction equation. Patients and Methods: We included 4002 Atherosclero
Externí odkaz:
https://doaj.org/article/02a60ecba8534172ae14c25a50ecc7eb
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Cigarette smoking and physical inactivity are two critical risk factors for noncommunicable diseases and all-cause mortality. However, few studies have compared the long-term trajectories of both behaviors, as well as multilevel f
Externí odkaz:
https://doaj.org/article/d9d8822fe26e44909c7e36fa03d97fb7
Autor:
Aniqa B. Alam, Estefania Toledo‐Atucha, Dora Romaguera, Angel M. Alonso‐Gómez, Miguel A. Martínez‐Gonzalez, Lucas Tojal‐Sierra, Marta Noris Mora, Caterina Mas‐Llado, Linzi Li, Ines Gonzalez‐Casanova, Jordi Salas‐Salvadó, Montserrat Fitó, Alvaro Alonso
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 7 (2024)
Background Excessive alcohol consumption has been associated with increased risk of atrial fibrillation, although the underlying mechanisms remain unclear. An enlarged left atrium and impaired left atrial function may lead to atrial fibrillation. The
Externí odkaz:
https://doaj.org/article/907dfde640d64caa931aaeaf8e7282d5
Autor:
Jean Ikanga, Sarah D. Patrick, Megan Schwinne, Saranya Sundaram Patel, Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho, Samuel Mampunza, Kevin E. Yarasheski, Charlotte E. Teunissen, Anthony Stringer, Allan Levey, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Adam L. Boxer, Andreas Jeromin, Alvaro Alonso, Robert J. Spencer
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundThe current study examined the sensitivity of two memory subtests and their corresponding learning slope metrics derived from the African Neuropsychology Battery (ANB) to detect amyloid pathology and APOEε4 status in adults from Kinshasa,
Externí odkaz:
https://doaj.org/article/e3d94e435dd849f58ef490f65ed9a352
Autor:
Takeki Suzuki, Xiaoqian Zhu, Selcuk Adabag, Kunihiro Matsushita, Kenneth R. Butler, Michael E. Griswold, Alvaro Alonso, Wayne Rosamond, Nona Sotoodehnia, Thomas H. Mosley
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 6 (2024)
Background Sudden cardiac death (SCD) is a significant global public health problem accounting for 15% to 20% of all deaths. A great majority of SCD is associated with coronary heart disease, which may first be detected at autopsy. The ankle–brachi
Externí odkaz:
https://doaj.org/article/361197e9478e4ea4bcd87dad4f06851e
Autor:
Alvaro Alonso, Alanna A. Morris, Ashley I. Naimi, Aniqa B. Alam, Linzi Li, Vinita Subramanya, Lin Yee Chen, Pamela L. Lutsey
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 6 (2024)
Background Contemporary use of sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) and angiotensin receptor‐neprilysin inhibitors (ARNi) in patients with atrial fibrillation (AF) and heart failure (HF) has not been described. Methods and Results
Externí odkaz:
https://doaj.org/article/7adaedc839c14ea2a7c3fbe2e2a911d0
Autor:
Yun Soo Hong, Stephanie L. Battle, Wen Shi, Daniela Puiu, Vamsee Pillalamarri, Jiaqi Xie, Nathan Pankratz, Nicole J. Lake, Monkol Lek, Jerome I. Rotter, Stephen S. Rich, Charles Kooperberg, Alex P. Reiner, Paul L. Auer, Nancy Heard-Costa, Chunyu Liu, Meng Lai, Joanne M. Murabito, Daniel Levy, Megan L. Grove, Alvaro Alonso, Richard Gibbs, Shannon Dugan-Perez, Lukasz P. Gondek, Eliseo Guallar, Dan E. Arking
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mitochondria carry their own circular genome and disruption of the mitochondrial genome is associated with various aging-related diseases. Unlike the nuclear genome, mitochondrial DNA (mtDNA) can be present at 1000 s to 10,000 s copies in so
Externí odkaz:
https://doaj.org/article/8424ec81fd124e7695c09c8c5db1a8bc
Autor:
Linzi Li, Alvaro Alonso, Dora Romaguera, Angel M. Alonso-Gómez, Cristina Razquin, Lucas Tojal-Sierra, Miquel Fiol, Miguel Angel Martínez-González, Vinita Subramanya, Jordi Salas-Salvadó, Montserrat Fito, Estefanía Toledo
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 7, p 2132 (2024)
Background: Lifestyles influence atrial fibrillation (AF) risk. Determining the effect of lifestyle interventions on blood concentrations of biomarkers of AF-related pathways could help understand AF pathophysiology and contribute to AF prevention. M
Externí odkaz:
https://doaj.org/article/698420960147440cb19e69194b21fcf5
Autor:
William J. Young, Jeffrey Haessler, Jan-Walter Benjamins, Linda Repetto, Jie Yao, Aaron Isaacs, Andrew R. Harper, Julia Ramirez, Sophie Garnier, Stefan van Duijvenboden, Antoine R. Baldassari, Maria Pina Concas, ThuyVy Duong, Luisa Foco, Jonas L. Isaksen, Hao Mei, Raymond Noordam, Casia Nursyifa, Anne Richmond, Meddly L. Santolalla, Colleen M. Sitlani, Negin Soroush, Sébastien Thériault, Stella Trompet, Stefanie Aeschbacher, Fariba Ahmadizar, Alvaro Alonso, Jennifer A. Brody, Archie Campbell, Adolfo Correa, Dawood Darbar, Antonio De Luca, Jean-François Deleuze, Christina Ellervik, Christian Fuchsberger, Anuj Goel, Christopher Grace, Xiuqing Guo, Torben Hansen, Susan R. Heckbert, Rebecca D. Jackson, Jan A. Kors, Maria Fernanda Lima-Costa, Allan Linneberg, Peter W. Macfarlane, Alanna C. Morrison, Pau Navarro, David J. Porteous, Peter P. Pramstaller, Alexander P. Reiner, Lorenz Risch, Ulrich Schotten, Xia Shen, Gianfranco Sinagra, Elsayed Z. Soliman, Monika Stoll, Eduardo Tarazona-Santos, Andrew Tinker, Katerina Trajanoska, Eric Villard, Helen R. Warren, Eric A. Whitsel, Kerri L. Wiggins, Dan E. Arking, Christy L. Avery, David Conen, Giorgia Girotto, Niels Grarup, Caroline Hayward, J.Wouter Jukema, Dennis O. Mook-Kanamori, Morten Salling Olesen, Sandosh Padmanabhan, Bruce M. Psaty, Cristian Pattaro, Antonio Luiz P. Ribeiro, Jerome I. Rotter, Bruno H. Stricker, Pim van der Harst, Cornelia M. van Duijn, Niek Verweij, James G. Wilson, Michele Orini, Philippe Charron, Hugh Watkins, Charles Kooperberg, Henry J. Lin, James F. Wilson, Jørgen K. Kanters, Nona Sotoodehnia, Borbala Mifsud, Pier D. Lambiase, Larisa G. Tereshchenko, Patricia B. Munroe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The spatial and frontal QRS-T angles are electrocardiographic (ECG) predictors for arrhythmia. This work used genetic analyses to identify associated loci and pathways, and explore their relationships with other ECG traits and cardiovascular disease.
Externí odkaz:
https://doaj.org/article/dafca92a55c441c48a99162ccb2f3205